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. 2003 Jun;111(7):881–883. doi: 10.1289/ehp.6039

Nerve cell damage in mammalian brain after exposure to microwaves from GSM mobile phones.

Leif G Salford 1, Arne E Brun 1, Jacob L Eberhardt 1, Lars Malmgren 1, Bertil R R Persson 1
PMCID: PMC1241519  PMID: 12782486

Abstract

The possible risks of radio-frequency electromagnetic fields for the human body is a growing concern for our society. We have previously shown that weak pulsed microwaves give rise to a significant leakage of albumin through the blood-brain barrier. In this study we investigated whether a pathologic leakage across the blood-brain barrier might be combined with damage to the neurons. Three groups each of eight rats were exposed for 2 hr to Global System for Mobile Communications (GSM) mobile phone electromagnetic fields of different strengths. We found highly significant (p< 0.002) evidence for neuronal damage in the cortex, hippocampus, and basal ganglia in the brains of exposed rats.

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Selected References

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  1. Adey W. R., Byus C. V., Cain C. D., Higgins R. J., Jones R. A., Kean C. J., Kuster N., MacMurray A., Stagg R. B., Zimmerman G. Spontaneous and nitrosourea-induced primary tumors of the central nervous system in Fischer 344 rats chronically exposed to 836 MHz modulated microwaves. Radiat Res. 1999 Sep;152(3):293–302. [PubMed] [Google Scholar]
  2. Fritze K., Sommer C., Schmitz B., Mies G., Hossmann K. A., Kiessling M., Wiessner C. Effect of global system for mobile communication (GSM) microwave exposure on blood-brain barrier permeability in rat. Acta Neuropathol. 1997 Nov;94(5):465–470. doi: 10.1007/s004010050734. [DOI] [PubMed] [Google Scholar]
  3. Gruenau S. P., Oscar K. J., Folker M. T., Rapoport S. I. Absence of microwave effect on blood-brain barrier permeability to [14C]sucrose in the conscious rat. Exp Neurol. 1982 Feb;75(2):299–307. doi: 10.1016/0014-4886(82)90162-5. [DOI] [PubMed] [Google Scholar]
  4. Hardell L., Hallquist A., Mild K. Hansson, Carlberg M., Påhlson A., Lilja A. Cellular and cordless telephones and the risk for brain tumours. Eur J Cancer Prev. 2002 Aug;11(4):377–386. doi: 10.1097/00008469-200208000-00010. [DOI] [PubMed] [Google Scholar]
  5. Hassel B., Iversen E. G., Fonnum F. Neurotoxicity of albumin in vivo. Neurosci Lett. 1994 Feb 14;167(1-2):29–32. doi: 10.1016/0304-3940(94)91020-0. [DOI] [PubMed] [Google Scholar]
  6. Hyland G. J. Physics and biology of mobile telephony. Lancet. 2000 Nov 25;356(9244):1833–1836. doi: 10.1016/s0140-6736(00)03243-8. [DOI] [PubMed] [Google Scholar]
  7. Oscar K. J., Hawkins T. D. Microwave alteration of the blood-brain barrier system of rats. Brain Res. 1977 May 6;126(2):281–293. doi: 10.1016/0006-8993(77)90726-0. [DOI] [PubMed] [Google Scholar]
  8. Prato F. S., Frappier J. R., Shivers R. R., Kavaliers M., Zabel P., Drost D., Lee T. Y. Magnetic resonance imaging increases the blood-brain barrier permeability to 153-gadolinium diethylenetriaminepentaacetic acid in rats. Brain Res. 1990 Jul 23;523(2):301–304. doi: 10.1016/0006-8993(90)91502-8. [DOI] [PubMed] [Google Scholar]
  9. Repacholi M. H., Basten A., Gebski V., Noonan D., Finnie J., Harris A. W. Lymphomas in E mu-Pim1 transgenic mice exposed to pulsed 900 MHZ electromagnetic fields. Radiat Res. 1997 May;147(5):631–640. [PubMed] [Google Scholar]
  10. Salford L. G., Brun A., Sturesson K., Eberhardt J. L., Persson B. R. Permeability of the blood-brain barrier induced by 915 MHz electromagnetic radiation, continuous wave and modulated at 8, 16, 50, and 200 Hz. Microsc Res Tech. 1994 Apr 15;27(6):535–542. doi: 10.1002/jemt.1070270608. [DOI] [PubMed] [Google Scholar]
  11. Schirmacher A., Winters S., Fischer S., Goeke J., Galla H. J., Kullnick U., Ringelstein E. B., Stögbauer F. Electromagnetic fields (1.8 GHz) increase the permeability to sucrose of the blood-brain barrier in vitro. Bioelectromagnetics. 2000 Jul;21(5):338–345. [PubMed] [Google Scholar]
  12. Shivers R. R., Kavaliers M., Teskey G. C., Prato F. S., Pelletier R. M. Magnetic resonance imaging temporarily alters blood-brain barrier permeability in the rat. Neurosci Lett. 1987 Apr 23;76(1):25–31. doi: 10.1016/0304-3940(87)90186-8. [DOI] [PubMed] [Google Scholar]

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