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. 1986 Feb;55(2):162–167. doi: 10.1136/hrt.55.2.162

Computer assisted echocardiographic assessment of left ventricular function before and after anatomical correction of transposition of the great arteries.

F W Arensman, R Radley-Smith, L Grieve, D G Gibson, M H Yacoub
PMCID: PMC1232112  PMID: 3942650

Abstract

Left ventricular function before and after anatomical correction of transposition of the great arteries was assessed by computer assisted analysis of 78 echocardiographs from 27 patients obtained one year before to five years after operation. Sixteen patients had simple transposition, and 11 had complex transposition with additional large ventricular septal defect. Immediately after correction mean shortening fraction fell from 46(9)% to 33(8)%. There was a corresponding drop in normalised peak shortening rate from 5.4(3.7) to 3.3(1.1) s-1 and normal septal motion was usually absent. Systolic shortening fraction increased with time after correction and left ventricular end diastolic diameter increased appropriately for age. The preoperative rate of free wall thickening was significantly higher in simple (5.6(2.8) s-1) and complex transposition (4.5(1.8) s-1) than in controls (2.9(0.8) s-1). After operation these values remained high in both the short and long term. Thus, computer assisted analysis of left ventricular dimensions and their rates of change before and after anatomical correction showed only slight postoperative changes which tended to become normal with time. Septal motion was commonly absent after operation. This was associated with an increase in the rate of posterior wall thickening that suggested normal ventricular function associated with an altered contraction pattern. Computer assisted echocardiographic analysis may be helpful in the long term assessment of ventricular function after operation for various heart abnormalities.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Arensman F. W., Radley-Smith R., Yacoub M. H., Lange P., Bernhard A., Sievers H. H., Heintzen P. Catheter evaluation of left ventricular shape and function 1 or more years after anatomic correction of transposition of the great arteries. Am J Cardiol. 1983 Nov 1;52(8):1079–1083. doi: 10.1016/0002-9149(83)90536-2. [DOI] [PubMed] [Google Scholar]
  2. Biancaniello T., Meyer R. A., Wong K. Y., Sager C., Kaplan S. Doxorubicin cardiotoxicity in children. J Pediatr. 1980 Jul;97(1):45–50. doi: 10.1016/s0022-3476(80)80128-4. [DOI] [PubMed] [Google Scholar]
  3. Borow K. M., Arensman F. W., Webb C., Radley-Smith R., Yacoub M. H. Assessment of left ventricular contractile state after anatomic correction of transposition of the great arteries. Circulation. 1984 Jan;69(1):106–112. doi: 10.1161/01.cir.69.1.106. [DOI] [PubMed] [Google Scholar]
  4. Burggraf G. W., Craige E. Echocardiographic studies of left ventricular wall motion and dimensions after valvular heart surgery. Am J Cardiol. 1975 Apr;35(4):473–480. doi: 10.1016/0002-9149(75)90829-2. [DOI] [PubMed] [Google Scholar]
  5. Cordell D., Graham T. P., Jr, Atwood G. F., Boerth R. C., Boucek R. J., Bender H. W. Left heart volume characteristics following ventricular septal defect closure in infancy. Circulation. 1976 Aug;54(2):294–298. doi: 10.1161/01.cir.54.2.294. [DOI] [PubMed] [Google Scholar]
  6. Duncan W. J., Freedom R. M., Rowe R. D., Olley P. M., Williams W. G., Trusler G. A. Echocardiographic features before and after the Jatene procedure (anatomical correction) for transposition of the great vessels. Am Heart J. 1981 Aug;102(2):227–232. doi: 10.1016/s0002-8703(81)80014-2. [DOI] [PubMed] [Google Scholar]
  7. Gibson D. G., Brown D. Measurement of instantaneous left ventricular dimension and filling rate in man, using echocardiography. Br Heart J. 1973 Nov;35(11):1141–1149. doi: 10.1136/hrt.35.11.1141. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Gibson D. G., Traill T. A., Brown D. J. Changes in left ventricular free wall thickness in patients with ischaemic heart disease. Br Heart J. 1977 Dec;39(12):1312–1318. doi: 10.1136/hrt.39.12.1312. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Graham T. P., Jr Hemodynamic residua and sequelae following intraatrial repair of transposition of the great arteries: a review. Pediatr Cardiol. 1982;2(3):203–213. doi: 10.1007/BF02332111. [DOI] [PubMed] [Google Scholar]
  10. Hagler D. J., Ritter D. G., Mair D. D., Tajik A. J., Seward J. B., Fulton R. E., Ritman E. L. Right and left ventricular function after the Mustard procedure in transposition of the great arteries. Am J Cardiol. 1979 Aug;44(2):276–283. doi: 10.1016/0002-9149(79)90317-5. [DOI] [PubMed] [Google Scholar]
  11. Jarmakani J. M., Graham T. P., Jr, Canent R. V., Jr, Capp M. P. The effect of corrective surgery on left heart volume and mass in children with ventricular septal defect. Am J Cardiol. 1971 Mar;27(3):254–258. doi: 10.1016/0002-9149(71)90299-2. [DOI] [PubMed] [Google Scholar]
  12. MUSTARD W. T. SUCCESSFUL TWO-STAGE CORRECTION OF TRANSPOSITION OF THE GREAT VESSELS. Surgery. 1964 Mar;55:469–472. [PubMed] [Google Scholar]
  13. Nixon J. V., Atkins J. M., Curry G. C., Buja L. M., Miller W. W. Late right ventricular failure after Mustard operation for transposition of the great arteries. Cathet Cardiovasc Diagn. 1978;4(2):175–182. [PubMed] [Google Scholar]
  14. Ross R. S. The next 30 years--will the progress continue? Circulation. 1980 Jul;62(1):1–7. doi: 10.1161/01.cir.62.1.1. [DOI] [PubMed] [Google Scholar]
  15. SENNING A. Surgical correction of transposition of the great vessels. Surgery. 1959 Jun;45(6):966–980. [PubMed] [Google Scholar]
  16. Sahn D. J., DeMaria A., Kisslo J., Weyman A. Recommendations regarding quantitation in M-mode echocardiography: results of a survey of echocardiographic measurements. Circulation. 1978 Dec;58(6):1072–1083. doi: 10.1161/01.cir.58.6.1072. [DOI] [PubMed] [Google Scholar]
  17. Silverman N. H., Payot M., Stanger P., Rudolph A. M. The echocardiographic profile of patients after Mustard's operation. Circulation. 1978 Dec;58(6):1083–1093. doi: 10.1161/01.cir.58.6.1083. [DOI] [PubMed] [Google Scholar]
  18. St John Sutton M. G., Marier D. L., Oldershaw P. J., Sacchetti R., Gibson D. G. Effect of age related changes in chamber size, wall thickness, and heart rate on left ventricular function in normal children. Br Heart J. 1982 Oct;48(4):342–351. doi: 10.1136/hrt.48.4.342. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Yacoub M. H., Radley-Smith R., Hilton C. J. Anatomical correction of complete transposition of the great arteries and ventricular septal defect in infancy. Br Med J. 1976 May 8;1(6018):1112–1114. doi: 10.1136/bmj.1.6018.1112. [DOI] [PMC free article] [PubMed] [Google Scholar]
  20. Yacoub M. H. The case for anatomic correction of transposition of the great arteries. J Thorac Cardiovasc Surg. 1979 Jul;78(1):3–6. [PubMed] [Google Scholar]

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