Abstract
As high-throughput technologies in genomics, transcriptomics, and proteomics evolve, questions arise about their use in the assessment of occupational cancers. To address these questions, the National Institute for Occupational Safety and Health, the National Cancer Institute, the National Institute of Environmental Health Sciences, and the American Chemistry Council sponsored a workshop 8-9 May 2002 in Washington, DC. The workshop brought together 80 international specialists whose objective was to identify the means for best exploiting new technologies to enhance methods for laboratory investigation, epidemiologic evaluation, risk assessment, and prevention of occupational cancer. The workshop focused on identifying and interpreting markers for early biologic effect and inherited modifiers of risk.
Full Text
The Full Text of this article is available as a PDF (105.2 KB).
Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- Bonassi S., Hagmar L., Strömberg U., Montagud A. H., Tinnerberg H., Forni A., Heikkilä P., Wanders S., Wilhardt P., Hansteen I. L. Chromosomal aberrations in lymphocytes predict human cancer independently of exposure to carcinogens. European Study Group on Cytogenetic Biomarkers and Health. Cancer Res. 2000 Mar 15;60(6):1619–1625. [PubMed] [Google Scholar]
- Giardiello F. M., Brensinger J. D., Petersen G. M., Luce M. C., Hylind L. M., Bacon J. A., Booker S. V., Parker R. D., Hamilton S. R. The use and interpretation of commercial APC gene testing for familial adenomatous polyposis. N Engl J Med. 1997 Mar 20;336(12):823–827. doi: 10.1056/NEJM199703203361202. [DOI] [PubMed] [Google Scholar]
- Henry Carol J., Phillips Richard, Carpanini Francis, Corton J. Christopher, Craig Katherine, Igarashi Koichi, Leboeuf Robert, Marchant Gary, Osborn Kimberly, Pennie William D. Use of genomics in toxicology and epidemiology: findings and recommendations of a workshop. Environ Health Perspect. 2002 Oct;110(10):1047–1050. doi: 10.1289/ehp.021101047. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Ward Elizabeth M., Schulte Paul A., Bayard Steve, Blair Aaron, Brandt-Rauf Paul, Butler Mary Ann, Dankovic David, Hubbs Ann F., Jones Carol, Karstadt Myra. Priorities for development of research methods in occupational cancer. Environ Health Perspect. 2003 Jan;111(1):1–12. doi: 10.1289/ehp.111-1241299. [DOI] [PMC free article] [PubMed] [Google Scholar]