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. 1996 Sep;71(3):1335–1345. doi: 10.1016/S0006-3495(96)79333-5

A biophysical model for defibrillation of cardiac tissue.

J P Keener 1, A V Panfilov 1
PMCID: PMC1233600  PMID: 8874007

Abstract

We propose a new model for electrical activity of cardiac tissue that incorporates the effects of cellular microstructure. As such, this model provides insight into the mechanism of direct stimulation and defibrillation of cardiac tissue after injection of large currents. To illustrate the usefulness of the model, numerical stimulations are used to show the difference between successful and unsuccessful defibrillation of large pieces of tissue.

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Selected References

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