Skip to main content
Journal of Anatomy logoLink to Journal of Anatomy
. 1980 Oct;131(Pt 3):565–575.

The human vertebral column at the end of the embryonic period proper. 1. The column as a whole.

R O'Rahilly, F Muller, D B Meyer
PMCID: PMC1233253  PMID: 7216919

Abstract

The present investigation of the vertebral column at 8 post-ovulatory weeks, the first such study based on precise reconstructions, has revealed 33 or 34 cartilaginous vertebrae arranged in flexion and approximately 20--33 mm in total length. At the end of the embryonic period proper, a typical vertebra, such as TV6, consists of a centrum that is continuous with two neural processes. Pedicles, articular and transverse processes, but no spinous processes, are identifiable. The tips of the neural processes, which are formed by the laminae, are connected by fibrous tissue and resemble the condition of total rachischisis. The union of the laminae, the onset of ossification, and the appearance of articular cavities are characteristic of the early fetal period. The variations encountered within a single developmental stage were noted. They were mostly minor, e.g. the number of coccygeal elements and the extent of the dorsal growth of the neural processes.

Full text

PDF
565

Images in this article

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. BARRY A. A quantitative study of the prenatal changes in angulation of the spinal nerves. Anat Rec. 1956 Sep;126(1):97–110. doi: 10.1002/ar.1091260108. [DOI] [PubMed] [Google Scholar]
  2. Bagnall K. M., Harris P. F., Jones P. R. A radiographic study of the human fetal spine. 1. The development of the secondary cervical curvature. J Anat. 1977 Jul;123(Pt 3):777–782. [PMC free article] [PubMed] [Google Scholar]
  3. Bagnall K. M., Harris P. F., Jones P. R. A radiographic study of the human fetal spine. 2. The sequence of development of ossification centres in the vertebral column. J Anat. 1977 Dec;124(Pt 3):791–802. [PMC free article] [PubMed] [Google Scholar]
  4. Bagnall K. M., Harris P. F., Jones P. R. A radiographic study of the human fetal spine. 3. Longitudinal growth. J Anat. 1979 Jun;128(Pt 4):777–787. [PMC free article] [PubMed] [Google Scholar]
  5. Barson A. J. Spina bifida: the significance of the level and extent of the defect to the morphogenesis. Dev Med Child Neurol. 1970 Apr;12(2):129–144. doi: 10.1111/j.1469-8749.1970.tb01881.x. [DOI] [PubMed] [Google Scholar]
  6. Barson A. J. The vertebral level of termination of the spinal cord during normal and abnormal development. J Anat. 1970 May;106(Pt 3):489–497. [PMC free article] [PubMed] [Google Scholar]
  7. Friedland G. W., de Vries P. Renal ectopia and fusion. Embryologic Basis. Urology. 1975 May;5(5):698–706. doi: 10.1016/0090-4295(75)90137-5. [DOI] [PubMed] [Google Scholar]
  8. MEYER D. B., O'RAHILLY R. Roentgenographic investigation of the human skeleton during early fetal life. Am J Roentgenol Radium Ther Nucl Med. 1956 Sep;76(3):455–468. [PubMed] [Google Scholar]
  9. NOBACK C. R., ROBERTSON G. G. Sequences of appearance of ossification centers in the human skeleton during the first five prenatal months. Am J Anat. 1951 Jul;89(1):1–28. doi: 10.1002/aja.1000890102. [DOI] [PubMed] [Google Scholar]
  10. O'Rahilly R. Early human development and the chief sources of information on staged human embryos. Eur J Obstet Gynecol Reprod Biol. 1979 Aug;9(4):273–280. doi: 10.1016/0028-2243(79)90068-6. [DOI] [PubMed] [Google Scholar]
  11. O'Rahilly R., Meyer D. B. The timing and sequence of events in the development of the human vertebral column during the embryonic period proper. Anat Embryol (Berl) 1979 Oct;157(2):167–176. doi: 10.1007/BF00305157. [DOI] [PubMed] [Google Scholar]
  12. PEACOCK A. Observations on the prenatal development of the intervertebral disc in man. J Anat. 1951 Jul;85(3):260–274. [PMC free article] [PubMed] [Google Scholar]
  13. Taylor J. R. Persistence of the notochordal canal in vertebrae. J Anat. 1972 Feb;111(Pt 2):211–217. [PMC free article] [PubMed] [Google Scholar]
  14. WALMSLEY R. The development and growth of the intervertebral disc. Edinb Med J. 1953 Aug;60(8):341–364. [PMC free article] [PubMed] [Google Scholar]
  15. Wyburn G. M. Observations on the development of the human vertebral column. J Anat. 1944 Apr;78(Pt 3):94–102.2. [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Anatomy are provided here courtesy of Anatomical Society of Great Britain and Ireland

RESOURCES