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. 2002 Jan;110(1):23–28. doi: 10.1289/ehp.0211023

Exposure assessment to dioxins from the use of tampons and diapers.

Michael J DeVito 1, Arnold Schecter 1
PMCID: PMC1240689  PMID: 11781161

Abstract

Over the past several years there has been concern over exposure to dioxins through the use of tampons and other sanitary products. This article describes attempts to estimate dioxin exposures from tampons and infant diapers; we then compare exposure estimates to dietary dioxin exposures. We analyzed four brands of tampons and four brands of infant diapers obtained from commercial establishments in San Francisco, California, for dioxin concentrations. We estimated exposures to dioxins on the basis of a screening level analysis that assumed all dioxins present were completely absorbed. We also estimated exposures by using a more refined analysis that incorporates partition coefficients to estimate bioavailability. None of the products contained 2,3,7,8-tetrachlorodibenzo-p-dioxin, the most potent dioxin, although other dioxins were present at detectable concentrations in all samples. We observed minimal differences in the concentrations of dioxins between 100% cotton and cotton/pulp products. The refined exposure analysis indicates that exposures to dioxins from tampons are approximately 13,000-240,000 times less than dietary exposures. The refined exposure analysis showed that exposure to dioxins from the diet is more than 30,000-2,200,000 times the exposure through diapers in nursing infants. Although dioxins are found in trace amounts in both cotton and pulp sanitary products, exposure to dioxins through tampons and diapers does not significantly contribute to dioxin exposures in the United States.

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Selected References

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  1. Birnbaum L. S. The mechanism of dioxin toxicity: relationship to risk assessment. Environ Health Perspect. 1994 Nov;102 (Suppl 9):157–167. doi: 10.1289/ehp.94102s9157. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Cummings A. M., Hedge J. M., Birnbaum L. S. Effect of prenatal exposure to TCDD on the promotion of endometriotic lesion growth by TCDD in adult female rats and mice. Toxicol Sci. 1999 Nov;52(1):45–49. doi: 10.1093/toxsci/52.1.45. [DOI] [PubMed] [Google Scholar]
  3. Cummings A. M., Metcalf J. L., Birnbaum L. Promotion of endometriosis by 2,3,7,8-tetrachlorodibenzo-p-dioxin in rats and mice: time-dose dependence and species comparison. Toxicol Appl Pharmacol. 1996 May;138(1):131–139. doi: 10.1006/taap.1996.0106. [DOI] [PubMed] [Google Scholar]
  4. Eadon G., Kaminsky L., Silkworth J., Aldous K., Hilker D., O'Keefe P., Smith R., Gierthy J., Hawley J., Kim N. Calculation of 2,3,7,8-TCDD equivalent concentrations of complex environmental contaminant mixtures. Environ Health Perspect. 1986 Dec;70:221–227. doi: 10.1289/ehp.8670221. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Hahn M. E. The aryl hydrocarbon receptor: a comparative perspective. Comp Biochem Physiol C Pharmacol Toxicol Endocrinol. 1998 Nov;121(1-3):23–53. doi: 10.1016/s0742-8413(98)10028-2. [DOI] [PubMed] [Google Scholar]
  6. Henriksen G. L., Ketchum N. S., Michalek J. E., Swaby J. A. Serum dioxin and diabetes mellitus in veterans of Operation Ranch Hand. Epidemiology. 1997 May;8(3):252–258. doi: 10.1097/00001648-199705000-00005. [DOI] [PubMed] [Google Scholar]
  7. Johnson K. L., Cummings A. M., Birnbaum L. S. Promotion of endometriosis in mice by polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls. Environ Health Perspect. 1997 Jul;105(7):750–755. doi: 10.1289/ehp.97105750. [DOI] [PMC free article] [PubMed] [Google Scholar]
  8. Klasmeier J., Mühlebach A., McLachlan M. S. PCDD/Fs in textiles--part II: transfer from clothing to human skin. Chemosphere. 1999 Jan;38(1):97–108. doi: 10.1016/s0045-6535(98)00176-3. [DOI] [PubMed] [Google Scholar]
  9. Koninckx P. R., Braet P., Kennedy S. H., Barlow D. H. Dioxin pollution and endometriosis in Belgium. Hum Reprod. 1994 Jun;9(6):1001–1002. doi: 10.1093/oxfordjournals.humrep.a138623. [DOI] [PubMed] [Google Scholar]
  10. Koopman-Esseboom C., Weisglas-Kuperus N., de Ridder M. A., Van der Paauw C. G., Tuinstra L. G., Sauer P. J. Effects of polychlorinated biphenyl/dioxin exposure and feeding type on infants' mental and psychomotor development. Pediatrics. 1996 May;97(5):700–706. [PubMed] [Google Scholar]
  11. Lai T. J., Guo Y. L., Yu M. L., Ko H. C., Hsu C. C. Cognitive development in Yucheng children. Chemosphere. 1994 Nov-Dec;29(9-11):2405–2411. doi: 10.1016/0045-6535(94)90409-x. [DOI] [PubMed] [Google Scholar]
  12. Longnecker M. P., Michalek J. E. Serum dioxin level in relation to diabetes mellitus among Air Force veterans with background levels of exposure. Epidemiology. 2000 Jan;11(1):44–48. doi: 10.1097/00001648-200001000-00010. [DOI] [PubMed] [Google Scholar]
  13. Mayani A., Barel S., Soback S., Almagor M. Dioxin concentrations in women with endometriosis. Hum Reprod. 1997 Feb;12(2):373–375. doi: 10.1093/humrep/12.2.373. [DOI] [PubMed] [Google Scholar]
  14. Pesatori A. C., Zocchetti C., Guercilena S., Consonni D., Turrini D., Bertazzi P. A. Dioxin exposure and non-malignant health effects: a mortality study. Occup Environ Med. 1998 Feb;55(2):126–131. doi: 10.1136/oem.55.2.126. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rier S. E., Martin D. C., Bowman R. E., Dmowski W. P., Becker J. L. Endometriosis in rhesus monkeys (Macaca mulatta) following chronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin. Fundam Appl Toxicol. 1993 Nov;21(4):433–441. doi: 10.1006/faat.1993.1119. [DOI] [PubMed] [Google Scholar]
  16. Schecter A. A selective historical review of congener-specific human tissue measurements as sensitive and specific biomarkers of exposure to dioxins and related compounds. Environ Health Perspect. 1998 Apr;106 (Suppl 2):737–742. doi: 10.1289/ehp.98106737. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. Schecter A., Kassis I., Päpke O. Partitioning of dioxins, dibenzofurans, and coplanar PCBS in blood, milk, adipose tissue, placenta and cord blood from five American women. Chemosphere. 1998 Oct-Nov;37(9-12):1817–1823. doi: 10.1016/s0045-6535(98)00247-1. [DOI] [PubMed] [Google Scholar]
  18. Schecter A., Startin J., Wright C., Kelly M., Päpke O., Lis A., Ball M., Olson J. R. Congener-specific levels of dioxins and dibenzofurans in U.S. food and estimated daily dioxin toxic equivalent intake. Environ Health Perspect. 1994 Nov;102(11):962–966. doi: 10.1289/ehp.94102962. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Steenland K., Piacitelli L., Deddens J., Fingerhut M., Chang L. I. Cancer, heart disease, and diabetes in workers exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin. J Natl Cancer Inst. 1999 May 5;91(9):779–786. doi: 10.1093/jnci/91.9.779. [DOI] [PubMed] [Google Scholar]
  20. Umbreit T. H., Hesse E. J., Gallo M. A. Bioavailability of dioxin in soil from a 2,4,5-T manufacturing site. Science. 1986 Apr 25;232(4749):497–499. doi: 10.1126/science.3961492. [DOI] [PubMed] [Google Scholar]
  21. Van den Berg M., Birnbaum L., Bosveld A. T., Brunström B., Cook P., Feeley M., Giesy J. P., Hanberg A., Hasegawa R., Kennedy S. W. Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife. Environ Health Perspect. 1998 Dec;106(12):775–792. doi: 10.1289/ehp.98106775. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Yang J. Z., Agarwal S. K., Foster W. G. Subchronic exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin modulates the pathophysiology of endometriosis in the cynomolgus monkey. Toxicol Sci. 2000 Aug;56(2):374–381. doi: 10.1093/toxsci/56.2.374. [DOI] [PubMed] [Google Scholar]

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