Skip to main content
Journal of Anatomy logoLink to Journal of Anatomy
. 1977 Sep;124(Pt 1):217–222.

Changes in the mucosal surface area of the small gut of rats of different ages.

L Pénzes, I Skála
PMCID: PMC1235525  PMID: 914702

Abstract

Changes in the mucosal surface area of the small intestine of the ageing male Wistar rat were investigated. The results show that the mucosal surface area (Ma) and, even more, the mucosal area per unit serosal area (Ra) diminishes along the length of the small intestine (excluding the duodenum) in the young rat. In adults, however, there is relative constancy of these parameters along the small intestine. The serosal circumference (Sc) of the intestinal segments investigated increased considerably with advancing age.

Full text

PDF
217

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Boyne R., Fell B. F., Robb I. The surface area of the intestinal mucosa in the lactating rat. J Physiol. 1966 Apr;183(3):570–575. doi: 10.1113/jphysiol.1966.sp007884. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Clarke R. M. The effect of growth and of fasting on the number of villi and crypts in the small intestine of the albino rat. J Anat. 1972 May;112(Pt 1):27–33. [PMC free article] [PubMed] [Google Scholar]
  3. FABRY P. [A simple method for standard laboratory diets with various contents of principal nutrients]. Cesk Fysiol. 1959 Nov;8:529–533. [PubMed] [Google Scholar]
  4. FELL B. F., SMITH K. A., CAMPBELL R. M. Hypertrophic and hyperplastic changes in the alimentary canal of the lactating rat. J Pathol Bacteriol. 1963 Jan;85:179–188. doi: 10.1002/path.1700850117. [DOI] [PubMed] [Google Scholar]
  5. FISHER R. B., PARSONS D. S. The gradient of mucosal surface area in the small intestine of the rat. J Anat. 1950 Jul;84(3):272–282. [PMC free article] [PubMed] [Google Scholar]
  6. FISHER R. B. The absorption of water and of some small solute molecules from the isolated small intestine of the rat. J Physiol. 1955 Dec 29;130(3):655–664. doi: 10.1113/jphysiol.1955.sp005433. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Forrester J. M. The number of villi in rat's jejunum and ileum: effect of normal growth, partial enterectomy, and tube feeding. J Anat. 1972 Feb;111(Pt 2):283–291. [PMC free article] [PubMed] [Google Scholar]
  8. Hromádková V., Skála I. Factors influencing the assessment of size of the mucosal surface and length of the small intestine in rats. Digestion. 1968;1(3):149–158. doi: 10.1159/000196847. [DOI] [PubMed] [Google Scholar]
  9. Levin R. J. Techniques, terminology and parameters in intestinal absorption. Br Med Bull. 1967 Sep;23(3):209–212. doi: 10.1093/oxfordjournals.bmb.a070557. [DOI] [PubMed] [Google Scholar]
  10. Permezel N. C., Webling D. D. The length and mucosal surface area of the small and large gut in young rats. J Anat. 1971 Feb;108(Pt 2):295–296. [PMC free article] [PubMed] [Google Scholar]
  11. Wood H. O. The surface area of the intestinal mucosa in the rat and in the cat. J Anat. 1944 Apr;78(Pt 3):103–105. [PMC free article] [PubMed] [Google Scholar]

Articles from Journal of Anatomy are provided here courtesy of Anatomical Society of Great Britain and Ireland

RESOURCES