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Journal of Cancer Research and Clinical Oncology logoLink to Journal of Cancer Research and Clinical Oncology
. 1980 Jan;96(1):27–33. doi: 10.1007/BF00412894

An epithelial cell line (KNS-62) derived from a brain metastasis of bronchial squamous cell carcinoma

T Takaki 1
PMCID: PMC12253417  PMID: 7358770

Abstract

A brain metastasis of bronchial squamous cell carcinoma in a patient was cultivated. The cells with epithelium-like characteristics were selected from the primary culture, and were subcultured to establish a cell line. The cultured cells were identified to be neoplastic by means of heterologous transplantation to nude mice, in which tumors developed and reproduced histologic characteristics as were seen in the primary tumor of the patient.

Key words: Bronchial carcinoma, Epipthelial cell line, Nude mice

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