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Molecular Neurodegeneration logoLink to Molecular Neurodegeneration
. 2025 Aug 5;20:87. doi: 10.1186/s13024-025-00881-6

Retraction Note: Hippocampal neuronal cells that accumulate α-synuclein fragments are more vulnerable to Aβ oligomer toxicity via mGluR5– implications for dementia with lewy bodies

Cassia R Overk 1, Anna Cartier 1, Gideon Shaked 1, Edward Rockenstein 1, Kiren Ubhi 1, Brian Spencer 1, Diana L Price 2, Christina Patrick 1, Paula Desplats 1, Eliezer Masliah 1,3,
PMCID: PMC12323172  PMID: 40759974

Retraction Note

The Editorial team has retracted this article.

After publication, concerns were raised regarding some of the data presented in the figures. Specifically:

  • Panels Non tg and APP tg in the second row of Fig. 5A appear to overlap;

  • Panels Non tg in the third rows of Fig. 6B and D appear to overlap;

  • Panels APP tg and alpha-syn tg in the first row of Fig. 7D appear to overlap;

  • Panels Non-tg in the second rows of Fig. 7B and D appear to overlap;

  • Panels APP tg and alpha-syn tg in the third row of Fig. 7D appear to overlap;

  • Some blots in Fig. 9c appear to have similar bands between the two LV-control groups (vehicle and Aβ1–42).

The authors have stated that these errors occurred during figure preparation. However, due to the number of concerns, the Editors-in-Chief no longer have confidence in the presented data.

Cassia R Overk and Eliezer Masliah disagree with this retraction. The other authors have not responded to any correspondence from the editor or publisher about this retraction.

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