Abstract
Trochlear nerves from two human fetuses, and digital nerves from a third, have been examined by electron microscopy. Very marked differences in maturation were found between trochlear nerves of fetuses of ages differing only by 2--3 weeks, and between proximal and distal parts of the same trochlear nerve. Immaturity was reflected in paucity of endoneurial space and collagen and in the rarity, or virtual absence, of endoneurial fibroblasts. Circumstantial evidence of collagen formation by Schwann cells has been presented and discussed.
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- Cravioto H. The role of Schwann cells in the development of human peripheral nerves. An electron microscopic study. J Ultrastruct Res. 1965 Jun;12(5):634–651. doi: 10.1016/s0022-5320(65)80053-3. [DOI] [PubMed] [Google Scholar]
- Eames R. A., Gamble H. J. Schwann cell relationships in normal human cutaneous nerves. J Anat. 1970 May;106(Pt 3):417–435. [PMC free article] [PubMed] [Google Scholar]
- GAMBLE H. J. COMPARATIVE ELECTRON-MICROSCOPIC OBSERVATIONS ON THE CONNECTIVE TISSUES OF A PERIPHERAL NERVE AND A SPINAL NERVE ROOT IN THE RAT. J Anat. 1964 Jan;98:17–26. [PMC free article] [PubMed] [Google Scholar]
- GAMBLE H. J., EAMES R. A. AN ELECTRON MICROSCOPE STUDY OF THE CONNECTIVE TISSUES OF HUMAN PERIPHERAL NERVE. J Anat. 1964 Oct;98:655–663. [PMC free article] [PubMed] [Google Scholar]
- NATHANIEL E. J., PEASE D. C. COLLAGEN AND BASEMENT MEMBRANE FORMATION BY SCHWANN CELLS DURING NERVE REGENERATION. J Ultrastruct Res. 1963 Dec;52:550–560. doi: 10.1016/s0022-5320(63)80084-2. [DOI] [PubMed] [Google Scholar]
- Ochoa J. The sural nerve of the human foetus: electron microscope observations and counts of axons. J Anat. 1971 Feb;108(Pt 2):231–245. [PMC free article] [PubMed] [Google Scholar]
- Ochoa J., Vial J. D. Behaviour of peripheral nerve structures in chronic neuropathies, with special reference to the Schwann cell. J Anat. 1967 Nov;102(Pt 1):95–111. [PMC free article] [PubMed] [Google Scholar]
- RICHARDSON K. C., JARETT L., FINKE E. H. Embedding in epoxy resins for ultrathin sectioning in electron microscopy. Stain Technol. 1960 Nov;35:313–323. doi: 10.3109/10520296009114754. [DOI] [PubMed] [Google Scholar]
- THOMAS P. K. THE DEPOSITION OF COLLAGEN IN RELATION TO SCHWANN CELL BASEMENT MEMBRANE DURING PERIPHERAL NERVE REGENERATION. J Cell Biol. 1964 Nov;23:375–382. doi: 10.1083/jcb.23.2.375. [DOI] [PMC free article] [PubMed] [Google Scholar]