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PLOS One logoLink to PLOS One
. 2025 Aug 12;20(8):e0329375. doi: 10.1371/journal.pone.0329375

Does low fertility indicate better reproductive health status? Evidence from nationally representative survey in India

Roni Sikdar 1,*, Dhananjay W Bansod 1
Editor: Pijush Kanti Khan2
PMCID: PMC12342277  PMID: 40794749

Abstract

Background

The global demographic landscape is experiencing a significant transformation of declining fertility rates, which has far-reaching implications for societal development and women’s well-being. The study investigates the association between declining fertility rates and women’s reproductive health in India, considering socioeconomic and demographic factors as well as regional variations.

Methods

The study uses data from the recent National Family Health Survey (NFHS-5) round conducted during 2019−21. A composite index called the Reproductive Health Index (RHI) is constructed by equally weighing indicators such as antenatal care, anemia, and body mass index. To evaluate the robustness of this index, a sensitivity analysis is performed. Descriptive statistics and Poisson regression models are employed to explore the association between fertility and RHI among currently married women.

Results

The findings show substantial differences in RHI scores across socio-economic, demographic groups, and geographical regions. The lowest RHI score of 4.09 is found in the Eastern region, whereas those in the Northern region exhibit the highest score of 4.42. The analysis further indicates a negative relationship between fertility and reproductive health. Women with four or more children exhibit an RHI score of 1.97 compared to 2.98 among those with one child. The Poisson regression analysis indicates that women with at least four children have lower RHI scores, even after adjusting for socio-economic and demographic factors. Women in wealthier quintiles and those with media exposure report significantly higher RHI score compared to those in the poorest wealth quintiles and no media exposure.

Conclusion

In conclusion, this research highlights the critical need for targeted interventions to address regional and socio-economic inequities in healthcare access and reproductive health services. By exploring the intricate relationship between low fertility and reproductive health, this study contributes to the discourse on gender equality, reproductive rights, and sustainable societal development. The findings provide evidence to guide public health policies and programs designed to promote women’s reproductive health.

Introduction

The Sustainable Development Goals (SDGs) established by the United Nations emphasise the importance of gender equality and the empowerment of all women and girls. It highlights the need for equitable access to resources and services that enhance the overall well-being of all individuals by 2030. Within this framework, SDG-5 focuses on achieving healthy lives and promoting the well-being of all ages, especially women and girls. It highlights the need for universal health coverage and access to sexual and reproductive health care services [1]. Despite extensive research on fertility trends and their economic and demographic implications, the association between fertility transition and women’s reproductive health remains underexplored.

Previous literature predominantly addresses the economic and societal aspects of fertility decline. Studies have shown that lower fertility rates can contribute to economic growth and development by enabling women to participate in the workforce [25]. However, these studies often overlook the nuanced health outcomes and personal experiences. For instance, while lower fertility is associated with improved maternal health and reduced mortality rates [6], how it affects women’s overall well-being is less clear. This study addresses this gap by developing a composite Reproductive Health Index (RHI) to provide a comprehensive assessment of women’s health in relation to fertility patterns.

The global demographic landscape is experiencing a significant transformation characterised by declining fertility rates [79]. Recently, India also experiences low fertility, as the latest National Family Health Survey (NFHS-5) shows that the total fertility rate (TFR) of India has decreased to 2.0 from 3.39 in 1992−93 (NFHS-1) [10,11]. The transition towards low fertility rates makes a sharp divergence from India’s long-standing image of high fertility, restructuring the country’s demographic composition [12]. The decline is indicative of broader socio-economic transformation, including increased access to education, improved healthcare services, and enhanced economic opportunities for women [1320]. However, the implications of these changes on women’s reproductive health are complex and multifaceted. This requires closer examination.

A unique aspect of this study is its focus on geographical variations in the impact of low fertility on women’s well-being across different regions of India. Previous studies largely focus on national averages, failing to capture regional disparities [2124]. By highlighting these differences, this research provides valuable insights for region-specific policy interventions. It helps to understand how different regions within the country experience and respond to fertility changes, which is crucial for developing targeted strategies that address the unique needs of women in diverse contexts.

Several theoretical perspectives inform this study. Yukiko Asada developed a framework to measure health inequity, which aims to understand the complexities of moral and ethical dimensions within broader systemic disparities in access to healthcare, nutrition, and education [25]. Studies indicate that socioeconomic status, regional healthcare infrastructure, and social stratification play a major role in health outcomes [2628]. For women in rural or marginalised communities, the potential benefits of improved reproductive healthcare associated with fertility decline are often overshadowed by barriers such as inadequate access to antenatal care and persistent nutritional deficits [29,30]. The capability approach developed by Sen (1999) provides another approach to understanding how fertility decline intersects with women’s well-being. Fertility reduction is often associated with enhanced access to education, workforce participation, and quality healthcare [3133]. However, existing studies reveal a critical inequity: While fertility is linked with better health outcomes, these benefits are unevenly distributed. Women from lower socio-economic groups are often excluded from these advantages due to systemic barriers, including limited access to quality healthcare and socio-cultural constraints [34,35]. This underscores the importance of framing reproductive health not solely as an outcome but as a capability that requires active nurturing through equitable and inclusive policy interventions [36,37]. The life course perspective further adds different sheds by exploring how early life events and cumulative disadvantages shape reproductive health trajectories. Early marriages, high fertility rates, and inadequate access to healthcare during reproductive stages significantly increases the risks of adverse health outcomes [38,39]. Women who experience these compounded disadvantages are less likely to get the benefit of low fertility, perpetuating reproductive health inequities. This framework highlights the importance of addressing structural disadvantages across all stages of life to ensure that the benefits of low fertility are equitably distributed [40,41].

The World Health Organisation defines reproductive health as a state of complete physical, mental, and social well-being and not merely the absence of disease or infirmity in all matters relating to the reproductive system [42]. This comprehensive definition underscores the necessity of considering a wide range of health indicators when assessing women’s reproductive health. Despite extensive research on the socio-economic consequences of fertility decline, there remains limited evidence on its direct implications for women’s reproductive health. Most of the studies focus on economic benefits, workforce participation, and maternal mortality but do not capture broader health indicators. Furthermore, national studies highlight state-level differences and often lack district-level insights. This study addresses this gap by developing the Reproductive Health Index (RHI). RHI incorporates various indicators to provide a comprehensive assessment of women’s health in relation to fertility.

By integrating these various dimensions, this study aims to offer a more comprehensive understanding of the impact of low fertility on women’s reproductive health. We set out to answer two research questions: (1) What is the extent of RHI in India? (2) How does low fertility impact the reproductive health of women in India, considering socioeconomic and demographic factors as well as regional variations? These findings underscore the need for targeted policies that address systemic inequities, promote reproductive rights, and ensure that the benefits of low fertility translate into substantive improvements in women’s reproductive health.

Methods

Data sources

The study uses data from the NFHS-5 conducted in India in 2019−21. The International Institute for Population Sciences (IIPS) in Mumbai conducted this survey with funding from the Government of India’s Ministry of Health and Family Welfare. The NFHS is a nationally representative household survey that provides comprehensive data for monitoring and evaluating various indicators related to population, health, and nutrition. The survey design is optimized to ensure high precision in fertility and family planning indicators. The survey was approved by the Institutional Review Board (IRB) of the institutions involved. The detailed datasets are available at (https://dhsprogram.com/data/dataset/India_Standard-DHS_2020.cfm?flag=1). This datasets is entirely anonymized and does not contain any personally identifiable information about respondents, households, or communities. Therefore, ethical approval was not required for this study. The NFHS 2019−21 report was developed to offer assessments of essential indicators at the national level (28 states, 8 union territories) and district level (707 districts). Using a two-stage stratified sampling design, the NFHS −5 sample surveyed 636,699 households and 724,115 women of reproductive age with a 97% response rate [11].

In this study, women who report never having been in a union, divorced, or separated and have no children are excluded. Our analytic sample includes an average of 173,966 women aged 15–49 years who are currently married or in a union (hereafter referred to as partnered women) who gave birth to at least one child in the 5-year period preceding the survey.

Study variables and their measurement

We use the women’s module to explore the reproductive health status of women. This module includes questions about medical attention at birth, antenatal coverage, ever-experienced stillbirth, early neonatal mortality, the prevalence of anemia, body mass index (BMI), low birth weight, and delivery by cesarean section. In NFHS, BMI is calculated from measured height and weight, while anemia status is determined from haemoglobin levels, and birth outcomes based on reported maternal health experiences. Skilled or unskilled care during antenatal and delivery is obtained from provider-based questions, while cesarean delivery and history of miscarriage or stillbirth serve as additional reproductive health indicators. We exclude abortion from the miscarriage/stillbirth indicator to maintain focus on involuntary and health-related pregnancy losses. We consider these indicators (Table 1) to measure RHI [2224,43,44]. The inclusion of these factors is essential for comprehensively assessing women’s reproductive health status. We compute an individual-level score by adding 7 indicators from 7 questions in the NFHS-5. Equal weights are assigned to each variable, indicating that each is considered equally crucial for measuring women’s reproductive health. Each indicator is associated with a specific threshold value, beyond which a woman is assigned an RHI score. However, it is essential to recognise that women’s RHI is a complex and unfolding process characterised by a progression rather than a simple binary classification. Therefore, we anticipate that our findings will hold significance. To determine the weights for dichotomous variables, a particular approach is employed wherein women facing any adverse reproductive health outcome incur a penalty of 0, while those experiencing any positive reproductive health outcome receive a reward of 1.

Table 1. Variables, Measurement, and Coding of Reproductive Health Index (RHI).

Variable Definitions Code or units
Medical attention at birth It refers to a birth attended by different health personnel. It is essential to measure the diverse health needs of women accurately. Yes = 1
No = 0
Antenatal coverage Antenatal coverage refers to the percentage of women who receive adequate care during pregnancy. It is important to evaluate women’s access to essential health services, thereby providing a comprehensive measure of their reproductive health and well-being. Yes = 1
No = 0
Ever experienced stillbirth It is essential to maternal health challenges and higfhlights disparities across different groups. Ever experience stillbirth refers to women who have reported experiencing a stillbirth at any point in their life. Yes = 0
No = 1
Prevalence of Anaemia in women Anaemia refers to the proportion of women who have hemoglobin levels below the normal range. It is important to identify nutritional and health deficiencies. Yes = 0
No = 1
BMI Body Mass Index is measured by height and weight to see the nutritional and health status across different groups. Normal weight (18.5–24.9 kg/m2) = 1
Others (<18.5 kg/m2 & ≥ 25.0) = 0
Low birth weight It is defined as infants weighing less than 2.5 kg at birth, and it reflects maternal health and prenatal care quality, reflecting women’s reproductive health. Normal = 1
Below 2.5 kg = 0
Delivered by cesarean section Indicates medical intervention level and maternal healthcare quality, essential for assessing women’s well-being. Yes = 0
No = 1

Source: Adapted from (22–24,44). Note: This variable includes only stillbirth and miscarriage. Abortion is excluded to focus on involuntary pregnancy losses.

The explanatory variable is the number of children ever born (CEB). Further, we include women’s present age, age at first marriage, age at first birth, caste categories, religion, place of residence, and regions like North (Chandigarh, Delhi, Haryana, Himachal Pradesh, Jammu & Kashmir, Ladakh, Punjab, Rajasthan, and Uttarakhand), East (Bihar, Jharkhand, Odisha, and West Bengal), Northeast (Arunachal Pradesh, Assam, Manipur, Meghalaya, Mizoram, Nagaland, Sikkim, and Tripura), Central (Chhattisgarh, Madhya Pradesh, and Uttar Pradesh), West (Dadra & Nagar Haveli and Daman & Diu, Goa, Gujarat, and Maharashtra), and South (Andaman & Nicobar Islands, Andhra Pradesh, Karnataka, Kerala, Lakshadweep, Puducherry, Tamil Nadu, and Telangana) to effectively understand the unadjusted and adjusted association between low fertility and women’s reproductive health.

Statistical analysis

In the beginning, we illustrate the percentage distribution of each variable within the framework of this country. To ensure the findings accurately reflect the overall population, all results are weighted using the survey sample weights provided by the NFHS. Furthermore, we use a composite index to identify the principal contributors of RHI. This approach provides a comprehensive understanding of the critical determinants influencing women’s reproductive health in the studied population (23,24,44). Additionally, we conducted bivariate analyses to assess the levels of women’s reproductive health based on the socioeconomic and demographic characteristics of the mother.

RHII= 1nj=1nXij

RHII = Reproductive Health Index score for women i

Xij = Standarised value of reproductive health indicator j for women i

n = Total number of reproductive health indicators

In the next phase, understanding the count form of the interest variable, we utilise the Poisson regression model to examine whether respondents had access to distinct overall well-being.

log(E(RHIi)) = β0+β1CEBi + k=2mβkZik+ ϵi

E(RHIi)= Expected Reproductive Health Index for women i

CEBi = Number of children ever born (Key explanatory variable)

Zik = Vector of socio-economic and demographic control variables

βk = Coefficients for the explanatory variables

ϵi = Error term

This analysis is divided into two main parts. First, we investigate whether having a lower CEB is associated with women’s reproductive health. Second, we explore the association between women’s reproductive health and the CEB while also considering background characteristics. To assess the robustness of the composite index, we conduct a sensitivity analysis by reconstructing the RHI using alternative indicator combinations (RHI2, RHI3, RHI4) and run the Poisson regression models. The results remain consistent and support the reliability of the index (S1 Table).

Before conducting the regression analysis, we tested for multicollinearity among key age-related covariate using the Variance Inflation Factor (VIF). All values are below the standard threshold, indicating that multicollinearity is not a concern. Additionally, we assess for overdispersion using the Pearson chi-square goodness-of-fit test. The dispersion value is close to 1 (χ² = 45,143.74, p = 1.000), indicating no evidence of overdispersion.

We utilise Stata version 17.0 to conduct data analysis. We use ArcMap to create maps. The shapefile used to generate the map is freely available from the official Demographic Health Survey website (https://dhsprogram.com/data/available-datasets.cfm). The map is prepared by the author.

Results

Variation in individual RHI indicators within the country

Table 2 presents an overview of each indicator of women’s well-being in India. Skilled providers, around 90.2 per cent, attend the majority of deliveries. However, 9.8 per cent of deliveries occur without skilled assistance, which highlights both healthcare gaps and the persistence of cultural or personal preferences for home delivery. Similarly, 85.1 per cent of women receive antenatal care from skilled providers, and 14.9 per cent receive no care or care from unskilled providers, indicating potential gaps in access to quality healthcare services. Furthermore, it highlights the significant maternal health challenge, with 74.6 per cent of women reporting experience of stillbirths or miscarriages within this domain (combined percentage of miscarriage, abortion, and stillbirth). This high prevalence underscores persistent challenges in maternal health and suggests the need for enhanced support and interventions. Anemia remains a significant concern despite some progress. However, there is notable progress in addressing anemia, with a considerable proportion of 40.8 per cent of women categorised as not anemic and more than half, 59.3 per cent, of severe, mild, and moderate anemia remaining concerning and warranting continued attention. Regarding BMI distributions, more than half of women fall within the normal range of 60.9 per cent. However, significant proportions of 39.1 are categorised as underweight, overweight, and obese. This diversity in BMI statuses highlights the complexity of nutritional challenges faced by women in India and calls for comprehensive approaches to address both undernutrition and overnutrition. Furthermore, the analysis reveals that 17.7 per cent of children are born with low birth weight, reflecting potential challenges in maternal and child health. Additionally, 24.0 per cent of deliveries occur by cesarean section, suggesting the need for further examination of maternal healthcare practices and interventions.

Table 2. Weighted average percentages of each indicator for women’s reproductive health in India (2019–21).

Background characteristics Percentage (N)
Assistance during delivery
 Unskilled provider/No assistance 9.8% (20,213)
 Skilled provider 90.2% (153,725)
Antenatal care provider
 Unskilled provider/No assistance 14.9% (26,286)
 Skilled provider 85.1% (147,652)
Ever experienced stillbirth/miscarriage
 Yes 74.6% (13,163)
 No 25.4% (4,357)
Anemia
 Others 59.2% (98,116)
 Not anemic 40.8% (69,378)
BMI
 Others 39.1% (62,841)
 Normal 60.9% (106,446)
Birth weight of children
 Low birth weight 17.7% (26,796)
 Normal 82.3% (132,250)
Delivery by caesarean section
 Yes 24.0% (37,265)
 No 76.0% (136,673)

Source: Authors’ calculations using NFHS (2019–2021).

Socio-economic background of RHI

Table 3 presents the mean score of RHI by women’s background characteristics. Women aged 15–24 years report the highest mean score of RHI 4.30, followed by those aged 25–34 (4.29), while women aged 35 and above show a slightly lower mea score (4.12), indicating better overall reproductive health among younger age compared to older age groups. Interestingly, the mean RHI score decreases as age increases, highlighting potential age-related health challenges, cumulative effects of multiple pregnancies, and reduced access to utilisation of maternal health services over time. Reproductive health outcomes improve with delayed marriage and childbearing. Women who married or had their first birth after age 18 report higher mean RHI scores (4.31 and 4.29, respectively) than those who did so earlier. The mean score is found to be higher among general groups (4.26) compared to Scheduled Castes (SC) and Scheduled Tribes (ST). There is a notable disparity in reproductive health among different religious groups, with Muslim women having a lower (4.25) compared to women of other religions. Economic status further influences women’s RHI, with the wealth quintile demonstrating a significantly higher mean score. Women who have media exposure, even if partial, have a higher mean RHI score of 4.34, emphasising the importance of access to information. Furthermore, the Northern region shows the highest mean RHI score (4.42), followed by the Northeastern and Southern regions, whereas the Eastern region reports the lowest (4.09), highlighting persistent challenges. Moreover, women residing in urban areas displayed higher levels of RHI than those in rural areas, highlighting urban-rural inequalities in access to and quality of reproductive healthcare services.

Table 3. Mean RHI by background characteristics among the women aged 15-49 in India (2019–21).

Background characteristics Mean SE [95% Conf.Interval] N
Age
 15-24 4.30 0.00 [4.29-4.31] 56621
 25-34 4.29 0.00 [4.28-4.29] 102183
 35+ 4.12 0.01 [4.10-4.13] 16163
Age at marriage
 <18 4.21 0.00 [4.20-4.22] 56871
 >18 4.31 0.00 [4.30-4.31] 117930
Age at first birth
 <18 4.16 0.01 [4.14-4.18] 19765
 >18 4.29 0.00 [4.28-4.30] 155202
Social Groups
 SC 4.23 0.01 [4.22-4.25] 39633
 ST 4.23 0.01 [4.22-4.25] 17295
 OBC 4.31 0.00 [4.30-4.32] 75241
 Others 4.26 0.01 [4.25-4.27] 34256
Religion
 Hindu 4.28 0.00 [4.28-4.29] 139221
 Muslim 4.25 0.01 [4.24-4.27] 27845
 Christian 4.33 0.02 [4.30-4.37] 3690
 Others 4.13 0.02 [4.10-4.16] 4210
Mass media
 Not Exposed 4.09 0.01 [4.08-4.10] 45992
 Partially exposed 4.34 0.00 [4.34-4.35] 125777
 Exposed 4.29 0.02 [4.26-4.33] 3198
Wealth quintiles
 Poorest 4.06 0.01 [4.05-4.07] 39846
 Poorer 4.29 0.01 [4.28-4.30] 36815
 Middle 4.37 0.01 [4.36-4.38] 34253
 Richer 4.37 0.01 [4.36-4.39] 33652
 Richest 4.32 0.01 [4.31-4.33] 30399
Region
 North 4.42 0.01 [4.41-4.44] 23776
 East 4.09 0.01 [4.08-4.10] 45132
 Northeast 4.38 0.01 [4.36-4.41] 7092
 Central 4.29 0.01 [4.28-4.30] 46634
 West 4.33 0.01 [4.32-4.34] 22609
 South 4.35 0.01 [4.33-4.36] 29724
Residence
 Urban 4.30 0.00 [4.29-4.30] 49346
 Rural 4.27 0.00 [4.26-4.27] 125621

Source: Authors’ calculations using NFHS (2019–2021).

Fig 1 indicates that married women with four or more children tend to have lower mean RHI levels than those with fewer children, particularly those with below replacement levels. This suggests that having fewer children is more favorable for women’s overall health and well-being.

Fig 1. Association between children ever born and Reproductive Health Index (RHI) score.

Fig 1

District-level variation in women’s reproductive health

A district-wise mean score is analysed, and the result is depicted in Fig 2. Among the states, Rajasthan has the highest RHI score, followed by Kerala, Manipur, and Mizoram. In contrast, the lowest RHI score is observed in Jammu and Kashmir, followed by Punjab, Bihar, and Jharkhand. In nearly 15 states and union territories, the RHI score is below 4.35.

Fig 2. District-level spatial distribution in Reproductive Health scoresacross India, 2019–21.

Fig 2

There is no state where the RHI score exceeds 5.25. In the Northern region, except for Jammu and Kashmir and Punjab, most states have moderate scores. On the other hand, in Central India, most of the states have lower levels of women’s RHI, except Chhattisgarh. All states in the Southern region, except Telangana, demonstrate moderate to high RHI scores. Interestingly, the Western states of Maharashtra show a moderate to high score. However, the Eastern and northeastern states exhibit moderate to high RHI scores. Most North Eastern states like Mizoram, Manipur, and Tripura score high, while others secure moderate positions. The Eastern states, like West Bengal, Bihar, and Jharkhand, are notably weak, whereas states like Orissa are in the moderate range. These results indicate that most states should prioritise efforts to enhance women’s reproductive health and improve their overall conditions.

The association between women’s reproductive health and background characteristics

The relationship between women’s reproductive health and low fertility is complex and influenced by multiple background characteristics. The result of the Poisson regression model is presented in Table 4. It reveals a negative association between the number of CEB and reproductive health; women with higher CEB are less likely to have RHI, and the pattern is consistent even after adjusting the women’s socio-economic and demographic characteristics. In Model 1, women with four or more children have significantly lower reproductive health scores than those with fewer children [IRR: 1.00; CI: 0.99, 1.00]. The trend persists in Model 2, even after adjusting for demographic and socio-cultural variables. Women with three or four children have significantly lower RHI scores compared to those with below replacement number of children [IRR: 0.97; CI: 0.96, 0.98]. Model 3 highlights that while the negative association between higher parity and reproductive health remains, mass media exposure and household wealth continue to show positive contributions to women’s reproductive well-being, highlighting their potential role in supporting better health outcomes.

Table 4. Poisson regression results (Incidence Rate Ratios) showing factors associated with women’s reproductive health in India (2019–21).

RHI Score Model 1
IRR with 95% CI
Model 2
IRR 95% CI
Model 3
IRR with 95% CI
CEB
 1
 2 1.00 [0.99,1.00] 1.00 [0.99,1.01] 1.00 [1.00,1.01]
 3 0.99*** [0.98,0.99] 1.00 [0.99,1.01] 1.00 [1.00,1.01]
 4+ 0.95*** [0.94,0.96] 0.97*** [0.96,0.98] 0.98*** [0.97,0.99]
Age
 15-24
 25-34 1.00 [0.99,1.00] 0.99 [0.99,1.00]
 35+ 0.97*** [0.96,0.98] 0.97*** [0.96,0.98]
Age at marriage
 <18
 >18 1.01** [1.00,1.02] 1.01 [1.00,1.01]
Age at first birth
 <18
 >18 1.01** [1.00,1.02] 1.01** [1.00,1.02]
Social Groups
 SC
 ST 1.01 [1.00,1.02] 1.02*** [1.01,1.03]
 OBC 1.02*** [1.01,1.03] 1.01*** [1.01,1.02]
 Others 1.00 [1.00,1.01] 1.00 [0.99,1.01]
Religion
 Hindu
 Muslim 0.99* [0.98,1.00] 0.99 [0.99,1.00]
 Christian 1.00 [0.99,1.01] 0.99 [0.98,1.01]
 Others 0.96*** [0.95,0.98] 0.96*** [0.95,0.97]
Mass media
 Not Exposed
 Partially exposed 1.04*** [1.03,1.05]
 Exposed 1.03** [1.01,1.05]
Wealth quintiles
 Poorest
 Poorer 1.05*** [1.04,1.05]
 Middle 1.06*** [1.05,1.06]
 Richer 1.05*** [1.04,1.06]
 Richest 1.03*** [1.02,1.04]
Region
 North
 East 0.94*** [0.93,0.95] 0.96*** [0.95,0.96]
 Northeast 1.01 [1.00,1.02] 1.01* [1.00,1.02]
 Central 0.98*** [0.97,0.98] 0.99*** [0.98,0.99]
 West 0.98*** [0.97,0.99] 0.98** [0.97,0.99]
 South 0.97*** [0.97,0.98] 0.97*** [0.96,0.97]
Residence
 Urban
 Rural 1.00 [0.99,1.00] 1.00 [1.00,1.01]

Source: Authors’ calculations using NFHS (2019–2021).

Age is also a significant determinant, with older women (aged 35 and above) showing a negative association with RHI compared to younger age groups. Women aged 35 and above are significantly less likely to have higher reproductive health scores compared to those below the age of 24 [IRR: 0.97;CI: 0.96, 0.98]. Furthermore, women who married at 18 years or older have better reproductive health outcomes [IRR: 1.01;CI: 1.00, 1.01], while those who had their first birth at 18 years or older are less likely to have RHI scores [IRR: 1.01; CI: 1.00, 1.02]. Social groups exhibited differences in reproductive health, with ST [IRR: 1.02;CI: 1.01, 1.03] and Other Backward Class (OBC) [IRR: 1.01;CI: CI: 1.01, 1.02] being less likely to achieve high reproductive health compared to the general population. Religion affiliations also play a role, with Christians and individuals in the Others category having negative associations with RHI compared to Hindus. Mass media exposure and household wealth demonstrated a positive association with women’s reproductive health. Women across wealth categories, from poorer [IRR: 1.05;CI: 1.04, 1.05] to richer [IRR: 1.05;CI: 1.04, 1.06], show better reproductive health outcomes. Partial exposure to mass media is significantly associated with higher RHI scores [IRR: 1.04;CI: 1.03, 1.05], indicating the importance of media in promoting reproductive health awareness. The Northeastern region shows a positive coefficient relative to the Northern region, though the association is not significant after adjustment. Lastly, RHI scores do not differ significantly between rural and urban areas in model 3.

Discussion

The present study investigates the impact of declining fertility rates on women’s reproductive health in India using the latest data from NFHS (2019–2021). The study reveals a negative association between having more children and RHI scores. Regression results also reflect a similar pattern, even after controlling for the demographic and social characteristics of the women. This result aligns with prior research indicating that higher parity often correlates with adverse health outcomes. For instance, studies have shown that having more children can increase the physical, emotional, and economic burdens on women [33,37,39,40]. Lower fertility rates can reduce these burdens, leading to better health outcomes and overall well-being [41]. However, this study uniquely highlighted that the benefits of low fertility are not uniformly distributed across all socio-economic and demographic groups in India.

The observed trends in antenatal care highlight the disparity in access to quality healthcare services, with a notable proportion of women receiving no antenatal care or care from unskilled providers. This is consistent with previous studies that have highlighted the inequalities in maternal health services in different groups [44]. In the same way, a substantial proportion of deliveries are attended by unskilled providers or without assistance. These findings underscore the importance of enhancing healthcare infrastructure and accessibility to ensure comprehensive maternal and reproductive health services for women nationwide [45].

The persistent challenges in maternal health and nutrition are evident from the high prevalence of stillbirths, miscarriages, and anemia among women. This aligns with previous studies indicating that adverse pregnancy outcomes are often linked to inadequate prenatal care and socioeconomic disparities [46,47]. Despite progress in addressing anemia, the study highlights the continued prevalence of moderate and mild cases. Previous research shows that anemia is often linked to poor dietary intake, high fertility rates, and low socioeconomic status of women [48]. Addressing anemia requires comprehensive nutritional interventions and improved healthcare services.

The diversity of BMI distributions reflects the complex nutritional challenges women face in India, necessitating comprehensive approaches to address both undernutrition and overnutrition. Previous studies have highlighted the dual burden of malnutrition in India [42,49,50]. The prevalence of low birth weight among children highlights significant concerns in maternal and child health, which are often associated with inadequate maternal nutrition and healthcare during pregnancy [51]. The relatively high rate of caesarean deliveries suggests the need for further examination of maternal healthcare practices and potential over-medicalisation of childbirth, which has been observed in other studies as well [52].

Furthermore, the analysis reveals negative associations between women’s reproductive health and various demographic and socio-economic factors such as older age, early marriage, and higher parity, highlighting the importance of reproductive choices and healthcare access. Disparities based on social groups, religion, media exposure, wealth quintiles, and regional variations underscore the need for targeted interventions to address inequalities and promote women’s reproductive health status. Notably, some districts in the Northeastern region report higher RHI scores despite socio-economic disadvantages, reflecting stronger community engagement in maternal care, particularly in tribal and ethnic regions where cultural practices and outreach-based health services contribute positively to reproductive health [41]. The regression analysis reveals that rural residency negatively affects women’s reproductive health, but this factor can be mitigated by economic well-being and media exposure. In rural India, nearly half of the women did not have regular exposure to any form of media, whereas in urban areas, it was less [11]. Rural women have less exposure to mass media, emphasising the need for targeted interventions to improve healthcare access, enhance nutritional status, and address socio-economic disparities.

Therefore, the findings emphasise the importance of holistic approaches to address the complex interplay of factors influencing women’s reproductive health and overall well-being. Targeted interventions to improve healthcare access, enhance nutritional status, and address socio-cultural disparities are essential for promoting gender equality and fostering sustainable development in India. By integrating these insights into policy formulation and program design, policymakers and stakeholders can work towards ensuring their rights to health and well-being.

Limitations and strengths of the study

This study has some limitations that need to be acknowledged. Firstly, the cross-sectional design of the DHS and NFHS data limits the ability to find a causal relationship between fertility levels and reproductive health outcomes. While cross-sectional data allows for identifying association, the temporal effects cannot be firmly established. Secondly, some of the variables are self-reported data, which may introduce recall and reporting bias. Thirdly, despite the controlling for numerous socio-economic and demographic factors, the unmeasured confounding factors such as cultural norms and informal healthcare practices may influence the result.

Despite these limitations, the study has several strengths. It uses nationally representative data from NFHS-5 to ensure that the findings are robust and enhance the reliability of the results. Moreover, the study adopts the capability approach, health inequity and life cycle approach to understand the disparities across socio-economic, demographic, and regional groups. Finally, the study’s policies focus on the vulnerable groups and equity issues and offer critical insights for targeted interventions. These findings inform policies that promote the improvement of reproductive health, gender equality, and sustainable societal development in India’s diverse socio-cultural landscape.

Conclusions and policy implications

The findings of this study provide a critical foundation for understanding the relationship between fertility transitions and women’s reproductive health in India, emphasising the significant variations across different socio-economic and demographic groups that influence health outcomes. While fertility transition in India is associated with improved maternal health, the benefits remain unequally distributed, particularly among disadvantaged backgrounds, including those from SC, ST and economically weaker populations. Women from higher socio-economic backgrounds and urban areas tend to experience more substantial improvements in their reproductive health, whereas those from lower socio-economic groups and rural areas face persistent challenges. Additionally, the study highlights the importance of considering regional variations in health policies to ensure that the benefits of lower fertility are accessible to women across diverse settings in India.

Addressing these disparities requires a comprehensive policy approach that strengthens healthcare infrastructure, ensures equitable access to maternal healthcare services, and enhances reproductive health awareness. A key policy should be taken to improve healthcare access in underperforming regions by expanding the availability of skilled birth attendants, integrating mobile health units in backward rural areas, and promoting telemedicine-based consultations for antenatal and postnatal care. Additionally, conditional cash transfer like Janani Suraksha Yojana (JSY) can increase the institutional delivery and be linked to antenatal care visit, can incentivise utilisation of maternal health services among low income groups. Strengthening nutritional support programs is essential to reduce anemia, malnutrition and low birth weight through food fortification policies, iron and folic acid supplementation, and maternal nutrition counseling. Additionally, the overuse of cesarean deliveries in private healthcare must be regulated through governmental policies, and the number of midwife-led birthing centers must be increased to encourage safe childbirth practices. Expanding the role of community health workers to engage with these populations can further enhance service utilisation and awareness regarding reproductive health services. Simultaneously, state-led mass media campaigns are essential to improve birth spacing, contraceptive use, and safe delivery practices and also increase reproductive health awareness.

This research contributes to the broader discourse on fertility management and reproductive health by emphasising the importance of ensuring women’s health and well-being. Aligning these efforts with SDG goals, especially SDG 3 (Good Health and Well-being) and SDG 5 (Gender Equality), will be essential to promote gender-responsive health policies. Addressing all the constraints and enhancing equitable healthcare access for all will be essential for translating the benefits of low fertility into improved reproductive health and broader societal development.

Supporting information

S1 Table. Sensitivity analysis using Poisson regression models based on alternate Reproductive Health Index (RHI) specifications.

(DOCX)

pone.0329375.s001.docx (13.9KB, docx)

Acknowledgments

This paper was presented at the 35th International Geographical Congress (IGC), 2024, in Dublin, Ireland. We are grateful for the valuable feedback received from experts during the conference, which has been incorporated into this study and has significantly improved the quality of the manuscript. We thank the anonymous reviewers for their valuable comments and constructive feedback, which significantly improved the clarity and quality of the paper.

Data Availability

The dataset used in this study are publicly available and can be accessed from DHS Program: https://dhsprogram.com/. Any researcher can access this dataset from DHS after registering at: https://dhsprogram.com/data/new-user-registration.cfm and get permission to access the data at: https://dhsprogram.com/data/dataset/India_Standard-DHS_2020.cfm?flag=1.

Funding Statement

The author(s) received no specific funding for this work.

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Decision Letter 0

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10 Mar 2025

PONE-D-25-01359-->-->Does Low Fertility Indicate Better Reproductive Health Status? Evidence from Nationally Representative Survey in India-->-->PLOS ONE?>

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Reviewers' comments:

Reviewer's Responses to Questions

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1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: Yes

Reviewer #4: No

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2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

Reviewer #4: Yes

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The PLOS Data policy

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Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

Reviewer #4: Yes

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Reviewer #1: The paper has novelty and significance in respect to current women health condition in India. But this paper has been analysed and written very well but it has some structural problem that need to improve for better readability of the paper. Here are my following suggestions.

1.Line 45: The authors have written (coefficient = -0.05; CI: -0.06, -0.05), what is the relevance of these values in abstract, I would suggest to remove the values from abstract and only focus on the outcome of analysis.

2.I do not feel the necessary of separate Introduction and Fertility Transition and Reproductive Health section, rather I would suggest to integrate them and strengthen the background of the study.

3.Do you really need this sentence in line 162-163- “The International Institute for Population Sciences (IIPS) in Mumbai conducted the survey with funding from the Government of India's Ministry of Health and Family Welfare”. I don’t feel so. Similar for line 166-167. Streamline the line 161-168, and remove unnecessary lines.

4.After reading the whole methodology I feel that it needs to rearrange, as my previous comment, remove unnecessary writing for data, sample size and Variables and their measurement section. Combine them together in one section, and named the section- ‘study variables, measurements and sources’ something like that. Then in that section first paragraph write data source and samples, then onwards variable measurements.

5.Line 215: Do you want to cite STATA, if not then what is the need for writing this-(Stata Corporation, College Station, TX), as you already stated that you used STATA 17.

6.I would Like to give citation or equation in like 202-206

7.-I would like to give regression equation forms of two poison regression.

8.Line 2015-2017- you wrote that “We use ArcMap for creating maps. The shape file for the maps is downloaded from the official Demographic Health Survey (https://dhsprogram.com/data/available-datasets.cfm) website”. If you really feel that you need to mentioned this, concise the sentences.

9.In table 1: what is the meaning of given two collum for category ? instead you simple in one column, write category and in bracket yes/no (category (yes/no)), is not it represent the same as you did. Think. What you did makes the paper structure unesthetic and reader will lose the concentration while reading.

10.Table 2: similar problem like table one, you can simple write totalvalue and % in bracket- 20,213 (9.8).

11.I do not understand the meaning of “No one” in table 2, can you clarify and reframe.

12.In table 2. For Ever experienced Still Birth/miscarriage- you have written separate percentage for yes and for no, together 100%. Then what is the meaning of given both yes and no, if 74.56 % is for yes, then rest of the % will by default become no. can you explain?

13.In line 246- you write a heading of a section “Mean number of RHI in background characteristics-wise”, I won’t do that, mean is the analysis you did, it doesnot represent the content of the section. Rather write “socio-economic/ecological/political/cultural background of RHI”

14.Which one is figure 1?, author should have basic responsibility to frame the paper.

15.I don’t feel the necessity of writing composite score in the title “District-level Variation in Women’s Reproductive Health Composite Score”

16.Where is figure 2 ?

17.Table 4, what the value inside table represents? standard error? or coefficient? or something else. How do I know? This reflects the lack of professionalism by the authors. I would suggest to follow good article, and carefully check how they represent the regression table in the paper.

18.Your policy suggestions are too generals, based on your study, What policy measure will you take if you become the sole responsible authority.

19.Overall, I feel paper is lengthy, and some part of the writing is exaggerated and over romanticised.

Over all paper is interesting, I feel this structural change make the paper more concise and increase the understandability and readability of the non-subject readers also. I recommend the paper for above minor, not major revision.

Reviewer #2: The manuscript presents a rigorously conducted study characterised by a high level of technical competence. The data is robust, and the conclusions drawn are substantiated by the experiments and analyses executed. The statistical analysis is both appropriate and comprehensive, which enhances the reliability of the findings and their interpretation. Furthermore, the authors have made all underlying data available in accordance with PLOS Data policies, thereby ensuring transparency. The manuscript is well-structured and articulately written in standard English, rendering the content both accessible and easily comprehensible.

Reviewer #3: This cross-sectional study attempts to explore the association between declining fertility rates and women's reproductive health in India, considering socioeconomic and demographic factors as well as regional variations. The objective of this paper is quite relevant & interesting, but has some shortcomings which needs major revisions & rework. Hence, upon preliminary review, my recommendation is for a major revision before considering the manuscript for publication.

Followings are some of my observations that needs further clarification and revision:

1.The article requires substantial revision to address grammatical problems and repetitive sentences (e.g., lines 355-359). Furthermore, the article appears to be very lengthy, and the assertions in the findings, discussions, and conclusion sections are very repeated.

2.Line no. 106-107: ‘By integrating these …….low fertility on holistic well-being”. I have a serious concern in using the term ‘holistic well-being of women’ which can include both mental and social well-being as well (as the author mentioned in 99-101). But in the analysis, there are no indicators on social or mental well being of women. As a result, it is better to avoid using this term or to explain how your seven indicators can justify mental and social well-being.

3.Line no. 224-25: ‘However, 9.78% of deliveries ……remains insufficient.’ Lower percentages of deliveries by skilled persons does not always imply lower access to health care facilities. What about the families who don’t opt for such deliveries and prefer delivery at home?

4.Line no. 258-259: ‘Regarding regional variations…..RHI’. Even northern regions have highest mean RHI (4.42). But the author doesn’t mention that. Additionally, interpretation of regression mentioned (in line no. 316-318) north-eastern region showing lower likelihood of RHI, while the values are positive. Please rework and rewrite the section.

5.In some cases, the OR values are very low. Plus, the author needs to mention the high or low RHI score range as the scores does not vary much (such as 4.33 in West and 4.35 in South). Please elaborate on how far it is justified to say that regional disparities exist (line 316-318)?

6.Line 318-319: ‘Additionally, residence plays…. counterparts (Model 3)’. In model 3 Rural and urban odds are not significant. Therefore, no difference between rural and urban areas.

7.Line 297-300: ‘Model 3 highlights….wealth index’. Please elaborate, as the models do not show that.

8.Please recheck the Poisson regression model. Odds ratio can’t be negative. An odds ratio greater than 1 indicates an increased risk associated with the exposure, while an odds ratio less than 1 indicates a decreased risk. Do the values in Table 4 represent odds or log odds? If log odds, then the interpretation should alter.

9.The author tries to investigate the spatial variation. What about the role of clustering effect on depended variable due to hierarchical nature of NFHS data? Can Poisson regression model consider that effect?

Reviewer #4: 1.The title of the paper does not reflect the analysis presented; the author does not analyse low fertility but rather focuses on the factors associated with women’s reproductive health.

2.The abstract of the paper does not follow the journal's format.

3.The introduction section does not clearly mention the research gap and the objective of the paper.

4.The concept of the Reproductive Health Index (RHI) is not clearly defined in the introduction. The benefits and how NFHS data can be used to measure this index should be explained more clearly.

5.The limitations of the paper should be included in the discussion section, not the introduction section.

6.The justification for using the Poisson regression model should be clarified, especially over other models such as the negative binomial regression.

7.The justification for the equal weighting of indicators in the RHI should be explained. The author could conduct a sensitivity analysis to support this approach.

8.The Northeastern region is associated with higher RHI scores despite socioeconomic disadvantages; this finding needs more discussion.

**********

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Reviewer #1: No

Reviewer #2: Yes:  Papai Barman

Reviewer #3: No

Reviewer #4: No

**********

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Attachment

Submitted filename: Comments.docx

pone.0329375.s002.docx (16.4KB, docx)
Attachment

Submitted filename: plosone_review.docx

pone.0329375.s003.docx (17.1KB, docx)
PLoS One. 2025 Aug 12;20(8):e0329375. doi: 10.1371/journal.pone.0329375.r002

Author response to Decision Letter 1


12 Apr 2025

Reviewer #1: The paper has novelty and significance in respect to current women health condition in India. But this paper has been analysed and written very well but it has some structural problem that need to improve for better readability of the paper. Here are my following suggestions.

Reply: We are sincerely grateful for the time and efforts for the reviews of our manuscript, “Does Low Fertility Indicate Better Reproductive Health Status? Evidence from Nationally Representative Survey in India.” We appreciate the constructive feedback, which has helped us to strengthen the manuscript significantly.

Comment 1. Line 45: The authors have written (coefficient = -0.05; CI: -0.06, -0.05), what is the relevance of these values in abstract, I would suggest to remove the values from abstract and only focus on the outcome of analysis.

Reply: Thank you. We have removed the coefficient values and retained only the outcomes in the abstract.

Comment 2. I do not feel the necessary of separate Introduction and Fertility Transition and Reproductive Health section, rather I would suggest to integrate them and strengthen the background of the study.

Reply: We appreciate this suggestion. These sections have been merged and the background has been strengthened (see lines 97–120 and 137–139).

Comment 3. Do you really need this sentence in line 162-163- “The International Institute for Population Sciences (IIPS) in Mumbai conducted the survey with funding from the Government of India's Ministry of Health and Family Welfare”. I don’t feel so. Similar for line 166-167. Streamline the line 161-168, and remove unnecessary lines.

Reply: Thank you for this suggestion. We addressed this comment and removed all the lines from the data as suggested.

Comment 4. After reading the whole methodology I feel that it needs to rearrange, as my previous comment, remove unnecessary writing for data, sample size and Variables and their measurement section. Combine them together in one section, and named the section- ‘study variables, measurements and sources’ something like that. Then in that section first paragraph write data source and samples, then onwards variable measurements.

Reply: Addressed. We have created a two section titled Data Sources and Study Variables and their Measurements, combining the data, variables, and source sections.

Comment 5. Line 215: Do you want to cite STATA, if not then what is the need for writing this-(Stata Corporation, College Station, TX), as you already stated that you used STATA 17.

Reply: Thank you for this suggestion. The citation has been removed.

Comment 6. I would Like to give citation or equation in like 202-206

Reply: We have added the composite index equation and appropriate citations (see lines 180–183).

Comment 7. I would like to give regression equation forms of two poison regressions.

Reply: Thank you for this suggestion. We have addressed the comment and added a regression equation in the methodology section (lines 186-191).

Comment 8. Line 2015-2017- you wrote that “We use ArcMap for creating maps. The shape file for the maps is downloaded from the official Demographic Health Survey (https://dhsprogram.com/data/available-datasets.cfm) website”. If you really feel that you need to mentioned this, concise the sentences.

Reply: Addressed. The sentence has been shortened, and the data source part has been removed.

Comment 9. In table 1: what is the meaning of given two column for category ? instead you simple in one column, write category and in bracket yes/no (category (yes/no)), is not it represent the same as you did. Think. What you did makes the paper structure unesthetic and reader will lose the concentration while reading.

Reply: Thank you for your valuable feedback. We acknowledge that having two separate columns for categories may affect the readability of the table. Based on your suggestion, we have reformatted Table 1 with a single column for each variable with values (Yes/No) to improve readability and aesthetics.

Comment 10. Table 2: similar problem like table one, you can simple write total value and % in bracket- 20,213 (9.8).

Reply: Thank you for your comment. We have deleted the second percentage column and merged the total values and percentages into a single column (e.g., 20,213 (9.8%)) to improve readability and ensure consistency across all categories.

Comment 11. I do not understand the meaning of “No one” in table 2, can you clarify and reframe.

Reply: We have replaced “No one” with “Unskilled provider/No assistance” to clarify that this category includes cases where women either received assistance from an unskilled provider or had no assistance.

Comment 12. In table 2. For Ever experienced Still Birth/miscarriage- you have written separate percentage for yes and for no, together 100%. Then what is the meaning of given both yes and no, if 74.56 % is for yes, then rest of the % will by default become no. can you explain?

Reply: We appreciate this comment. We have removed the “No” row and retained only the 'Yes' category. A footnote has been added for clarity.

Comment 13. In line 246- you write a heading of a section “Mean number of RHI in background characteristics-wise”, I won’t do that, mean is the analysis you did, it does not represent the content of the section. Rather write “socio-economic/ecological/political/cultural background of RHI”

Reply: We have removed the line Mean number of RHI and addressed this comment by adding the ‘Socio-economic background of RHI’.

Comment 14. Which one is figure 1?, author should have basic responsibility to frame the paper.

Reply: Thank you for your suggestion. Figures are provided separately in TIFF format as per journal submission guidelines.

Comment 15. I don’t feel the necessity of writing composite score in the title “District-level Variation in Women’s Reproductive Health Composite Score”

Reply: The title has been revised as suggested.

Comment 16. Where is figure 2?

Reply: The figure is provided separately in the TIFF file as per the journal’s guidelines.

Comment 17. Table 4, what the value inside table represents? standard error? or coefficient? or something else. How do I know? This reflects the lack of professionalism by the authors. I would suggest to follow good article, and carefully check how they represent the regression table in the paper.

Reply: Thank you for this suggestion. The table now included coefficients and confidence intervals.

Comment 18. Your policy suggestions are too generals, based on your study, What policy measure will you take if you become the sole responsible authority.

Reply: The policy implication section has been revised to reflect precise and actionable recommendations derived from the findings of the study.

Comment 19. Overall, I feel paper is lengthy, and some part of the writing is exaggerated and over romanticised.

Reply: Thank you. We have revised the introduction and reduced redundancy to improve conciseness.

Over all paper is interesting, I feel this structural change make the paper more concise and increase the understandability and readability of the non-subject readers also. I recommend the paper for above minor, not major revision.

Reply: Thank you. The manuscript has been revised accordingly for enhanced readability and organisation.

Reviewer #2: The manuscript presents a rigorously conducted study characterised by a high level of technical competence. The data is robust, and the conclusions drawn are substantiated by the experiments and analyses executed. The statistical analysis is both appropriate and comprehensive, which enhances the reliability of the findings and their interpretation. Furthermore, the authors have made all underlying data available in accordance with PLOS Data policies, thereby ensuring transparency. The manuscript is well-structured and articulately written in standard English, rendering the content both accessible and easily comprehensible.

Reply: Thank you for your supportive feedback. We appreciate your positive evaluation.

Reviewer #3: This cross-sectional study attempts to explore the association between declining fertility rates and women's reproductive health in India, considering socioeconomic and demographic factors as well as regional variations. The objective of this paper is quite relevant & interesting, but has some shortcomings which needs major revisions & rework. Hence, upon preliminary review, my recommendation is for a major revision before considering the manuscript for publication.

Reply: We sincerely thank the reviewer for acknowledging the relevance and importance of our study. We have carefully addressed all suggested revisions to improve the clarity, structure, and interpretation. We hope the revised manuscript meets the expectations for further consideration.

Followings are some of my observations that needs further clarification and revision:

Comment 1. The article requires substantial revision to address grammatical problems and repetitive sentences (e.g., lines 355-359). Furthermore, the article appears to be very lengthy, and the assertions in the findings, discussions, and conclusion sections are very repeated.

Reply: Thank you for your observation. We have thoroughly revised the manuscript to correct grammatical errors and improve clarity. We have deleted the repetitive sentences from the findings and discussion.

Comment 2. Line no. 106-107: ‘By integrating these …….low fertility on holistic well-being”. I have a serious concern in using the term ‘holistic well-being of women’ which can include both mental and social well-being as well (as the author mentioned in 99-101). But in the analysis, there are no indicators on social or mental well being of women. As a result, it is better to avoid using this term or to explain how your seven indicators can justify mental and social well-being.

Reply: We agree with the concern. The phrase “holistic well-being” has been replaced with more precise terms, such as “reproductive health,” in relevant sections to maintain objectivity.

Comment 3. Line no. 224-25: ‘However, 9.78% of deliveries ……remains insufficient.’ Lower percentages of deliveries by skilled persons does not always imply lower access to health care facilities. What about the families who don’t opt for such deliveries and prefer delivery at home?

Reply: Thank you for this important observation. We agree that lower rates of skilled delivery attendance may not always reflect limited access to healthcare services. Cultural preferences, traditional beliefs, and personal choices can also influence the decision to deliver at home without skilled assistance. To address this, we have revised the statement to acknowledge that while the proportion of unskilled deliveries may indicate service gaps, it may also reflect the voluntary preference for home births in certain communities.

Comment 4. Line no. 258-259: ‘Regarding regional variations…..RHI’. Even northern regions have highest mean RHI (4.42). But the author doesn’t mention that. Additionally, interpretation of regression mentioned (in line no. 316-318) north-eastern region showing lower likelihood of RHI, while the values are positive. Please rework and rewrite the section.

Reply: Thank you for the comment. You are correct that the Northern region shows the highest mean RHI score in the descriptive analysis. However, the difference between the North and North Eastern regions becomes statistically insignificant in the regression after adjusting for covariates. Therefore, we rely on the descriptive means for interpretation in this case. Also, we rewrite the section mentioned above.

Comment 5. In some cases, the OR values are very low. Plus, the author needs to mention the high or low RHI score range as the scores does not vary much (such as 4.33 in West and 4.35 in South). Please elaborate on how far it is justified to say that regional disparities exist (line 316-318)?

Reply: Thank you for pointing this out. We have corrected the earlier error where coefficients were mistakenly referred to as odds ratios. These are now properly labeled as Poisson regression coefficients. As for the regional variation, we have included the actual RHI score range (4.09 to 4.42) in the results for clarity. Since the difference is slight and the North Eastern region’s coefficient is not statistically significant, to avoid overstatement, we removed the line referencing regional disparities.

Comment 6. Line 318-319: ‘Additionally, residence plays…. counterparts (Model 3)’. In model 3 Rural and urban odds are not significant. Therefore, no difference between rural and urban areas.

Reply: Thank you for pointing this out. We agree that the difference between rural and urban residence is not statistically significant in Model 3. We have revised the sentence in the results section.

Comment 7. Line 297-300: ‘Model 3 highlights….wealth index’. Please elaborate, as the models do not show that.

Reply: Thank you for this helpful observation. We agree that the original interpretation overstated the role of mass media and wealth index in mitigating the effects of higher parity. We have revised the sentence to reflect the results of Model 3 more accurately.

Comment 8. Please recheck the Poisson regression model. Odds ratio can’t be negative. An odds ratio greater than 1 indicates an increased risk associated with the exposure, while an odds ratio less than 1 indicates a decreased risk. Do the values in Table 4 represent odds or log odds? If log odds, then the interpretation should alter.

Reply: Thank you for pointing this out. You are absolutely correct; odds ratios cannot be negative. In the original manuscript, we mistakenly referred to Poisson regression coefficients as odds ratios (OR), which was inaccurate. The values presented in Table 4 are actually log-linear coefficients, not odds ratios. We have corrected the terminology throughout the results and discussion sections. All interpretations have been revised accordingly to reflect the direction and magnitude of association in terms of coefficients, not ORs.

Comment 9. The author tries to investigate the spatial variation. What about the role of clustering effect on depended variable due to hierarchical nature of NFHS data? Can Poisson regression model consider that effect?

Reply: Thank you for your comment. It is also true that NFHS has used multistage stratified clustering sampling; it already adjusted the hierarchical nature of the dataset using the design effect. Therefore, I believe that the use of Poisson regression in this dataset is suitable.

Reviewer #4: 1. The title of the paper does not reflect the analysis presented; the author does not analyse low fertility but rather focuses on the factors associated with women’s reproductive health.

Reply: Thank you for your feedback. We agree that the analysis primarily focuses on women's reproductive health, but this is intentionally framed within the broader context of India's ongoing fertility transition. The study aims to explore how reproductive health outcomes are shaped during a period of declining fertility, which justifies the use of “low fertility” in the title. We believe the current title captures the thematic intent of the paper and its relevance to the demographic shift under study.

Comment 2. The abstract of the paper does not follow the journal's format.

Reply: Thank you for your observation. We have revised the abstract into different sections, such as the introduction, methods, results, and conclusion.

Comment 3. The introduction section does not clearly mention the research gap and the objective of the paper.

Reply: Thank you for your comment. We have revised the introduction to clearly state the research gap and objectives of the paper. This has been addressed in lines 125-132 of the revised manuscript.

Comment 4. The concept of the Reproductive Health Index (RHI) is not clearly defined in the introduction. The benefits and how NFHS data can be used to measure this index should be explained more clearly.

Reply: Thank you for this helpful comment. We have now clarified the concept of the Reproductive Health Index (RHI) in the introduction (128-130). A more detailed explanation of the selected NFHS indicators and how the index is constructed is provided in the methodology sec

Attachment

Submitted filename: Response to Reviewers.docx

pone.0329375.s004.docx (24.3KB, docx)

Decision Letter 1

Pijush Kanti Khan

1 Jul 2025

PONE-D-25-01359R1-->-->Does Low Fertility Indicate Better Reproductive Health Status? Evidence from Nationally Representative Survey in India-->-->PLOS ONE?>

Dear Dr. Sikdar,

Thank you for submitting your manuscript to PLOS ONE. After careful consideration, we feel that it has merit but does not fully meet PLOS ONE’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by Aug 15 2025 11:59PM. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at plosone@plos.org . When you're ready to submit your revision, log on to https://www.editorialmanager.com/pone/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

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We look forward to receiving your revised manuscript.

Kind regards,

Pijush Kanti Khan, Ph.D.

Academic Editor

PLOS ONE

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Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments:

Dear Authors,

Thank you for your revised manuscript. The paper has substantially improved after the revision, and I appreciate the effort you’ve put into addressing the earlier comments. That said, I believe there are still a few minor issues that need to be addressed before the paper is ready for publication. Therefore, I would like to request a minor revision. Please revise the manuscript accordingly and resubmit it by 15th July, 2025. Feel free to reach out if you have any questions or need further clarification. Thank you,

Best regards

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #3: All comments have been addressed

Reviewer #4: (No Response)

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2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #3: Yes

Reviewer #4: No

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #3: Yes

Reviewer #4: I Don't Know

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #3: Yes

Reviewer #4: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #3: Yes

Reviewer #4: No

**********

Reviewer #3: The article addresses a crucial aspect of women's reproductive health and its association with low fertility rates in India. This topic remains relatively underexplored, making the study particularly relevant in the Indian context. After an initial round of revisions, the manuscript is now well-organized and clearly written. The following are some minor suggestions that may further improve clarity:

1. Kindly assess the level of multicollinearity—particularly among variables such as age, age at marriage, and age at first birth—prior to conducting the regression analysis, and include the findings in the manuscript.

2. Please examine the potential presence of endogeneity, as certain variables used in constructing the Reproductive Health Index (e.g., history of stillbirth/miscarriage, type of delivery assistance) may influence the number of children ever born (CEB). A rationale for the absence of endogeneity in the analysis should be provided.

3. Specify the states included in each of the six regional categories, or cite the source from which the regional classification was derived.

4. In the methodology section, please justify the use of the Poisson regression model. Also, check for the presence of overdispersion or under dispersion in the data and report the findings.

5. It is recommended to present Relative Risk Ratios (RRR) in Poisson regression results instead of regression coefficients for clearer interpretation of the results.

6. Ensure that all figures have appropriate titles and are properly numbered.

Reviewer #4: 1.The introduction section includes limited literature; the authors need to add more recent studies.

2.The authors should provide more information about the NFHS data, including the questions asked, which questions were used in this study, and the topics covered by NFHS.

3. The study variables and their measurement methods require further details.

4.In Table 2, the authors report that 75% of respondents have ever experienced a stillbirth or miscarriage. This figure appears inaccurate, as the NFHS report indicates only 7.3% for miscarriage and 0.9% for stillbirth. The authors should verify these figures.

5.In Table 3, the mean RHI varies by women’s age, age at first marriage, and age at first birth. While RHI increases with higher age at first marriage and first birth, it appears to decrease with advancing age of women. This pattern needs further explanation from the authors to clarify the underlying reasons.

**********

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Reviewer #3: No

Reviewer #4: No

**********

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PLoS One. 2025 Aug 12;20(8):e0329375. doi: 10.1371/journal.pone.0329375.r004

Author response to Decision Letter 2


4 Jul 2025

Reviewer #3: The article addresses a crucial aspect of women's reproductive health and its association with low fertility rates in India. This topic remains relatively underexplored, making the study particularly relevant in the Indian context. After an initial round of revisions, the manuscript is now well-organized and clearly written. The following are some minor suggestions that may further improve clarity:

Reply: Thank you very much for your encouraging feedback and for acknowledging the relevance and clarity of our revised manuscript. We sincerely appreciate your constructive suggestions and have carefully considered each of them to further improve the clarity and overall quality of the paper.

Comment 1. Kindly assess the level of multicollinearity—particularly among variables such as age, age at marriage, and age at first birth—prior to conducting the regression analysis, and include the findings in the manuscript.

Reply: Thank you for your valuable suggestion. We have assessed multicollinearity among the key age-related variables (age, age at marriage, and age at first birth) using the Variance Inflation Factor (VIF). All values were below 5 (VIF range: 1.02–3.54), indicating no major multicollinearity concern. This information has been included in the revised methodology section.

Comment 2. Please examine the potential presence of endogeneity, as certain variables used in constructing the Reproductive Health Index (e.g., history of stillbirth/miscarriage, type of delivery assistance) may influence the number of children ever born (CEB). A rationale for the absence of endogeneity in the analysis should be provided.

Reply: Thank you for this valuable comment. We agree that certain indicators, such as history of miscarriage or type of delivery assistance, may conceptually influence or be influenced by fertility behaviours. To address this, we conducted a sensitivity analysis using alternate specifications of the Reproductive Health Index (RHI), including versions that exclude these potentially endogenous components. The results remained consistent in direction and significance, suggesting that any endogeneity is unlikely to meaningfully bias the findings. As this assessment is already reflected in our supplementary analysis (see S1 Table), we have not added a separate discussion in the manuscript.

Comment 3. Specify the states included in each of the six regional categories, or cite the source from which the regional classification was derived.

Reply: Thank you for this suggestion. We have now specified the states included in each of the six regional categories in the Methodology section of the revised manuscript.

Comment 4. In the methodology section, please justify the use of the Poisson regression model. Also, check for the presence of overdispersion or under dispersion in the data and report the findings.

Reply: Thank you for the suggestion. While the rationale for using the Poisson model was already included in the methodology section, we have now tested for overdispersion using the Pearson chi-square goodness-of-fit test. The dispersion statistic was close to 1 (χ² = 45,143.74, p = 1.000), indicating that the Poisson model is well-suited. This clarification has been added to the revised manuscript.

Comment 5. It is recommended to present Relative Risk Ratios (RRR) in Poisson regression results instead of regression coefficients for clearer interpretation of the results.

Reply: Thank you for this suggestion. We have now updated Table 4 and the associated text to report exponentiated Poisson regression results, presenting Incidence Rate Ratios (IRRs) for clearer interpretation. This change enhances the readability and understanding of the model outputs.

Comment 6. Ensure that all figures have appropriate titles and are properly numbered.

Reply: Thank you for your suggestion. We have addressed this comment by ensuring that all figures are now properly numbered Fig 1 and Fig 2 and consistently cited in the manuscript.

Reviewer #4: 1. The introduction section includes limited literature; the authors need to add more recent studies.

Reply: Thank you for your valuable suggestion. We have now revised the Introduction section to include more literature.

Comment 2. The authors should provide more information about the NFHS data, including the questions asked, which questions were used in this study, and the topics covered by NFHS.

Reply: Thank you for this valuable comment. In response, we have elaborated on the NFHS data structure, the specific women’s module used, and the variables selected for this study. We now provide greater detail on the questions informing each reproductive health indicator. These clarifications have been added to the Data Sources and Study Variables and Their Measurement.

Comment 3. The study variables and their measurement methods require further details.

Reply: Thank you for your thoughtful comment. We would like to note that the detailed definitions, coding schemes, and rationale for all the variables included in the analysis are presented in Table 1 of the manuscript. This table outlines how each component of the Reproductive Health Index (RHI) is derived from the NFHS-5 data, ensuring transparency and replicability. We have also reviewed the surrounding text to ensure it appropriately references and explains the variables where needed.

Comment 4. In Table 2, the authors report that 75% of respondents have ever experienced a stillbirth or miscarriage. This figure appears inaccurate, as the NFHS report indicates only 7.3% for miscarriage and 0.9% for stillbirth. The authors should verify these figures.

Reply: Thank you for this insightful comment. We have carefully reviewed this issue and would like to clarify that our estimate is based on a subsample of currently married women aged 15–49 who had at least one birth in the five years preceding the survey, rather than all women of reproductive age. This differs methodologically from the NFHS-5 national report, which calculates the prevalence of stillbirth and miscarriage across the entire sample of surveyed women. Furthermore, our operationalisation of the variable “ever experienced stillbirth/miscarriage” includes only stillbirth and miscarriage, and excludes abortion, in line with the focus of our Reproductive Health Index (RHI) on involuntary and health-related pregnancy losses. Including abortion, a decision that is often voluntary would not align with the conceptual objective of the index and might misrepresent the reproductive health burden the index is intended to capture. We have clearly noted this in the main text of the Methods section and a footnote has been included below Table 1 to reinforce this decision.

Comment 5. In Table 3, the mean RHI varies by women’s age, age at first marriage, and age at first birth. While RHI increases with higher age at first marriage and first birth, it appears to decrease with advancing age of women. This pattern needs further explanation from the authors to clarify the underlying reasons.

Reply: Thank you for pointing this out. We agree that this is an important pattern that requires clarification. We have now added a brief explanation in the revised results section. While women who marry or give birth at later ages tend to have better reproductive health, likely due to greater physical readiness and increased care-seeking, RHI tends to decline among older women. This could reflect the cumulative effects of reproductive strain, repeated childbearing, or reduced access to health services over time.

Attachment

Submitted filename: Response_to_Reviewers_auresp_2.docx

pone.0329375.s005.docx (18.3KB, docx)

Decision Letter 2

Pijush Kanti Khan

16 Jul 2025

Does Low Fertility Indicate Better Reproductive Health Status? Evidence from Nationally Representative Survey in India

PONE-D-25-01359R2

Dear Dr. Sikdar,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements.

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Pijush Kanti Khan

PONE-D-25-01359R2

PLOS ONE

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Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 Table. Sensitivity analysis using Poisson regression models based on alternate Reproductive Health Index (RHI) specifications.

    (DOCX)

    pone.0329375.s001.docx (13.9KB, docx)
    Attachment

    Submitted filename: Comments.docx

    pone.0329375.s002.docx (16.4KB, docx)
    Attachment

    Submitted filename: plosone_review.docx

    pone.0329375.s003.docx (17.1KB, docx)
    Attachment

    Submitted filename: Response to Reviewers.docx

    pone.0329375.s004.docx (24.3KB, docx)
    Attachment

    Submitted filename: Response_to_Reviewers_auresp_2.docx

    pone.0329375.s005.docx (18.3KB, docx)

    Data Availability Statement

    The dataset used in this study are publicly available and can be accessed from DHS Program: https://dhsprogram.com/. Any researcher can access this dataset from DHS after registering at: https://dhsprogram.com/data/new-user-registration.cfm and get permission to access the data at: https://dhsprogram.com/data/dataset/India_Standard-DHS_2020.cfm?flag=1.


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