Editorial Expression of Concern: Rapid onset of cardiomyopathy in STZ-induced female diabetic mice involves the downregulation of pro-survival Pim-1

Editorial Expression of Concern: Cardiovascular Diabetology (2014) 13:68 http://www.cardiab.com/content/13/1/68

The Editor-in-Chief is issuing this expression of concern to alert readers that overlaps have been noted in the following images:

• Fig. 3A—4 weeks Female D Pim-1 and 32 weeks male D Pim-1

• Fig. 3A—12 weeks Male ND and Female ND Pim-1

• Fig. 3B—32 weeks Male and Female—Cleaved Caspase 3

• Figure S4—12 weeks Female ND and 32 weeks Male ND—RIP Kinase

• Figure S4—12 weeks Female D and 32 weeks Female ND—RIP Kinase

Overlap has also been noted between images in Fig. 3E of this article with images in Fig. 3C in a previously published article [1]

• Fig. 3E 4 weeks Bcl 2 Male ND & D and Female ND with Fig. 3C Pbad

• Fig. 3E 4 weeks Bcl 2 female D with Fig. 3C Actin

• Fig. 3E 8 weeks Male ND & D and Female ND with Fig. 3C Bcl-2

Due to the age of the article the authors are no longer able to access the original data for validation.

Ingrid Fomison-Nurse, Federica Riu, Pujika E Munasinghe, Sean Coffey, Richard W Bunton, Michael JA Williams, Costanza Emanueli, Paolo Madeddu and Rajesh Katare agree to this editorial expression of concern. The publisher was unable to find current addresses for Andrew Moore, Amol Shindikar, Thrishila Parshu Ram, Pankaj Saxena and Ivor F Galvin.