Skip to main content
Annals of Surgery logoLink to Annals of Surgery
. 1996 Oct;224(4):453–462. doi: 10.1097/00000658-199610000-00004

"Keyhole" coronary artery bypass surgery.

R J Landreneau 1, M J Mack 1, J A Magovern 1, T A Acuff 1, D H Benckart 1, T A Sakert 1, L S Fetterman 1, B P Griffith 1
PMCID: PMC1235404  PMID: 8857850

Abstract

OBJECTIVE: The objective of this study was to identify the utility of "keyhole" thoracotomy approaches to single vessel coronary artery bypass surgery. SUMMARY BACKGROUND DATA: Although minimally invasive surgery is efficacious in a wide variety of surgical disciplines, it has been slow to emerge in cardiac surgery. Among 49 selected patients, the authors have used a left anterior keyhole thoracotomy (6 cm in length) combined with complete dissection of the eternal mammary artery (IMA) pedicle under thoracoscopic guidance or directly through the keyhole incision to accomplish IMA coronary artery bypass grafting (CABG) to the left anterior descending (LAD) coronary artery circulation or to the right coronary artery (RCA). METHODS: Keyhole CABG was accomplished in 46 of 49 patients in which this approach was attempted. All patients had significant (> 70%) obstruction of a dominant coronary artery that had failed or that was inappropriate for endovascular catheter treatment (percutaneous transluminal coronary angioplasty or stenting). Forty-four of the 49 patients had proximal LAD and 5 had proximal RCA stenoses. The mean age of the patients (35 men and 14 women) was 61 years, and their median New York Heart Association anginal class was III. The mean left ventricular ejection fraction was 42%. Femoral cardiopulmonary bypass support was used in 9 (19%) of 46 patients successfully managed with the keyhole procedure. Short-acting beta-blockade was used in the majority of patients (38 of 46) to reduce heart rate and the vigor of cardiac contraction. RESULTS: As 49 patients have survived operation, which averaged 248 minutes in duration. Median, postoperative endotracheal intubation time for keyhole patients was 6 hours with 25 of 46 patients being extubated before leaving the operating room. The median hospital stay was 4.3 days. Conversion to sternotomy was required in three patients to accomplish bypass because of inadequate internal mammary conduits or acute cardiovascular decompensation during an attempted off-bypass keyhole procedure Postoperative complications were limited to respiratory difficulty in three patients and the development of a deep wound infection in one patient. Nine (19%) of 46 patients received postoperative transfusion. There have been no intraoperative or postoperative infarctions, and angina has been controlled in all but one patient who subsequently had an IMA-RCA anastomotic stenosis managed successfully with percutaneous transluminal coronary angioplasty. CONCLUSIONS: These early results with keyhole CABG are encouraging. As experience broadens, keyhole CABG may become a reasonable alternative to repeated endovascular interventions or sternotomy approaches to recalcitrant single-vessel coronary arterial disease involving the proximal LAD or RCA.

Full text

PDF
453

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Acuff T. E., Landreneau R. J., Griffith B. P., Mack M. J. Minimally invasive coronary artery bypass grafting. Ann Thorac Surg. 1996 Jan;61(1):135–137. doi: 10.1016/0003-4975(95)00907-8. [DOI] [PubMed] [Google Scholar]
  2. Ankeny J. L. Editorial: To use or not to use the pump oxygenator in coronary bypass operations. Ann Thorac Surg. 1975 Jan;19(1):108–109. doi: 10.1016/s0003-4975(10)65744-x. [DOI] [PubMed] [Google Scholar]
  3. Benetti F. J. Coronary artery bypass without extracorporeal circulation versus percutaneous transluminal coronary angioplasty: comparison of costs. J Thorac Cardiovasc Surg. 1991 Nov;102(5):802–803. [PubMed] [Google Scholar]
  4. Benetti F. J., Naselli G., Wood M., Geffner L. Direct myocardial revascularization without extracorporeal circulation. Experience in 700 patients. Chest. 1991 Aug;100(2):312–316. doi: 10.1378/chest.100.2.312. [DOI] [PubMed] [Google Scholar]
  5. Cameron A. A., Green G. E., Brogno D. A., Thornton J. Internal thoracic artery grafts: 20-year clinical follow-up. J Am Coll Cardiol. 1995 Jan;25(1):188–192. doi: 10.1016/0735-1097(94)00332-k. [DOI] [PubMed] [Google Scholar]
  6. Favaloro R. G. Saphenous vein autograft replacement of severe segmental coronary artery occlusion: operative technique. Ann Thorac Surg. 1968 Apr;5(4):334–339. doi: 10.1016/s0003-4975(10)66351-5. [DOI] [PubMed] [Google Scholar]
  7. Garrett H. E., Dennis E. W., DeBakey M. E. Aortocoronary bypass with saphenous vein graft. Seven-year follow-up. JAMA. 1973 Feb 12;223(7):792–794. [PubMed] [Google Scholar]
  8. Hamm C. W., Reimers J., Ischinger T., Rupprecht H. J., Berger J., Bleifeld W. A randomized study of coronary angioplasty compared with bypass surgery in patients with symptomatic multivessel coronary disease. German Angioplasty Bypass Surgery Investigation (GABI) N Engl J Med. 1994 Oct 20;331(16):1037–1043. doi: 10.1056/NEJM199410203311601. [DOI] [PubMed] [Google Scholar]
  9. King S. B., 3rd, Lembo N. J., Weintraub W. S., Kosinski A. S., Barnhart H. X., Kutner M. H., Alazraki N. P., Guyton R. A., Zhao X. Q. A randomized trial comparing coronary angioplasty with coronary bypass surgery. Emory Angioplasty versus Surgery Trial (EAST) N Engl J Med. 1994 Oct 20;331(16):1044–1050. doi: 10.1056/NEJM199410203311602. [DOI] [PubMed] [Google Scholar]
  10. Kolessov V. I. Mammary artery-coronary artery anastomosis as method of treatment for angina pectoris. J Thorac Cardiovasc Surg. 1967 Oct;54(4):535–544. [PubMed] [Google Scholar]
  11. Labovitz A. J., Barth C., Castello R., Ojile M., Kern M. J. Attenuation of myocardial ischemia during coronary occlusion by ultrashort-acting beta adrenergic blockade. Am Heart J. 1991 May;121(5):1347–1352. doi: 10.1016/0002-8703(91)90137-7. [DOI] [PubMed] [Google Scholar]
  12. Landau C., Lange R. A., Hillis L. D. Percutaneous transluminal coronary angioplasty. N Engl J Med. 1994 Apr 7;330(14):981–993. doi: 10.1056/NEJM199404073301407. [DOI] [PubMed] [Google Scholar]
  13. Landreneau R. J., Mack M. J., Hazelrigg S. R., Dowling R. D., Acuff T. E., Magee M. J., Ferson P. F. Video-assisted thoracic surgery: basic technical concepts and intercostal approach strategies. Ann Thorac Surg. 1992 Oct;54(4):800–807. doi: 10.1016/0003-4975(92)91040-g. [DOI] [PubMed] [Google Scholar]
  14. Landreneau R. J., Mack M. J., Keenan R. J., Hazelrigg S. R., Dowling R. D., Ferson P. F. Strategic planning for video-assisted thoracic surgery. Ann Thorac Surg. 1993 Sep;56(3):615–619. doi: 10.1016/0003-4975(93)90930-g. [DOI] [PubMed] [Google Scholar]
  15. Loop F. D., Lytle B. W., Cosgrove D. M., Stewart R. W., Goormastic M., Williams G. W., Golding L. A., Gill C. C., Taylor P. C., Sheldon W. C. Influence of the internal-mammary-artery graft on 10-year survival and other cardiac events. N Engl J Med. 1986 Jan 2;314(1):1–6. doi: 10.1056/NEJM198601023140101. [DOI] [PubMed] [Google Scholar]
  16. Moshkovitz Y., Lusky A., Mohr R. Coronary artery bypass without cardiopulmonary bypass: analysis of short-term and mid-term outcome in 220 patients. J Thorac Cardiovasc Surg. 1995 Oct;110(4 Pt 1):979–987. doi: 10.1016/s0022-5223(05)80165-5. [DOI] [PubMed] [Google Scholar]
  17. Murry C. E., Richard V. J., Reimer K. A., Jennings R. B. Ischemic preconditioning slows energy metabolism and delays ultrastructural damage during a sustained ischemic episode. Circ Res. 1990 Apr;66(4):913–931. doi: 10.1161/01.res.66.4.913. [DOI] [PubMed] [Google Scholar]
  18. Olearchyk A. S. Vasilii I. Kolesov. A pioneer of coronary revascularization by internal mammary-coronary artery grafting. J Thorac Cardiovasc Surg. 1988 Jul;96(1):13–18. [PubMed] [Google Scholar]
  19. Pfister A. J., Zaki M. S., Garcia J. M., Mispireta L. A., Corso P. J., Qazi A. G., Boyce S. W., Coughlin T. R., Jr, Gurny P. Coronary artery bypass without cardiopulmonary bypass. Ann Thorac Surg. 1992 Dec;54(6):1085–1092. doi: 10.1016/0003-4975(92)90074-e. [DOI] [PubMed] [Google Scholar]
  20. Robinson M. C., Gross D. R., Zeman W., Stedje-Larsen E. Minimally invasive coronary artery bypass grafting: a new method using an anterior mediastinotomy. J Card Surg. 1995 Sep;10(5):529–536. doi: 10.1111/j.1540-8191.1995.tb00628.x. [DOI] [PubMed] [Google Scholar]
  21. Sculpher M. J., Seed P., Henderson R. A., Buxton M. J., Pocock S. J., Parker J., Joy M. D., Sowton E., Hampton J. R. Health service costs of coronary angioplasty and coronary artery bypass surgery: the Randomised Intervention Treatment of Angina (RITA) trial. Lancet. 1994 Oct 1;344(8927):927–930. doi: 10.1016/s0140-6736(94)92274-8. [DOI] [PubMed] [Google Scholar]
  22. Stanbridge R. D., Symons G. V., Banwell P. E. Minimal-access surgery for coronary artery revascularisation. Lancet. 1995 Sep 23;346(8978):837–837. doi: 10.1016/s0140-6736(95)91650-4. [DOI] [PubMed] [Google Scholar]
  23. Ullyot D. J. Look ma, no hands! Ann Thorac Surg. 1996 Jan;61(1):10–11. doi: 10.1016/0003-4975(95)00891-8. [DOI] [PubMed] [Google Scholar]

Articles from Annals of Surgery are provided here courtesy of Lippincott, Williams, and Wilkins

RESOURCES