Abstract
A serum Venereal Disease Research Laboratories (VDRL) test was carried out in 216 elderly patients with dementia or “functional” psychiatric illness, or both, as part of a community based screening program. The VDRL test was positive in 13 patients, 11 of whom (5.1 percent) had an actual past or present syphilitic infection as confirmed by the fluorescent treponemal antibody absorption test (FTA-Abs). In six patients (2.8 percent) syphilis was newly detected, and in another two patients previously detected syphilis had been inadequately treated. Only two (0.9 percent) biologic false positive reactors were detected. These results question the belief that aging per se is a common cause of the biologic false positive reaction; and indicate a relatively high incidence of past or present syphilitic infection in geriatric patients with psychiatric illness in the community who have been referred for crisis intervention.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- BELL R. E. The value of routine serologic tests for syphilis on hospital admission. Am J Clin Pathol. 1959 Dec;32:521–525. doi: 10.1093/ajcp/32.6.521. [DOI] [PubMed] [Google Scholar]
- Carr R. D., Becker S. W., Carpenter C. M. The biological false-positive phenomenon in elderly men. Arch Dermatol. 1966 Apr;93(4):393–395. [PubMed] [Google Scholar]
- FIUMARA N. J., WHITE H. Primary syphilis in an eighty-one-year-old man. N Engl J Med. 1960 Jan 7;262:31–31. doi: 10.1056/nejm196001072620108. [DOI] [PubMed] [Google Scholar]
- Markson E., Kwoh A., Cumming J., Cumming E. Alternatives to hospitalization for psychiatrically ill geriatric patients. Am J Psychiatry. 1971 Feb;127(8):1055–1062. doi: 10.1176/ajp.127.8.1055. [DOI] [PubMed] [Google Scholar]
- Steel K., Williams T. F., Fairbank M., Knox K. Laboratory screening in the evaluation and placement of geriatric patients. J Am Geriatr Soc. 1974 Dec;22(12):538–543. doi: 10.1111/j.1532-5415.1974.tb04825.x. [DOI] [PubMed] [Google Scholar]
- Tuffanelli D. L. Ageing and false positive reactions for syphilis. Br J Vener Dis. 1966 Mar;42(1):40–41. doi: 10.1136/sti.42.1.40. [DOI] [PMC free article] [PubMed] [Google Scholar]
- YOUNG A. W., Jr, SUN P. A. EARLY SYPHILIS AND THE PROBLEM OF POSITIVE SEROLOGIC FINDINGS IN THE GERIATRIC PATIENT. J Am Geriatr Soc. 1965 May;13:462–468. doi: 10.1111/j.1532-5415.1965.tb00085.x. [DOI] [PubMed] [Google Scholar]
