Abstract
Nodules developing under the skin of rats after repeated injections of N-Nitroso-bis-(2-hydroxy-propyl)amine (BHP) are shown to contain no unchanged BHP
Key words: Skin nodules, Rats, N-Nitroso-bis-(2-hydroxy-propyl)amine (BHP) analysis
References
- 1.Krüger FW, Pour P, Althoff J (1979) Induction of pancreas tumors by diisopropanolnitrosamine. Naturwissenschaften 61:328–329 [DOI] [PubMed] [Google Scholar]
- 2.Rao MS, Reddy JK (1977) Induction of malignant vascular tumors of the liver in guinea pigs treated with 2,2′-dihydroxy-di-n-propylnitrosamin. J Natl Cancer Inst 58:387–392 [DOI] [PubMed] [Google Scholar]
- 3.Mohr U, Reznik G, Pour P (1977) Carcinogenic effects of diisopropanolnitrosamine in Sprague-Dawley rats. J Natl Cancer Inst 58:361–366 [DOI] [PubMed] [Google Scholar]
- 4.Schäffer R, Müller HA, Heine WD (1979) Experimentell erzeugte prämaligne Neoplasien der Rattenschilddrüse. Verh Dtsch Ges Pathol 63:458–461 [Google Scholar]
- 5.Green U, Konishi Y, Ketkar MB, Althoff J (1980) Comparative study of the carcinogenic effect of BHP and BAP on NMRI mice. Cancer Lett 9:257–261 [DOI] [PubMed] [Google Scholar]
- 6.Parsa J, Marsh WH, Sutton AL (1980) An in vitro model of pancreas carcinoma: N-nitroso-bis-(2-hydroxypropyl)amine effects. Cancer Lett 9:1–6 [DOI] [PubMed] [Google Scholar]
- 7.Gingell R, Walcave L, Nagel D, Kupper R, Pour P (1976) Metabolism of the pancreatic carcinogen N-nitroso-bis(2-oxopropyl)amine and N-nitroso-bis(2-hydroxypropyl)amine in the Syrian hamster. J Natl Cancer Inst 57:1175–1178 [DOI] [PubMed] [Google Scholar]
