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Canadian Journal of Comparative Medicine logoLink to Canadian Journal of Comparative Medicine
. 1983 Apr;47(2):127–132.

Enterotoxemia in the goat: the humoral response and local tissue reaction following vaccination with two different bacterin-toxoids.

T E Blackwell, D G Butler, J A Bell
PMCID: PMC1235905  PMID: 6309346

Abstract

A vaccination trial involving 72 goats was designed to compare the epsilon antitoxin titres and local reactions at the injection sites, of two commercial enterotoxemia vaccines. Three dosage regimens were used for each vaccine (12 goats per group). Although no significant differences were noted in humoral immune response between the two vaccines (P = 0.05), one vaccine regime resulted in low titres (P = 0.05) on two occasions. Local tissue reactions at injection sites persisted for six months in 53% of the goats regardless of vaccine used or dosage administered. No immunological basis for the reported differences in vaccine efficacy between sheep and goats was observed in this trial.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Jansen B. C. The prevention of enterotoxaemia (pulpy kidney disease) by vaccination. Bull Off Int Epizoot. 1967 Nov-Dec;67(11):1539–1567. [PubMed] [Google Scholar]
  2. Jansen B. C. The production of a basic immunity against pulpy kidney disease. Onderstepoort J Vet Res. 1967 Apr;34(1):65–79. [PubMed] [Google Scholar]

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