Skip to main content
Environmental Health Perspectives logoLink to Environmental Health Perspectives
. 2001 Aug;109(8):A356–A357. doi: 10.1289/ehp.109-a356

To BaP or not to BaP? That is the question.

L S Goldstein
PMCID: PMC1240418  PMID: 11564626

Full Text

The Full Text of this article is available as a PDF (29.1 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Brune H., Deutsch-Wenzel R. P., Habs M., Ivankovic S., Schmähl D. Investigation of the tumorigenic response to benzo(a)pyrene in aqueous caffeine solution applied orally to Sprague-Dawley rats. J Cancer Res Clin Oncol. 1981;102(2):153–157. doi: 10.1007/BF00410666. [DOI] [PubMed] [Google Scholar]
  2. Chaloupka K., Steinberg M., Santostefano M., Rodriguez L. V., Goldstein L., Safe S. Induction of Cyp1a-1 and Cyp1a-2 gene expression by a reconstituted mixture of polynuclear aromatic hydrocarbons in B6C3F1 mice. Chem Biol Interact. 1995 Jun 14;96(3):207–221. doi: 10.1016/0009-2797(94)03586-w. [DOI] [PubMed] [Google Scholar]
  3. Culp S. J., Gaylor D. W., Sheldon W. G., Goldstein L. S., Beland F. A. A comparison of the tumors induced by coal tar and benzo[a]pyrene in a 2-year bioassay. Carcinogenesis. 1998 Jan;19(1):117–124. doi: 10.1093/carcin/19.1.117. [DOI] [PubMed] [Google Scholar]
  4. Culp S. J., Warbritton A. R., Smith B. A., Li E. E., Beland F. A. DNA adduct measurements, cell proliferation and tumor mutation induction in relation to tumor formation in B6C3F1 mice fed coal tar or benzo[a]pyrene. Carcinogenesis. 2000 Jul;21(7):1433–1440. [PubMed] [Google Scholar]
  5. Einolf H. J., Story W. T., Marcus C. B., Larsen M. C., Jefcoate C. R., Greenlee W. F., Yagi H., Jerina D. M., Amin S., Park S. S. Role of cytochrome P450 enzyme induction in the metabolic activation of benzo[c]phenanthrene in human cell lines and mouse epidermis. Chem Res Toxicol. 1997 May;10(5):609–617. doi: 10.1021/tx960174n. [DOI] [PubMed] [Google Scholar]
  6. Gaylor D. W., Culp S. J., Goldstein L. S., Beland F. A. Cancer risk estimation for mixtures of coal tars and benzo(a)pyrene. Risk Anal. 2000 Feb;20(1):81–85. doi: 10.1111/0272-4332.00008. [DOI] [PubMed] [Google Scholar]
  7. Gaylor D. W., Moolgavkar S., Krewski D., Goldstein L. S. Recent bioassay results on coal tars and benzo(a)pyrene: implications for risk assessment. Regul Toxicol Pharmacol. 1998 Oct;28(2):178–179. doi: 10.1006/rtph.1998.1237. [DOI] [PubMed] [Google Scholar]
  8. Goldstein L. S., Weyand E. H., Safe S., Steinberg M., Culp S. J., Gaylor D. W., Beland F. A., Rodriguez L. V. Tumors and DNA adducts in mice exposed to benzo[a]pyrene and coal tars: implications for risk assessment. Environ Health Perspect. 1998 Dec;106 (Suppl 6):1325–1330. doi: 10.1289/ehp.98106s61325. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Koganti A., Singh R., Rozett K., Modi N., Goldstein L. S., Roy T. A., Zhang F. J., Harvey R. G., Weyand E. H. 7H-benzo[c]fluorene: a major DNA adduct-forming component of coal tar. Carcinogenesis. 2000 Aug;21(8):1601–1609. doi: 10.1093/carcin/21.8.1601. [DOI] [PubMed] [Google Scholar]
  10. Neal J., Rigdon R. H. Gastric tumors in mice fed benzo(a)pyrene: a quantitative study. Tex Rep Biol Med. 1967 Winter;25(4):553–557. [PubMed] [Google Scholar]
  11. Stoner G. D., Greisiger E. A., Schut H. A., Pereira M. A., Loeb T. R., Klaunig J. E., Branstetter D. G. A comparison of the lung adenoma response in strain A/J mice after intraperitoneal and oral administration of carcinogens. Toxicol Appl Pharmacol. 1984 Feb;72(2):313–323. doi: 10.1016/0041-008x(84)90316-8. [DOI] [PubMed] [Google Scholar]

Articles from Environmental Health Perspectives are provided here courtesy of National Institute of Environmental Health Sciences

RESOURCES