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. 1976 Aug;125(2):100–109.

Diagnosis and Treatment of Amanita Phalloides-Type Mushroom Poisoning

Use of Thioctic Acid

Charles E Becker 1,2,3,4,5, Theodore G Tong 1,2,3,4,5, Robert L Roe 1,2,3,4,5, Robert A T Scott 1,2,3,4,5, Michael B MacQuarrie 1,2,3,4,5, Udo Boerner 1,2,3,4,5, Frederic Bartter 1,2,3,4,5
PMCID: PMC1237216  PMID: 788340

Abstract

The number of cases of mushroom poisoning is increasing as a result of the increasing popularity of “wild” mushroom consumption. Amanitin and phalloidin cytotoxins found in some Amanita and Galerina species produce the most severe and frequent life-threatening symptoms of Amanita phalloidestype poisoning. Delay in onset of symptoms, individual susceptibility variation and lack of rapid and reliable identification have contributed to the significant morbidity and mortality of this type of poisoning.

A rapid chromatographic assay for identifying the potent cytotoxins and apparently successful management using thioctic acid of two cases of A. phalloides-type mushroom poisoning are reported. All known cases of A. phalloides-type mushroom poisoning treated with thioctic acid in the United States are summarized.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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