Abstract
Enzyme loci located on chromosome J and U were mapped cytologically by means of a Y translocation technique. A linkage map of the two chromosomes was established in a parallel experiment and the recombination frequency in different regions of the chromosomes determined. A comparison of the cytogenetic localization of the enzyme genes in D. subobscura and D. melanogaster indicates that many paracentric inversions must have taken place in the course of divergent evolution. However, no displacements of genes from one element to another due to pericentric inversions, reciprocal translocations or transposing elements can be observed. In spite of the large number of structural rearrangements that have occurred in the phylogeny of the genus Drosophila, gross similarities of banding pattern in homologous regions of the chromosomes of the two species become apparent.
Full Text
The Full Text of this article is available as a PDF (1.9 MB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Loukas M., Krimbas C. B. The genetics of Drosophila subobscura populations. V. A study of linkage disequilibrium in natural populations between genes and inversions of the E chromosome. Genetics. 1975 Jun;80(2):331–347. doi: 10.1093/genetics/80.2.331. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Prakash S., Lewontin R. C. A molecular approach to the study of genic heterozygosity in natural populations. 3. Direct evidence of coadaptation in gene arrangements of Drosophila. Proc Natl Acad Sci U S A. 1968 Feb;59(2):398–405. doi: 10.1073/pnas.59.2.398. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Saura A., Lakovaara S., Lokki J., Lankinen P. Genic variation in central and marginal populations of Drosophila subobscura. Hereditas. 1973;75(1):33–45. doi: 10.1111/j.1601-5223.1973.tb01140.x. [DOI] [PubMed] [Google Scholar]
- Sperlich D., Pinsker W. A Y-translocation method for localizing enzyme genes on Drosophila polytene chromosomes. Experientia. 1984 Feb 15;40(2):203–206. doi: 10.1007/BF01963601. [DOI] [PubMed] [Google Scholar]