To the Editor,
We would like to thank the authors1 for their interest in our study. We agree that using sedative agents might mask the effect of nitroglycerine and make the interpretation of the results difficult. However, our main aim in using sedative agents was to decrease the pain while inserting the sheath rather than preventing radial artery spasm. Secondly, the percentage of sedative medication usage between the groups was similar as presented in Table 2 (41.5% vs. 46.5%, P = .510).2
On the other hand, there are well-documented risk factors for radial artery complications. However, in our study, we did not analyze all the predictors of radial artery complications. Thus, we did not need to perform a logistic regression analysis. We also totally agree that well-designed, large-scale, prospective, randomized studies are needed to delineate this issue.
Funding Statement
The authors declare that this study received no financial support.
Footnotes
Declaration of Interests: The authors have no conflicts of interest to declare.
References
- 1. Naser A. Effects of nitroglycerin on the outcome of percutaneous coronary interventions via distal radial approach. Anatol J Cardiol. 2025;29(9):517-518. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 2. Karaca M, Dağdeviren B. Impact of nitroglycerine injection on radial artery outcomes in distal transradial access. Anatol J Cardiol. 2025;29(3):139 144. ( 10.14744/AnatolJCardiol.2025.4877) [DOI] [PMC free article] [PubMed] [Google Scholar]

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