Table 2.
Association between the CTI and CVD incidence
| Died/participants | Model 1 | Model 2 | Model 3 | |
|---|---|---|---|---|
| CVD mortality | 1152/8679 | |||
| Q1 | 205/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 313/2170 | 0.99 (0.71–1.39) | 1.01 (0.74–1.40) | 1.45 (1.16–2.23)** |
| Q3 | 335/2170 | 1.22 (0.87–1.71) | 1.24 (0.91–1.69) | 1.92 (1.52–2.81)** |
| Q4 | 299/2169 | 1.43 (0.98–2.08) | 1.63 (1.18–2.24)** | 2.28 (1.69–3.24)** |
| All-cause mortality | 360/8679 | |||
| Q1 | 63/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 91/2170 | 1.10 (0.92–1.32) | 1.08 (0.91–1.29) | 1.62 (1.34–1.92)** |
| Q3 | 108/2170 | 1.23 (1.02–1.48)* | 1.19 (0.99–1.42) | 1.87 (1.49–2.23)** |
| Q4 | 98/2169 | 1.44 (1.17–1.78)** | 1.50 (1.26–1.80)** | 2.14 (1.76–2.55)** |
| Total-CVD | 972/8679 | |||
| Q1 | 140/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 230/2170 | 1.01 (0.79–1.30) | 1.18 (0.94–1.49) | 1.81 (1.42–2.21)** |
| Q2 | 247/2170 | 0.88 (0.68–1.13) | 1.18 (0.94–1.49) | 1.91 (1.49–2.39)** |
| Q4 | 355/2169 | 1.12 (0.86–1.46) | 2.00 (1.61–2.49)** | 2.85 (2.32–3.52)** |
| Congestive heart failure | 283/8679 | |||
| Q1 | 35/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 64/2170 | 1.07 (0.69–1.66) | 1.29 (0.84–1.96) | 1.87 (1.20–2.79)** |
| Q3 | 62/2170 | 0.85 (0.54–1.35) | 1.14 (0.74–1.75) | 1.77 (1.16–2.69)** |
| Q4 | 122/2169 | 1.41 (0.90–2.21) | 2.51 (1.70–3.70)** | 3.66 (2.46–5.35)** |
| Coronary heart disease | 363/8679 | |||
| Q1 | 45/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 99/2170 | 1.49 (1.02–2.20)* | 1.56 (1.08–2.26)* | 2.28 (1.61–3.25)** |
| Q3 | 98/2170 | 1.21 (0.81–1.80) | 1.41 (0.97–2.04) | 2.24 (1.59–3.21)** |
| Q4 | 121/2169 | 1.28 (0.84–1.94) | 1.94 (1.35–2.78)** | 2.82 (1.95–3.97)** |
| Angina pectoris | 235/8679 | |||
| Q1 | 32/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 50/2170 | 0.94 (0.58–1.49) | 1.11 (0.71–1.75) | 1.61 (1.03–2.50)* |
| Q3 | 65/2170 | 0.97 (0.61–1.55) | 1.36 (0.88–2.11) | 2.08 (1.37–3.19)** |
| Q4 | 88/2169 | 1.02 (0.63–1.65) | 1.97 (1.30–2.98)** | 2.85 (1.89–4.22)** |
| Heart attack | 399/8679 | |||
| Q1 | 56/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 101/2170 | 1.16 (0.81–1.65)** | 1.29 (0.92–1.82) | 1.87 (1.32–2.55)** |
| Q3 | 103/2170 | 0.99 (0.68–1.42) | 1.22 (0.87–1.72) | 1.91 (1.36–2.61)** |
| Q4 | 139/2169 | 1.15 (0.79–1.68) | 1.81 (1.31–2.50)** | 2.59 (1.89–3.52)** |
| Stroke | 325/8679 | |||
| Q1 | 46/2170 | 1 (referent) | 1 (referent) | 1 (referent) |
| Q2 | 76/2170 | 0.98 (0.66–1.45) | 1.17 (0.80–1.71) | 1.54 (1.04–2.22)** |
| Q3 | 78/2170 | 0.83 (0.55–1.25) | 1.11 (0.76–1.62) | 1.50 (1.08–2.27)** |
| Q4 | 125/2169 | 1.18 (0.78–1.77) | 1.94 (1.37–2.75)** | 2.86 (2.00–3.85)** |
Model 1 did not adjust for any variables. Model 2 adjusted for sex and age. Model 3 adjusted for age, sex, education, race, smoking, alcohol use, self-reported diabetes, self-reported hypertension, systolic blood pressure (SBP), BMI, HDL, LDL, and HbA1c% levels
*P < 0.05, **P < 0.01