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. 1984 Dec;108(4):941–952. doi: 10.1093/genetics/108.4.941

Components of Selection in X Chromosome Lines of DROSOPHILA MELANOGASTER: Sex Ratio Modification by Meiotic Drive and Viability Selection

James W Curtsinger 1
PMCID: PMC1224275  PMID: 6439600

Abstract

Selection coefficients and segregation parameters have been estimated in 18 randomly chosen lines carrying wild X chromosomes on the cn bw genetic background. Each line was studied in replicated crosses of four types, with approximately 100 replications per line per cross. Crosses in which male X chromosomes differed exhibited significant sex ratio heterogeneity. Maximum likelihood estimation of segregation parameters revealed two lines in which the proportion of X-bearing gametes produced by males was significantly different from Mendelian expectations. These observations suggest that segregation distortion is a common feature of naturally occurring genetic variation. Non-Mendelian segregation has important evolutionary implications.

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Selected References

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