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. 2002 Mar;110(3):293–300. doi: 10.1289/ehp.02110293

Effect of motor vehicle emissions on respiratory health in an urban area.

David L Buckeridge 1, Richard Glazier 1, Bart J Harvey 1, Michael Escobar 1, Carl Amrhein 1, John Frank 1
PMCID: PMC1240770  PMID: 11882481

Abstract

Motor vehicles emit particulate matter < 2.5 microm in diameter (PM(2.5)), and as a result, PM(2.5) concentrations tend to be elevated near busy streets. Studies of the relationship between motor vehicle emissions and respiratory health are generally limited by difficulties in exposure assessment. We developed a refined exposure model and implemented it using a geographic information system to estimate the average daily census enumeration area (EA) exposure to PM(2.5). Southeast Toronto, the study area, includes 334 EAs and covers 16 km(2) of urban area. We used hospital admission diagnostic codes from 1990 to 1992 to measure respiratory and genitourinary conditions. We assessed the effect of EA exposure on hospital admissions using a Poisson mixed-effects model and examined the spatial distributions of variables. Exposure to PM(2.5) has a significant effect on admission rates for a subset of respiratory diagnoses (asthma, bronchitis, chronic obstructive pulmonary disease, pneumonia, upper respiratory tract infection), with a relative risk of 1.24 (95% confidence interval, 1.05-1.45) for a log(10) increase in exposure. We noted a weaker effect of exposure on hospitalization for all respiratory conditions, and no effect on hospitalization for nonrespiratory conditions.

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Selected References

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  1. Abt E., Suh H. H., Allen G., Koutrakis P. Characterization of indoor particle sources: A study conducted in the metropolitan Boston area. Environ Health Perspect. 2000 Jan;108(1):35–44. doi: 10.1289/ehp.0010835. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. Brenner H., Savitz D. A., Jöckel K. H., Greenland S. Effects of nondifferential exposure misclassification in ecologic studies. Am J Epidemiol. 1992 Jan 1;135(1):85–95. doi: 10.1093/oxfordjournals.aje.a116205. [DOI] [PubMed] [Google Scholar]
  3. Brunekreef B., Janssen N. A., de Hartog J., Harssema H., Knape M., van Vliet P. Air pollution from truck traffic and lung function in children living near motorways. Epidemiology. 1997 May;8(3):298–303. doi: 10.1097/00001648-199705000-00012. [DOI] [PubMed] [Google Scholar]
  4. Burnett R. T., Cakmak S., Brook J. R., Krewski D. The role of particulate size and chemistry in the association between summertime ambient air pollution and hospitalization for cardiorespiratory diseases. Environ Health Perspect. 1997 Jun;105(6):614–620. doi: 10.1289/ehp.97105614. [DOI] [PMC free article] [PubMed] [Google Scholar]
  5. Burnett R. T., Dales R., Krewski D., Vincent R., Dann T., Brook J. R. Associations between ambient particulate sulfate and admissions to Ontario hospitals for cardiac and respiratory diseases. Am J Epidemiol. 1995 Jul 1;142(1):15–22. doi: 10.1093/oxfordjournals.aje.a117540. [DOI] [PubMed] [Google Scholar]
  6. Cain K. C., Diehr P. Testing the null hypothesis in small area analysis. Health Serv Res. 1992 Aug;27(3):267–294. [PMC free article] [PubMed] [Google Scholar]
  7. Clayton D., Kaldor J. Empirical Bayes estimates of age-standardized relative risks for use in disease mapping. Biometrics. 1987 Sep;43(3):671–681. [PubMed] [Google Scholar]
  8. Dockery D. W., Pope C. A., 3rd, Xu X., Spengler J. D., Ware J. H., Fay M. E., Ferris B. G., Jr, Speizer F. E. An association between air pollution and mortality in six U.S. cities. N Engl J Med. 1993 Dec 9;329(24):1753–1759. doi: 10.1056/NEJM199312093292401. [DOI] [PubMed] [Google Scholar]
  9. Edwards J., Walters S., Griffiths R. K. Hospital admissions for asthma in preschool children: relationship to major roads in Birmingham, United Kingdom. Arch Environ Health. 1994 Jul-Aug;49(4):223–227. doi: 10.1080/00039896.1994.9937471. [DOI] [PubMed] [Google Scholar]
  10. English P., Neutra R., Scalf R., Sullivan M., Waller L., Zhu L. Examining associations between childhood asthma and traffic flow using a geographic information system. Environ Health Perspect. 1999 Sep;107(9):761–767. doi: 10.1289/ehp.99107761. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Frohlich N., Mustard C. A regional comparison of socioeconomic and health indices in a Canadian province. Soc Sci Med. 1996 May;42(9):1273–1281. doi: 10.1016/0277-9536(95)00220-0. [DOI] [PubMed] [Google Scholar]
  12. Greenland S., Robins J. Invited commentary: ecologic studies--biases, misconceptions, and counterexamples. Am J Epidemiol. 1994 Apr 15;139(8):747–760. doi: 10.1093/oxfordjournals.aje.a117069. [DOI] [PubMed] [Google Scholar]
  13. HILL A. B. THE ENVIRONMENT AND DISEASE: ASSOCIATION OR CAUSATION? Proc R Soc Med. 1965 May;58:295–300. [PMC free article] [PubMed] [Google Scholar]
  14. Health effects of outdoor air pollution. Committee of the Environmental and Occupational Health Assembly of the American Thoracic Society. Am J Respir Crit Care Med. 1996 Jan;153(1):3–50. doi: 10.1164/ajrccm.153.1.8542133. [DOI] [PubMed] [Google Scholar]
  15. Keil U., Weiland S. K., Duhme H., Chambless L. The International Study of Asthma and Allergies in Childhood (ISAAC): objectives and methods; results from German ISAAC centres concerning traffic density and wheezing and allergic rhinitis. Toxicol Lett. 1996 Aug;86(2-3):99–103. doi: 10.1016/0378-4274(96)03680-6. [DOI] [PubMed] [Google Scholar]
  16. Künzli N., Kaiser R., Medina S., Studnicka M., Chanel O., Filliger P., Herry M., Horak F., Jr, Puybonnieux-Texier V., Quénel P. Public-health impact of outdoor and traffic-related air pollution: a European assessment. Lancet. 2000 Sep 2;356(9232):795–801. doi: 10.1016/S0140-6736(00)02653-2. [DOI] [PubMed] [Google Scholar]
  17. Livingstone A. E., Shaddick G., Grundy C., Elliott P. Do people living near inner city main roads have more asthma needing treatment? Case control study. BMJ. 1996 Mar 16;312(7032):676–677. doi: 10.1136/bmj.312.7032.676. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. Moschandreas D. J. Exposure to pollutants and daily time budgets of people. Bull N Y Acad Med. 1981 Dec;57(10):845–859. [PMC free article] [PubMed] [Google Scholar]
  19. Nitta H., Sato T., Nakai S., Maeda K., Aoki S., Ono M. Respiratory health associated with exposure to automobile exhaust. I. Results of cross-sectional studies in 1979, 1982, and 1983. Arch Environ Health. 1993 Jan-Feb;48(1):53–58. doi: 10.1080/00039896.1993.9938393. [DOI] [PubMed] [Google Scholar]
  20. Nurminen M. Linkage failures in ecological studies. World Health Stat Q. 1995;48(2):78–84. [PubMed] [Google Scholar]
  21. Oglesby L., Rotko T., Krütli P., Boudet C., Kruize H., Nen M. J., Künzli N. Personal exposure assessment studies may suffer from exposure-relevant selection bias. J Expo Anal Environ Epidemiol. 2000 May-Jun;10(3):251–266. doi: 10.1038/sj.jea.7500088. [DOI] [PubMed] [Google Scholar]
  22. Oosterlee A., Drijver M., Lebret E., Brunekreef B. Chronic respiratory symptoms in children and adults living along streets with high traffic density. Occup Environ Med. 1996 Apr;53(4):241–247. doi: 10.1136/oem.53.4.241. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. Ozkaynak H., Xue J., Spengler J., Wallace L., Pellizzari E., Jenkins P. Personal exposure to airborne particles and metals: results from the Particle TEAM study in Riverside, California. J Expo Anal Environ Epidemiol. 1996 Jan-Mar;6(1):57–78. [PubMed] [Google Scholar]
  24. Pope C. A., 3rd, Thun M. J., Namboodiri M. M., Dockery D. W., Evans J. S., Speizer F. E., Heath C. W., Jr Particulate air pollution as a predictor of mortality in a prospective study of U.S. adults. Am J Respir Crit Care Med. 1995 Mar;151(3 Pt 1):669–674. doi: 10.1164/ajrccm/151.3_Pt_1.669. [DOI] [PubMed] [Google Scholar]
  25. Roos L. L., Mustard C. A., Nicol J. P., McLerran D. F., Malenka D. J., Young T. K., Cohen M. M. Registries and administrative data: organization and accuracy. Med Care. 1993 Mar;31(3):201–212. doi: 10.1097/00005650-199303000-00002. [DOI] [PubMed] [Google Scholar]
  26. Rosenbaum P. R., Rubin D. B. Difficulties with regression analyses of age-adjusted rates. Biometrics. 1984 Jun;40(2):437–443. [PubMed] [Google Scholar]
  27. Samet J. M., Dominici F., Curriero F. C., Coursac I., Zeger S. L. Fine particulate air pollution and mortality in 20 U.S. cities, 1987-1994. N Engl J Med. 2000 Dec 14;343(24):1742–1749. doi: 10.1056/NEJM200012143432401. [DOI] [PubMed] [Google Scholar]
  28. Schwartz S. The fallacy of the ecological fallacy: the potential misuse of a concept and the consequences. Am J Public Health. 1994 May;84(5):819–824. doi: 10.2105/ajph.84.5.819. [DOI] [PMC free article] [PubMed] [Google Scholar]
  29. Twigg L. Health based geographical information systems: their potential examined in the light of existing data sources. Soc Sci Med. 1990;30(1):143–155. doi: 10.1016/0277-9536(90)90337-r. [DOI] [PubMed] [Google Scholar]
  30. Venn A., Lewis S., Cooper M., Hubbard R., Hill I., Boddy R., Bell M., Britton J. Local road traffic activity and the prevalence, severity, and persistence of wheeze in school children: combined cross sectional and longitudinal study. Occup Environ Med. 2000 Mar;57(3):152–158. doi: 10.1136/oem.57.3.152. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Vine M. F., Degnan D., Hanchette C. Geographic information systems: their use in environmental epidemiologic research. Environ Health Perspect. 1997 Jun;105(6):598–605. doi: 10.1289/ehp.97105598. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Waldron G., Pottle B., Dod J. Asthma and the motorways--one District's experience. J Public Health Med. 1995 Mar;17(1):85–89. [PubMed] [Google Scholar]
  33. Walter S. D. Assessing spatial patterns in disease rates. Stat Med. 1993 Oct;12(19-20):1885–1894. doi: 10.1002/sim.4780121914. [DOI] [PubMed] [Google Scholar]
  34. Walter S. D. The analysis of regional patterns in health data. I. Distributional considerations. Am J Epidemiol. 1992 Sep 15;136(6):730–741. doi: 10.1093/oxfordjournals.aje.a116552. [DOI] [PubMed] [Google Scholar]
  35. Walter S. D. The analysis of regional patterns in health data. II. The power to detect environmental effects. Am J Epidemiol. 1992 Sep 15;136(6):742–759. doi: 10.1093/oxfordjournals.aje.a116553. [DOI] [PubMed] [Google Scholar]
  36. Weiland S. K., Mundt K. A., Rückmann A., Keil U. Self-reported wheezing and allergic rhinitis in children and traffic density on street of residence. Ann Epidemiol. 1994 May;4(3):243–247. doi: 10.1016/1047-2797(94)90103-1. [DOI] [PubMed] [Google Scholar]
  37. Westerholm R., Egebäck K. E. Exhaust emissions from light- and heavy-duty vehicles: chemical composition, impact of exhaust after treatment, and fuel parameters. Environ Health Perspect. 1994 Oct;102 (Suppl 4):13–23. doi: 10.1289/ehp.94102s413. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Wilkins R. Use of postal codes and addresses in the analysis of health data. Health Rep. 1993;5(2):157–177. [PubMed] [Google Scholar]
  39. Wjst M., Reitmeir P., Dold S., Wulff A., Nicolai T., von Loeffelholz-Colberg E. F., von Mutius E. Road traffic and adverse effects on respiratory health in children. BMJ. 1993 Sep 4;307(6904):596–600. doi: 10.1136/bmj.307.6904.596. [DOI] [PMC free article] [PubMed] [Google Scholar]
  40. Wróbel A., Rokita E., Maenhaut W. Transport of traffic-related aerosols in urban areas. Sci Total Environ. 2000 Aug 10;257(2-3):199–211. doi: 10.1016/s0048-9697(00)00519-2. [DOI] [PubMed] [Google Scholar]
  41. van Vliet P., Knape M., de Hartog J., Janssen N., Harssema H., Brunekreef B. Motor vehicle exhaust and chronic respiratory symptoms in children living near freeways. Environ Res. 1997;74(2):122–132. doi: 10.1006/enrs.1997.3757. [DOI] [PubMed] [Google Scholar]

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