Skip to main content
NCBI home page
Environmental Health Perspectives logoLink to Environmental Health Perspectives
. 2000 Dec;108(12):A543–A544. doi: 10.1289/ehp.108-a543

TCE Meta-Analyses: Wartenberg et al.'s Response.

D Wartenberg 1, D Reyner 1
PMCID: PMC1240211  PMID: 11133407

Abstract

Comments on Trichloroethylene and Cancer: Epidemiologic Evidence by Daniel Wartenberg, Daniel Reyner, and Cheryl Siegel Scott. Environ Health Perspect 108(suppl 2):161-176 (2000).

Full Text

The Full Text of this article is available as a PDF (95.9 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Amdur M. O., Bayles J., Ugro V., Underhill D. W. Comparative irritant potency of sulfate salts. Environ Res. 1978 Jul;16(1-3):1–8. doi: 10.1016/0013-9351(78)90135-4. [DOI] [PubMed] [Google Scholar]
  2. Anttila A., Pukkala E., Sallmén M., Hernberg S., Hemminki K. Cancer incidence among Finnish workers exposed to halogenated hydrocarbons. J Occup Environ Med. 1995 Jul;37(7):797–806. doi: 10.1097/00043764-199507000-00008. [DOI] [PubMed] [Google Scholar]
  3. Anttila A., Pukkala E., Sallmén M., Hernberg S., Hemminki K. Cancer incidence among Finnish workers exposed to halogenated hydrocarbons. J Occup Environ Med. 1995 Jul;37(7):797–806. doi: 10.1097/00043764-199507000-00008. [DOI] [PubMed] [Google Scholar]
  4. Arenholt-Bindslev D., Breinholt V., Preiss A., Schmalz G. Time-related bisphenol-A content and estrogenic activity in saliva samples collected in relation to placement of fissure sealants. Clin Oral Investig. 1999 Sep;3(3):120–125. doi: 10.1007/s007840050089. [DOI] [PubMed] [Google Scholar]
  5. Axelson O., Seldén A., Andersson K., Hogstedt C. Updated and expanded Swedish cohort study on trichloroethylene and cancer risk. J Occup Med. 1994 May;36(5):556–562. [PubMed] [Google Scholar]
  6. Axelson O., Seldén A., Andersson K., Hogstedt C. Updated and expanded Swedish cohort study on trichloroethylene and cancer risk. J Occup Med. 1994 May;36(5):556–562. [PubMed] [Google Scholar]
  7. Birner G., Vamvakas S., Dekant W., Henschler D. Nephrotoxic and genotoxic N-acetyl-S-dichlorovinyl-L-cysteine is a urinary metabolite after occupational 1,1,2-trichloroethene exposure in humans: implications for the risk of trichloroethene exposure. Environ Health Perspect. 1993 Mar;99:281–284. doi: 10.1289/ehp.9399281. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Blair A., Hartge P., Stewart P. A., McAdams M., Lubin J. Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: extended follow up. Occup Environ Med. 1998 Mar;55(3):161–171. doi: 10.1136/oem.55.3.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Blair A., Hartge P., Stewart P. A., McAdams M., Lubin J. Mortality and cancer incidence of aircraft maintenance workers exposed to trichloroethylene and other organic solvents and chemicals: extended follow up. Occup Environ Med. 1998 Mar;55(3):161–171. doi: 10.1136/oem.55.3.161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  10. Boice J. D., Jr, Marano D. E., Fryzek J. P., Sadler C. J., McLaughlin J. K. Mortality among aircraft manufacturing workers. Occup Environ Med. 1999 Sep;56(9):581–597. doi: 10.1136/oem.56.9.581. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Brüning T., Bolt H. M. Renal toxicity and carcinogenicity of trichloroethylene: key results, mechanisms, and controversies. Crit Rev Toxicol. 2000 May;30(3):253–285. doi: 10.1080/10408440091159202. [DOI] [PubMed] [Google Scholar]
  12. Brüning T., Sundberg A. G., Birner G., Lammert M., Bolt H. M., Appelkvist E. L., Nilsson R., Dallner G. Glutathione transferase alpha as a marker for tubular damage after trichloroethylene exposure. Arch Toxicol. 1999 Jun-Jul;73(4-5):246–254. doi: 10.1007/s002040050613. [DOI] [PubMed] [Google Scholar]
  13. Colditz G. A., Burdick E., Mosteller F. Heterogeneity in meta-analysis of data from epidemiologic studies: a commentary. Am J Epidemiol. 1995 Aug 15;142(4):371–382. doi: 10.1093/oxfordjournals.aje.a117644. [DOI] [PubMed] [Google Scholar]
  14. DerSimonian R., Laird N. Meta-analysis in clinical trials. Control Clin Trials. 1986 Sep;7(3):177–188. doi: 10.1016/0197-2456(86)90046-2. [DOI] [PubMed] [Google Scholar]
  15. Dosemeci M., Cocco P., Chow W. H. Gender differences in risk of renal cell carcinoma and occupational exposures to chlorinated aliphatic hydrocarbons. Am J Ind Med. 1999 Jul;36(1):54–59. doi: 10.1002/(sici)1097-0274(199907)36:1<54::aid-ajim8>3.0.co;2-0. [DOI] [PubMed] [Google Scholar]
  16. Fleiss J. L., Gross A. J. Meta-analysis in epidemiology, with special reference to studies of the association between exposure to environmental tobacco smoke and lung cancer: a critique. J Clin Epidemiol. 1991;44(2):127–139. doi: 10.1016/0895-4356(91)90261-7. [DOI] [PubMed] [Google Scholar]
  17. Fleming L. E., Ducatman A. M., Shalat S. L. Disease clusters in occupational medicine: a protocol for their investigation in the workplace. Am J Ind Med. 1992;22(1):33–47. doi: 10.1002/ajim.4700220104. [DOI] [PubMed] [Google Scholar]
  18. Fleming L. E., Ducatman A. M., Shalat S. L. Disease clusters: a central and ongoing role in occupational health. J Occup Med. 1991 Jul;33(7):818–825. [PubMed] [Google Scholar]
  19. Fung E. Y., Ewoldsen N. O., St Germain H. A., Jr, Marx D. B., Miaw C. L., Siew C., Chou H. N., Gruninger S. E., Meyer D. M. Pharmacokinetics of bisphenol A released from a dental sealant. J Am Dent Assoc. 2000 Jan;131(1):51–58. doi: 10.14219/jada.archive.2000.0019. [DOI] [PubMed] [Google Scholar]
  20. GILES D., HEWITT D., STEWART A., WEBB J. Malignant disease in childhood and diagnostic irradiation in utero. Lancet. 1956 Sep 1;271(6940):447–447. doi: 10.1016/s0140-6736(56)91923-7. [DOI] [PubMed] [Google Scholar]
  21. Goeptar A. R., Commandeur J. N., van Ommen B., van Bladeren P. J., Vermeulen N. P. Metabolism and kinetics of trichloroethylene in relation to toxicity and carcinogenicity. Relevance of the mercapturic acid pathway. Chem Res Toxicol. 1995 Jan-Feb;8(1):3–21. doi: 10.1021/tx00043a001. [DOI] [PubMed] [Google Scholar]
  22. González-Casado A., Navas N., del Olmo M., Vílchez J. L. Determination of bisphenol A in water by micro liquid-liquid extraction followed by silylation and gas chromatography-mass spectrometry analysis. J Chromatogr Sci. 1998 Nov;36(11):565–569. doi: 10.1093/chromsci/36.11.565. [DOI] [PubMed] [Google Scholar]
  23. Hardy R. J., Thompson S. G. Detecting and describing heterogeneity in meta-analysis. Stat Med. 1998 Apr 30;17(8):841–856. doi: 10.1002/(sici)1097-0258(19980430)17:8<841::aid-sim781>3.0.co;2-d. [DOI] [PubMed] [Google Scholar]
  24. Hatch M. C., Beyea J., Nieves J. W., Susser M. Cancer near the Three Mile Island nuclear plant: radiation emissions. Am J Epidemiol. 1990 Sep;132(3):397–417. doi: 10.1093/oxfordjournals.aje.a115673. [DOI] [PubMed] [Google Scholar]
  25. Hatch M. C., Beyea J., Nieves J. W., Susser M. Cancer near the Three Mile Island nuclear plant: radiation emissions. Am J Epidemiol. 1990 Sep;132(3):397–417. doi: 10.1093/oxfordjournals.aje.a115673. [DOI] [PubMed] [Google Scholar]
  26. Hatch M. C., Wallenstein S., Beyea J., Nieves J. W., Susser M. Cancer rates after the Three Mile Island nuclear accident and proximity of residence to the plant. Am J Public Health. 1991 Jun;81(6):719–724. doi: 10.2105/ajph.81.6.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Hatch M. C., Wallenstein S., Beyea J., Nieves J. W., Susser M. Cancer rates after the Three Mile Island nuclear accident and proximity of residence to the plant. Am J Public Health. 1991 Jun;81(6):719–724. doi: 10.2105/ajph.81.6.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  28. Henschler D., Vamvakas S., Lammert M., Dekant W., Kraus B., Thomas B., Ulm K. Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene. Arch Toxicol. 1995;69(5):291–299. doi: 10.1007/s002040050173. [DOI] [PubMed] [Google Scholar]
  29. Henschler D., Vamvakas S., Lammert M., Dekant W., Kraus B., Thomas B., Ulm K. Increased incidence of renal cell tumors in a cohort of cardboard workers exposed to trichloroethene. Arch Toxicol. 1995;69(5):291–299. doi: 10.1007/s002040050173. [DOI] [PubMed] [Google Scholar]
  30. Imai Y. Comments on "Estrogenicity of resin-based composites and sealants used in dentistry". Environ Health Perspect. 1999 Jun;107(6):A290–A292. doi: 10.1289/ehp.107-1566557. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Imai Y., Komabayashi T. Elution of bisphenol A from composite resin: a model experiment. Dent Mater J. 2000 Jun;19(2):133–138. doi: 10.4012/dmj.19.133. [DOI] [PubMed] [Google Scholar]
  32. Imai Y., Watanabe M., Ohsaki A. Analysis of major components and bisphenol A in commercial Bis-GMA and Bis-GMA-based resins using high performance liquid chromatography. Dent Mater J. 2000 Sep;19(3):263–269. doi: 10.4012/dmj.19.263. [DOI] [PubMed] [Google Scholar]
  33. Kato H., Schull W. J. Studies of the mortality of A-bomb survivors. 7. Mortality, 1950-1978: Part I. Cancer mortality. Radiat Res. 1982 May;90(2):395–432. [PubMed] [Google Scholar]
  34. Lash L. H., Parker J. C., Scott C. S. Modes of action of trichloroethylene for kidney tumorigenesis. Environ Health Perspect. 2000 May;108 (Suppl 2):225–240. doi: 10.1289/ehp.00108s2225. [DOI] [PMC free article] [PubMed] [Google Scholar]
  35. Lau J., Ioannidis J. P., Schmid C. H. Quantitative synthesis in systematic reviews. Ann Intern Med. 1997 Nov 1;127(9):820–826. doi: 10.7326/0003-4819-127-9-199711010-00008. [DOI] [PubMed] [Google Scholar]
  36. Lewis J. B., Rueggeberg F. A., Lapp C. A., Ergle J. W., Schuster G. S. Identification and characterization of estrogen-like components in commercial resin-based dental restorative materials. Clin Oral Investig. 1999 Sep;3(3):107–113. doi: 10.1007/s007840050087. [DOI] [PubMed] [Google Scholar]
  37. Mage D. T. Coarse particles and dust storm mortality. Environ Health Perspect. 2000 Jan;108(1):A12–A12. doi: 10.1289/ehp.108-a12a. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Mage D., Wilson W., Hasselblad V., Grant L. Assessment of human exposure to ambient particulate matter. J Air Waste Manag Assoc. 1999 Nov;49(11):1280–1291. doi: 10.1080/10473289.1999.10463964. [DOI] [PubMed] [Google Scholar]
  39. Manabe A., Kaneko S., Numazawa S., Itoh K., Inoue M., Hisamitsu H., Sasa R., Yoshida T. Detection of bisphenol-A in dental materials by gas chromatography-mass spectrometry. Dent Mater J. 2000 Mar;19(1):75–86. doi: 10.4012/dmj.19.75. [DOI] [PubMed] [Google Scholar]
  40. Mangano J. J. Low-level radiation harmed humans near Three Mile Island. Environ Health Perspect. 1997 Aug;105(8):786–787. doi: 10.1289/ehp.97105786. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. McLaughlin J. K., Blot W. J. A critical review of epidemiology studies of trichloroethylene and perchloroethylene and risk of renal-cell cancer. Int Arch Occup Environ Health. 1997;70(4):222–231. doi: 10.1007/s004200050211. [DOI] [PubMed] [Google Scholar]
  42. Moore M. M., Harrington-Brock K. Mutagenicity of trichloroethylene and its metabolites: implications for the risk assessment of trichloroethylene. Environ Health Perspect. 2000 May;108 (Suppl 2):215–223. doi: 10.1289/ehp.00108s2215. [DOI] [PMC free article] [PubMed] [Google Scholar]
  43. Morgan R. W., Kelsh M. A., Zhao K., Heringer S. Mortality of aerospace workers exposed to trichloroethylene. Epidemiology. 1998 Jul;9(4):424–431. [PubMed] [Google Scholar]
  44. Noda M., Komatsu H., Sano H. HPLC analysis of dental resin composites components. J Biomed Mater Res. 1999 Dec 5;47(3):374–378. doi: 10.1002/(sici)1097-4636(19991205)47:3<374::aid-jbm12>3.0.co;2-7. [DOI] [PubMed] [Google Scholar]
  45. Ohsaki A., Imai Y. Analysis of major components contained in Bis-GMA monomer. Dent Mater J. 1999 Dec;18(4):425–429. doi: 10.4012/dmj.18.425. [DOI] [PubMed] [Google Scholar]
  46. Olea N., Pulgar R., Pérez P., Olea-Serrano F., Rivas A., Novillo-Fertrell A., Pedraza V., Soto A. M., Sonnenschein C. Estrogenicity of resin-based composites and sealants used in dentistry. Environ Health Perspect. 1996 Mar;104(3):298–305. doi: 10.1289/ehp.96104298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  47. Olea N., Pulgar R., Pérez P., Olea-Serrano F., Rivas A., Novillo-Fertrell A., Pedraza V., Soto A. M., Sonnenschein C. Estrogenicity of resin-based composites and sealants used in dentistry. Environ Health Perspect. 1996 Mar;104(3):298–305. doi: 10.1289/ehp.96104298. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Poole C., Greenland S. Random-effects meta-analyses are not always conservative. Am J Epidemiol. 1999 Sep 1;150(5):469–475. doi: 10.1093/oxfordjournals.aje.a010035. [DOI] [PubMed] [Google Scholar]
  51. Poskrobko J., Dejnega M., Kiedik M. High-performance liquid chromatography with multi-wavelength detection of the bisphenol A impurities. J Chromatogr A. 2000 Jun 23;883(1-2):291–297. doi: 10.1016/s0021-9673(00)00418-0. [DOI] [PubMed] [Google Scholar]
  52. Pulgar R., Olea-Serrano M. F., Novillo-Fertrell A., Rivas A., Pazos P., Pedraza V., Navajas J. M., Olea N. Determination of bisphenol A and related aromatic compounds released from bis-GMA-based composites and sealants by high performance liquid chromatography. Environ Health Perspect. 2000 Jan;108(1):21–27. doi: 10.1289/ehp.0010821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Pulgar R., Olea-Serrano M. F., Novillo-Fertrell A., Rivas A., Pazos P., Pedraza V., Navajas J. M., Olea N. Determination of bisphenol A and related aromatic compounds released from bis-GMA-based composites and sealants by high performance liquid chromatography. Environ Health Perspect. 2000 Jan;108(1):21–27. doi: 10.1289/ehp.0010821. [DOI] [PMC free article] [PubMed] [Google Scholar]
  54. Ritz B. Cancer mortality among workers exposed to chemicals during uranium processing. J Occup Environ Med. 1999 Jul;41(7):556–566. doi: 10.1097/00043764-199907000-00004. [DOI] [PubMed] [Google Scholar]
  55. Rothman K. J. A sobering start for the cluster busters' conference. Am J Epidemiol. 1990 Jul;132(1 Suppl):S6–13. doi: 10.1093/oxfordjournals.aje.a115790. [DOI] [PubMed] [Google Scholar]
  56. Rothman K. J. A sobering start for the cluster busters' conference. Am J Epidemiol. 1990 Jul;132(1 Suppl):S6–13. doi: 10.1093/oxfordjournals.aje.a115790. [DOI] [PubMed] [Google Scholar]
  57. Stewart A. The role of epidemiology in the detection of harmful effects of radiation. Environ Health Perspect. 2000 Feb;108(2):93–96. doi: 10.1289/ehp.0010893. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Susser M. Consequences of the 1979 Three Mile Island accident continued: further comment. Environ Health Perspect. 1997 Jun;105(6):566–570. doi: 10.1289/ehp.105-1470087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Talbott E. O., Youk A. O., McHugh K. P., Shire J. D., Zhang A., Murphy B. P., Engberg R. A. Mortality among the residents of the Three Mile Island accident area: 1979-1992. Environ Health Perspect. 2000 Jun;108(6):545–552. doi: 10.1289/ehp.00108545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  60. Talbott E. O., Youk A. O., McHugh K. P., Shire J. D., Zhang A., Murphy B. P., Engberg R. A. Mortality among the residents of the Three Mile Island accident area: 1979-1992. Environ Health Perspect. 2000 Jun;108(6):545–552. doi: 10.1289/ehp.00108545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  61. Thompson S. G., Sharp S. J. Explaining heterogeneity in meta-analysis: a comparison of methods. Stat Med. 1999 Oct 30;18(20):2693–2708. doi: 10.1002/(sici)1097-0258(19991030)18:20<2693::aid-sim235>3.0.co;2-v. [DOI] [PubMed] [Google Scholar]
  62. Vamvakas S., Brüning T., Thomasson B., Lammert M., Baumüller A., Bolt H. M., Dekant W., Birner G., Henschler D., Ulm K. Renal cell cancer correlated with occupational exposure to trichloroethene. J Cancer Res Clin Oncol. 1998;124(7):374–382. doi: 10.1007/s004320050186. [DOI] [PubMed] [Google Scholar]
  63. Wartenberg D., Reyner D., Scott C. S. Trichloroethylene and cancer: epidemiologic evidence. Environ Health Perspect. 2000 May;108 (Suppl 2):161–176. doi: 10.1289/ehp.00108s2161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  64. Wartenberg D., Reyner D., Scott C. S. Trichloroethylene and cancer: epidemiologic evidence. Environ Health Perspect. 2000 May;108 (Suppl 2):161–176. doi: 10.1289/ehp.00108s2161. [DOI] [PMC free article] [PubMed] [Google Scholar]
  65. Weiss N. S. Cancer in relation to occupational exposure to trichloroethylene. Occup Environ Med. 1996 Jan;53(1):1–5. doi: 10.1136/oem.53.1.1. [DOI] [PMC free article] [PubMed] [Google Scholar]
  66. Wilson W. E., Suh H. H. Fine particles and coarse particles: concentration relationships relevant to epidemiologic studies. J Air Waste Manag Assoc. 1997 Dec;47(12):1238–1249. doi: 10.1080/10473289.1997.10464074. [DOI] [PubMed] [Google Scholar]
  67. Wing S., Richardson D., Armstrong D., Crawford-Brown D. A reevaluation of cancer incidence near the Three Mile Island nuclear plant: the collision of evidence and assumptions. Environ Health Perspect. 1997 Jan;105(1):52–57. doi: 10.1289/ehp.9710552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  68. Wing S., Richardson D., Armstrong D., Crawford-Brown D. A reevaluation of cancer incidence near the Three Mile Island nuclear plant: the collision of evidence and assumptions. Environ Health Perspect. 1997 Jan;105(1):52–57. doi: 10.1289/ehp.9710552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  69. Zeger S. L., Thomas D., Dominici F., Samet J. M., Schwartz J., Dockery D., Cohen A. Exposure measurement error in time-series studies of air pollution: concepts and consequences. Environ Health Perspect. 2000 May;108(5):419–426. doi: 10.1289/ehp.00108419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  70. del Olmo M., Zafra A., Jurado A. B., Vilchez J. L. Determination of bisphenol A (BPA) in the presence of phenol by first-derivative fluorescence following micro liquid-liquid extraction (MLLE). Talanta. 2000 Jan 10;50(6):1141–1148. doi: 10.1016/s0039-9140(99)00176-9. [DOI] [PubMed] [Google Scholar]

Articles from Environmental Health Perspectives are provided here courtesy of National Institute of Environmental Health Sciences

RESOURCES