Skip to main content
Environmental Health Perspectives logoLink to Environmental Health Perspectives
. 2003 Nov;111(14):1809–1818. doi: 10.1289/ehp.6200

Objectivity and ethics in environmental health science.

Steve Wing 1
PMCID: PMC1241729  PMID: 14594636

Abstract

During the past several decades, philosophers of science and scientists themselves have become increasingly aware of the complex ways in which scientific knowledge is shaped by its social context. This awareness has called into question traditional notions of objectivity. Working scientists need an understanding of their own practice that avoids the naïve myth that science can become objective by avoiding social influences as well as the reductionist view that its content is determined simply by economic interests. A nuanced perspective on this process can improve research ethics and increase the capacity of science to contribute to equitable public policy, especially in areas such as environmental and occupational health, which have direct implications for profits, regulation, legal responsibility, and social justice. I discuss research into health effects of the 1979 accident at Three Mile Island near Harrisburg, Pennsylvania, USA, as an example of how scientific explanations are shaped by social concepts, norms, and preconceptions. I describe how a scientific practice that developed under the influence of medical and nuclear physics interacted with observations made by exposed community members to affect research questions, the interpretation of evidence, inferences about biological mechanisms in disease causation, and the use of evidence in litigation. By considering the history and philosophy of their disciplines, practicing researchers can increase the rigor, objectivity, and social responsibility of environmental health science.

Full Text

The Full Text of this article is available as a PDF (701.8 KB).

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Appelbaum F. R. The influence of total dose, fractionation, dose rate, and distribution of total body irradiation on bone marrow transplantation. Semin Oncol. 1993 Aug;20(4 Suppl 4):3–11. [PubMed] [Google Scholar]
  2. Armstrong D. "Controversies in epidemiology", teaching causality in context at the University at Albany, School of Public Health. Scand J Public Health. 1999 Jun;27(2):81–84. [PubMed] [Google Scholar]
  3. Baum A., Cohen L., Hall M. Control and intrusive memories as possible determinants of chronic stress. Psychosom Med. 1993 May-Jun;55(3):274–286. doi: 10.1097/00006842-199305000-00005. [DOI] [PubMed] [Google Scholar]
  4. Baum A., Gatchel R. J., Schaeffer M. A. Emotional, behavioral, and physiological effects of chronic stress at Three Mile Island. J Consult Clin Psychol. 1983 Aug;51(4):565–572. doi: 10.1037//0022-006x.51.4.565. [DOI] [PubMed] [Google Scholar]
  5. Baum A. Stress, intrusive imagery, and chronic distress. Health Psychol. 1990;9(6):653–675. doi: 10.1037//0278-6133.9.6.653. [DOI] [PubMed] [Google Scholar]
  6. Beyea J. Geographic exposure modeling: a valuable extension of geographic information systems for use in environmental epidemiology. Environ Health Perspect. 1999 Feb;107 (Suppl 1):181–190. doi: 10.1289/ehp.99107s1181. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. Beyea J. Three Mile Island--six years later. J Nucl Med. 1985 Nov;26(11):1345–1346. [PubMed] [Google Scholar]
  8. Brodsky C. M. The psychiatric epidemic in the American workplace. Occup Med. 1988 Oct-Dec;3(4):653–662. [PubMed] [Google Scholar]
  9. Cleary P. D., Houts P. S. The psychological impact of the Three Mile Island incident. J Human Stress. 1984 Spring;10(1):28–34. doi: 10.1080/0097840X.1984.9934956. [DOI] [PubMed] [Google Scholar]
  10. Cornely P., Bromet E. Prevalence of behavior problems in three-year-old children living near Three Mile Island: a comparative analysis. J Child Psychol Psychiatry. 1986 Jul;27(4):489–498. doi: 10.1111/j.1469-7610.1986.tb00636.x. [DOI] [PubMed] [Google Scholar]
  11. Davidson L. M., Fleming R., Baum A. Chronic stress, catecholamines, and sleep disturbance at Three Mile Island. J Human Stress. 1987 Summer;13(2):75–83. doi: 10.1080/0097840X.1987.9936798. [DOI] [PubMed] [Google Scholar]
  12. Dew M. A., Bromet E. J. Predictors of temporal patterns of psychiatric distress during 10 years following the nuclear accident at Three Mile Island. Soc Psychiatry Psychiatr Epidemiol. 1993 Apr;28(2):49–55. doi: 10.1007/BF00802091. [DOI] [PubMed] [Google Scholar]
  13. Dew M. A., Bromet E. J., Schulberg H. C. A comparative analysis of two community stressors' long-term mental health effects. Am J Community Psychol. 1987 Apr;15(2):167–184. doi: 10.1007/BF00919277. [DOI] [PubMed] [Google Scholar]
  14. Dew M. A., Bromet E. J., Schulberg H. C., Dunn L. O., Parkinson D. K. Mental health effects of the Three Mile Island nuclear reactor restart. Am J Psychiatry. 1987 Aug;144(8):1074–1077. doi: 10.1176/ajp.144.8.1074. [DOI] [PubMed] [Google Scholar]
  15. Doll R. An epidemiological perspective of the biology of cancer. Cancer Res. 1978 Nov;38(11 Pt 1):3573–3583. [PubMed] [Google Scholar]
  16. Donnell H. D., Jr, Bagby J. R., Harmon R. G., Crellin J. R., Chaski H. C., Bright M. F., Van Tuinen M., Metzger R. W. Report of an illness outbreak at the Harry S Truman State Office Building. Am J Epidemiol. 1989 Mar;129(3):550–558. doi: 10.1093/oxfordjournals.aje.a115167. [DOI] [PubMed] [Google Scholar]
  17. Fabrikant J. I. The effects of the accident at Three Mile Island on the mental health and behavioral responses of the general population and nuclear workers. Health Phys. 1983 Sep;45(3):579–586. [PubMed] [Google Scholar]
  18. Faust H. S., Brilliant L. B. Is the diagnosis of "mass hysteria" an excuse for incomplete investigation of low-level environmental contamination? J Occup Med. 1981 Jan;23(1):22–26. doi: 10.1097/00043764-198101000-00013. [DOI] [PubMed] [Google Scholar]
  19. Field R. W., Field E. H., Zegers D. A., Steucek G. L. Iodine-131 in thyroids of the meadow vole (Microtus pennsylvanicus) in the vicinity of the Three Mile Island nuclear generating plant. Health Phys. 1981 Aug;41(2):297–301. doi: 10.1097/00004032-198108000-00007. [DOI] [PubMed] [Google Scholar]
  20. Gatchel R. J., Schaeffer M. A., Baum A. A psychophysiological field study of stress at Three Mile Island. Psychophysiology. 1985 Mar;22(2):175–181. doi: 10.1111/j.1469-8986.1985.tb01582.x. [DOI] [PubMed] [Google Scholar]
  21. Goldhaber M. K., Staub S. L., Tokuhata G. K. Spontaneous abortions after the Three Mile Island nuclear accident: a life table analysis. Am J Public Health. 1983 Jul;73(7):752–759. doi: 10.2105/ajph.73.7.752. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. Goldhaber M. K., Tokuhata G. K., Digon E., Caldwell G. G., Stein G. F., Lutz G., Gur D. The Three Mile Island Population Registry. Public Health Rep. 1983 Nov-Dec;98(6):603–609. [PMC free article] [PubMed] [Google Scholar]
  23. Greenberg M. The evolution of attitudes to the human hazards of ionizing radiation and to its investigators. Am J Ind Med. 1991;20(6):717–721. doi: 10.1002/ajim.4700200602. [DOI] [PubMed] [Google Scholar]
  24. Greenland S. Randomization, statistics, and causal inference. Epidemiology. 1990 Nov;1(6):421–429. doi: 10.1097/00001648-199011000-00003. [DOI] [PubMed] [Google Scholar]
  25. Hatch M. C., Beyea J., Nieves J. W., Susser M. Cancer near the Three Mile Island nuclear plant: radiation emissions. Am J Epidemiol. 1990 Sep;132(3):397–417. doi: 10.1093/oxfordjournals.aje.a115673. [DOI] [PubMed] [Google Scholar]
  26. Hatch M. C., Wallenstein S., Beyea J., Nieves J. W., Susser M. Cancer rates after the Three Mile Island nuclear accident and proximity of residence to the plant. Am J Public Health. 1991 Jun;81(6):719–724. doi: 10.2105/ajph.81.6.719. [DOI] [PMC free article] [PubMed] [Google Scholar]
  27. Hefez A. The role of the press and the medical community in the epidemic of "mysterious gas poisoning" in the Jordan West Bank. Am J Psychiatry. 1985 Jul;142(7):833–837. doi: 10.1176/ajp.142.7.833. [DOI] [PubMed] [Google Scholar]
  28. Holtzman E. Science, philosophy, and society: some recent books. Int J Health Serv. 1981;11(1):123–149. doi: 10.2190/L5EU-E7PC-HXG6-EUML. [DOI] [PubMed] [Google Scholar]
  29. Hornung R. W., Meinhardt T. J. Quantitative risk assessment of lung cancer in U.S. uranium miners. Health Phys. 1987 Apr;52(4):417–430. doi: 10.1097/00004032-198704000-00002. [DOI] [PubMed] [Google Scholar]
  30. Houts P. S., Tokuhata G. K., Bratz J., Bartholomew M. J., Sheffer K. W. Effect of pregnancy during TMI crisis on mothers' mental health and their child's development. Am J Public Health. 1991 Mar;81(3):384–386. doi: 10.2105/ajph.81.3.384. [DOI] [PMC free article] [PubMed] [Google Scholar]
  31. Janerich D. T. Can stress cause cancer? Am J Public Health. 1991 Jun;81(6):687–688. doi: 10.2105/ajph.81.6.687. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. Keller E. F. Between language and science: the question of directed mutation in molecular genetics. Perspect Biol Med. 1992 Winter;35(2):292–306. doi: 10.1353/pbm.1992.0000. [DOI] [PubMed] [Google Scholar]
  33. Langholz B., Thomas D., Xiang A., Stram D. Latency analysis in epidemiologic studies of occupational exposures: application to the Colorado Plateau uranium miners cohort. Am J Ind Med. 1999 Mar;35(3):246–256. doi: 10.1002/(sici)1097-0274(199903)35:3<246::aid-ajim4>3.0.co;2-6. [DOI] [PubMed] [Google Scholar]
  34. Lyon J. L. Nuclear weapons testing and research efforts to evaluate health effects on exposed populations in the United States. Epidemiology. 1999 Sep;10(5):557–560. doi: 10.1097/00001648-199909000-00017. [DOI] [PubMed] [Google Scholar]
  35. Mangano J. J. Low-level radiation harmed humans near Three Mile Island. Environ Health Perspect. 1997 Aug;105(8):786–787. doi: 10.1289/ehp.97105786. [DOI] [PMC free article] [PubMed] [Google Scholar]
  36. McCally Michael, Cassel Christine, Kimball Daryl G. U.S. government-sponsored radiation research on humans 1945-1975. Med Glob Surviv. 1994 Mar;1(1):4–17. [PubMed] [Google Scholar]
  37. McKinnon W., Weisse C. S., Reynolds C. P., Bowles C. A., Baum A. Chronic stress, leukocyte subpopulations, and humoral response to latent viruses. Health Psychol. 1989;8(4):389–402. doi: 10.1037//0278-6133.8.4.389. [DOI] [PubMed] [Google Scholar]
  38. Merwin S. E., Moeller D. W., Kennedy W. E., Jr, Moeller M. P. Application of the Supreme Court's Daubert criteria in radiation litigation. Health Phys. 2001 Dec;81(6):670–677. doi: 10.1097/00004032-200112000-00017. [DOI] [PubMed] [Google Scholar]
  39. Morgan K. Z. Health physics: its development, successes, failures, and eccentricities. Am J Ind Med. 1992;22(1):125–133. doi: 10.1002/ajim.4700220112. [DOI] [PubMed] [Google Scholar]
  40. Nussbaum R. H., Köhnlein W. Inconsistencies and open questions regarding low-dose health effects of ionizing radiation. Environ Health Perspect. 1994 Aug;102(8):656–667. doi: 10.1289/ehp.94102656. [DOI] [PMC free article] [PubMed] [Google Scholar]
  41. Nussbaum R. H. The linear no-threshold dose-effect relation: is it relevant to radiation protection regulation? Med Phys. 1998 Mar;25(3):291–300. doi: 10.1118/1.598210. [DOI] [PubMed] [Google Scholar]
  42. Prince-Embury S., Rooney J. F. Psychological symptoms of residents in the aftermath of the Three Mile Island nuclear accident and restart. J Soc Psychol. 1988 Dec;128(6):779–790. doi: 10.1080/00224545.1988.9924556. [DOI] [PubMed] [Google Scholar]
  43. Rothman K. J. Statistics in nonrandomized studies. Epidemiology. 1990 Nov;1(6):417–418. doi: 10.1097/00001648-199011000-00001. [DOI] [PubMed] [Google Scholar]
  44. Schaeffer M. A., Baum A. Adrenal cortical response to stress at Three Mile Island. Psychosom Med. 1984 May-Jun;46(3):227–237. doi: 10.1097/00006842-198405000-00005. [DOI] [PubMed] [Google Scholar]
  45. Simon G. E., Katon W. J., Sparks P. J. Allergic to life: psychological factors in environmental illness. Am J Psychiatry. 1990 Jul;147(7):901–906. doi: 10.1176/ajp.147.7.901. [DOI] [PubMed] [Google Scholar]
  46. Small G. W., Borus J. F. The influence of newspaper reports on outbreaks of mass hysteria. Psychiatr Q. 1987 Winter;58(4):269–278. doi: 10.1007/BF01064608. [DOI] [PubMed] [Google Scholar]
  47. Sterling T. D. The health effects of low-dose radiation on atomic workers. A case study of employer-directed research. Int J Health Serv. 1980;10(1):37–46. doi: 10.2190/TEDB-E2YU-5CQQ-01NR. [DOI] [PubMed] [Google Scholar]
  48. Stewart A. M., Kneale G. W. An overview of the Hanford controversy. Occup Med. 1991 Oct-Dec;6(4):641–663. [PubMed] [Google Scholar]
  49. Stewart A. The role of epidemiology in the detection of harmful effects of radiation. Environ Health Perspect. 2000 Feb;108(2):93–96. doi: 10.1289/ehp.0010893. [DOI] [PMC free article] [PubMed] [Google Scholar]
  50. Susser M. Consequences of the 1979 Three Mile Island accident continued: further comment. Environ Health Perspect. 1997 Jun;105(6):566–570. doi: 10.1289/ehp.105-1470087. [DOI] [PMC free article] [PubMed] [Google Scholar]
  51. Talbott E. O., Youk A. O., McHugh K. P., Shire J. D., Zhang A., Murphy B. P., Engberg R. A. Mortality among the residents of the Three Mile Island accident area: 1979-1992. Environ Health Perspect. 2000 Jun;108(6):545–552. doi: 10.1289/ehp.00108545. [DOI] [PMC free article] [PubMed] [Google Scholar]
  52. Talbott Evelyn O., Youk Ada O., McHugh-Pemu Kathleen P., Zborowski Jeanne V. Long-term follow-up of the residents of the Three Mile Island accident area: 1979-1998. Environ Health Perspect. 2003 Mar;111(3):341–348. doi: 10.1289/ehp.5662. [DOI] [PMC free article] [PubMed] [Google Scholar]
  53. Thomas J. P. Rebuilding trust in established institutions. Health Phys. 2001 Apr;80(4):379–383. doi: 10.1097/00004032-200104000-00015. [DOI] [PubMed] [Google Scholar]
  54. Wahlen M., Kunz C. O., Matuszek J. M., Mahoney W. E., Thompson R. C. Radioactive plume from the Three Mile Island accident: xenon-133 in air at a distance of 375 kilometers. Science. 1980 Feb 8;207(4431):639–640. doi: 10.1126/science.7352276. [DOI] [PubMed] [Google Scholar]
  55. Wilkinson G. S. Seven years in search of alpha: the best of times, the worst of times. Epidemiology. 1999 May;10(3):340–344. doi: 10.1097/00001648-199905000-00025. [DOI] [PubMed] [Google Scholar]
  56. Wing S., Richardson D., Armstrong D., Crawford-Brown D. A reevaluation of cancer incidence near the Three Mile Island nuclear plant: the collision of evidence and assumptions. Environ Health Perspect. 1997 Jan;105(1):52–57. doi: 10.1289/ehp.9710552. [DOI] [PMC free article] [PubMed] [Google Scholar]
  57. Wing S., Richardson D., Armstrong D. Reply to comments on "A reevaluation of cancer incidence near the Three Mile Island". Environ Health Perspect. 1997 Mar;105(3):266–268. doi: 10.1289/ehp.105-1469992. [DOI] [PMC free article] [PubMed] [Google Scholar]
  58. Wing S., Richardson D. Collision of evidence and assumptions: TMI déjà view. Environ Health Perspect. 2000 Dec;108(12):A546–A549. doi: 10.1289/ehp.108-a546b. [DOI] [PMC free article] [PubMed] [Google Scholar]
  59. Wing S., Richardson D., Stewart A. The relevance of occupational epidemiology to radiation protection standards. New Solut. 1999;9(2):133–151. doi: 10.2190/LBN7-2UAB-NJMQ-HDHA. [DOI] [PubMed] [Google Scholar]
  60. Wing S., Shy C. M., Wood J. L., Wolf S., Cragle D. L., Frome E. L. Mortality among workers at Oak Ridge National Laboratory. Evidence of radiation effects in follow-up through 1984. JAMA. 1991 Mar 20;265(11):1397–1402. [PubMed] [Google Scholar]
  61. Wing S., West C. M., Wood J. L., Tankersley W. Recording of external radiation exposures at Oak Ridge National Laboratory: implications for epidemiological studies. J Expo Anal Environ Epidemiol. 1994 Jan-Mar;4(1):83–93. [PubMed] [Google Scholar]

Articles from Environmental Health Perspectives are provided here courtesy of National Institute of Environmental Health Sciences

RESOURCES