Abstract
A general procedure is described for measuring and testing population differences in gametic frequencies. The total dispersion among populations is subdivided in hierarchical fashion. The multiple-locus treatment is simply the sum of the single-locus analyses, provided gametic equilibrium obtains among the loci. In the event that gametic equilibrium does not obtain, correlations among loci need to be dealt with.—The analysis is then used to examine the genetic infrastructure of two Indian tribes from South America, the Ye'cuana (Makiritare) and the Yanomama. From historical evidence, we may identify several "clusters" of villages within each tribe. The demographic and cultural practices affecting village formation and the maintenance of peer integrity are rather different in these tribes, however, and lead us to postulate rather different patterns of genetic variation among villages. Analyses of five codominant two-allele loci, four dominant two-allele loci and two complex loci (with four codominant haplotypes each) demonstrate that Yanomama clusters are more disparate than Ye'cuana clusters, as would have been predicted on sociocultural grounds.
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Selected References
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- Chagnon N. A., Neel J. V., Weitkamp L., Gershowitz H., Ayres M. The influence of cultural factors on the demography and pattern of gene flow from the Makiritare to the Yanomama Indians. Am J Phys Anthropol. 1970 May;32(3):339–349. doi: 10.1002/ajpa.1330320304. [DOI] [PubMed] [Google Scholar]
- Hill W. G. Estimation of linkage disequilibrium in randomly mating populations. Heredity (Edinb) 1974 Oct;33(2):229–239. doi: 10.1038/hdy.1974.89. [DOI] [PubMed] [Google Scholar]
- Kojima K., Smouse P., Yang S., Nair P. S., Brncic D. Isozyme frequency patterns in Drosophila pavani associated with geographical and seasonal variables. Genetics. 1972 Dec;72(4):721–731. doi: 10.1093/genetics/72.4.721. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Latter B. D. The estimation of genetic divergence between populations based on gene frequency data. Am J Hum Genet. 1973 May;25(3):247–261. [PMC free article] [PubMed] [Google Scholar]
- Sinnock P., Sing C. F. Analysis of multilocus genetic systems in Tecumseh, Michigan. II. Consideration of the correlation between nonalleles in gametes. Am J Hum Genet. 1972 Jul;24(4):393–415. [PMC free article] [PubMed] [Google Scholar]
- Smouse P. E., Kojima K. Maximum likelihood analysis of population differences in allelic frequencies. Genetics. 1972 Dec;72(4):709–719. doi: 10.1093/genetics/72.4.709. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Spielman R. S., Migliazza E. C., Neel J. V. Regional linguistic and genetic differences among Yanomama indians. Science. 1974 May 10;184(4137):637–644. doi: 10.1126/science.184.4137.637. [DOI] [PubMed] [Google Scholar]
- Tanis R., Ferrell R. E., Nell J. V., Morrow M. Albumin Yanomama-2, a 'private' polymorphism of serum albumin. Ann Hum Genet. 1974 Oct;38(2):179–190. doi: 10.1111/j.1469-1809.1974.tb01949.x. [DOI] [PubMed] [Google Scholar]
- Ward R. H., Gershowitz H., Layrisse M., Neel J. V. The genetic structure of a tribal population, the Yanomama Indians XI. Gene frequencies for 10 blood groups and the ABH-Le secretor traits in the Yanomama and their neighbors; the uniqueness of the tribe. Am J Hum Genet. 1975 Jan;27(1):1–30. [PMC free article] [PubMed] [Google Scholar]
- Ward R. H. The genetic structure of a tribal population, the Yanomama Indians. V. Comparisons of a series of genetic networks. Ann Hum Genet. 1972 Jul;36(1):21–43. doi: 10.1111/j.1469-1809.1972.tb00579.x. [DOI] [PubMed] [Google Scholar]