Abstract
A technique for the determination of cardiac output in the cat by the thermal dilution method is described. The values of cardiac output assessed by thermal dilution and the values of left ventricular function assessed echocardiographically are compared. Values of cardiac output obtained by thermal dilution compare favourably with values obtained by other investigators by indicator dye dilution, the Fick method and electromagnetic flowmeter technique. The technique of thermal dilution in the cat was consistent and simple to perform. The calculation of ventricular volumes and cardiac output echocardiographically using formulae suggested in man was unsuccessful. Such formulae based on assumptions of cardiac shape and contractility do not appear valid in the cat. Statistical analysis demonstrated a positive correlation between the cardiac output determined by thermodilution and the left ventricular diastolic and systolic dimensions determined echocardiographically. A positive correlation was also shown between the cardiac output and the cardiac index, the left ventricular diastolic dimension and the left ventricular systolic dimension and the percent change in minor diameter and the velocity of circumferential fibre shortening. A negative correlation existed between the left ventricular systolic dimension and the velocity of circumferential fibre shortening and the ejection time and the velocity of circumferential fibre shortening.
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- Allen D. G. Echocardiographic study of the anesthetized cat. Can J Comp Med. 1982 Apr;46(2):115–122. [PMC free article] [PubMed] [Google Scholar]
- BARTORELLI C., GEROLA A. TIDAL VOLUME, OXYGEN UPTAKE, CARDIAC OUTPUT, AND BODY SURFACE IN THE CAT. Am J Physiol. 1963 Sep;205:588–590. doi: 10.1152/ajplegacy.1963.205.3.588. [DOI] [PubMed] [Google Scholar]
- BAXTER I. G., CUNNINGHAM D. J. C., PEARCE J. W. Comparison of cardiac output determinations in the cat by direct Fick and flowmeter methods. J Physiol. 1952 Nov;118(3):299–309. doi: 10.1113/jphysiol.1952.sp004795. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Forrest J. B., Todd M. H., Cragg D. J. A simple method of percutaneous cannulation of the pulmonary artery in small mammals. Can Anaesth Soc J. 1979 Jan;26(1):58–60. doi: 10.1007/BF03039456. [DOI] [PubMed] [Google Scholar]
- Fortun N. J., Hood W. P., Jr, Sherman M. E., Craige E. Determination of left ventricular volumes by ultrasound. Circulation. 1971 Oct;44(4):575–584. doi: 10.1161/01.cir.44.4.575. [DOI] [PubMed] [Google Scholar]
- Gutgesell H. P., Paquet M., Duff D. F., McNamara D. G. Evaluation of left ventricular size and function by echocardiography. Results in normal children. Circulation. 1977 Sep;56(3):457–462. doi: 10.1161/01.cir.56.3.457. [DOI] [PubMed] [Google Scholar]
- Hirota Y., Suwa M., Hori K., Takatsu T. Dynamic echoventriculography. Noninvasive assessment of effects of nitroglycerin, phenylephrine, isoproterenol, and propranolol on the human cardiovascular system. Jpn Heart J. 1978 Sep;19(5):719–731. doi: 10.1536/ihj.19.719. [DOI] [PubMed] [Google Scholar]
- Machii K., Tamura T., Natsume T., Umeda T. Echocardiographic left ventricular volume determination by direct measurements of the major and minor axes. Jpn Circ J. 1977 May;41(5):501–505. doi: 10.1253/jcj.41.501. [DOI] [PubMed] [Google Scholar]
- Martin M. A., Fieller N. R. Echocardiography in cardiovascular drug assessment. Br Heart J. 1979 May;41(5):536–543. doi: 10.1136/hrt.41.5.536. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Muir W. W., Skarda R. T., Milne D. W. Estimation of cardiac output in the horse by thermodilution techniques. Am J Vet Res. 1976 Jun;37(6):697–700. [PubMed] [Google Scholar]
- Murray J. A., Johnston W., Reid J. M. Echocardiographic determination of left ventricular dimensions, volumes and performance. Am J Cardiol. 1972 Aug;30(3):252–257. doi: 10.1016/0002-9149(72)90068-9. [DOI] [PubMed] [Google Scholar]
- Nadeau R. A., Colebatch H. J. Normal respiratory and circulatory values in the cat. J Appl Physiol. 1965 Sep;20(5):836–838. doi: 10.1152/jappl.1965.20.5.836. [DOI] [PubMed] [Google Scholar]
- Pipers F. S., Reef V., Hamlin R. L. Echocardiography in the domestic cat. Am J Vet Res. 1979 Jun;40(6):882–886. [PubMed] [Google Scholar]
- Pombo J. F., Troy B. L., Russell R. O., Jr Left ventricular volumes and ejection fraction by echocardiography. Circulation. 1971 Apr;43(4):480–490. doi: 10.1161/01.cir.43.4.480. [DOI] [PubMed] [Google Scholar]
- Popp R. L., Harrison D. C. Ultrasonic cardiac echography for determining stroke volume and valvular regurgitation. Circulation. 1970 Mar;41(3):493–502. doi: 10.1161/01.cir.41.3.493. [DOI] [PubMed] [Google Scholar]
- Quinones M. A., Gaasch W. H., Alexander J. K. Echocardiographic assessment of left ventricular function with special reference to normalized velocities. Circulation. 1974 Jul;50(1):42–51. doi: 10.1161/01.cir.50.1.42. [DOI] [PubMed] [Google Scholar]
- Quinones M. A., Gaasch W. H., Alexander J. K. Influence of acute changes in preload, afterload, contractile state and heart rate on ejection and isovolumic indices of myocardial contractility in man. Circulation. 1976 Feb;53(2):293–302. doi: 10.1161/01.cir.53.2.293. [DOI] [PubMed] [Google Scholar]
- Rasmussen S., Corya B. C., Phillips J. F., Black M. J. Unreliability of M-mode left ventricular dimensions for calculating stroke volume and cardiac output in patients without heart disease. Chest. 1982 May;81(5):614–619. doi: 10.1378/chest.81.5.614. [DOI] [PubMed] [Google Scholar]
- Sanmarco M. E., Philips C. M., Marquez L. A., Hall C., Davila J. C. Measurement of cardiac output by thermal dilution. Am J Cardiol. 1971 Jul;28(1):54–58. doi: 10.1016/0002-9149(71)90034-8. [DOI] [PubMed] [Google Scholar]
- Teichholz L. E., Kreulen T., Herman M. V., Gorlin R. Problems in echocardiographic volume determinations: echocardiographic-angiographic correlations in the presence of absence of asynergy. Am J Cardiol. 1976 Jan;37(1):7–11. doi: 10.1016/0002-9149(76)90491-4. [DOI] [PubMed] [Google Scholar]
- Vatner S. F., Braunwald E. Cardiovascular control mechanisms in the conscious state. N Engl J Med. 1975 Nov 6;293(19):970–976. doi: 10.1056/NEJM197511062931906. [DOI] [PubMed] [Google Scholar]
- Warren D. J., Ledingham J. G. Cardiac output in the conscious rabbit: an analysis of the thermodilution technique. J Appl Physiol. 1974 Feb;36(2):246–251. doi: 10.1152/jappl.1974.36.2.246. [DOI] [PubMed] [Google Scholar]