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Technology in Cancer Research & Treatment logoLink to Technology in Cancer Research & Treatment
. 2025 Sep 9;24:15330338251377135. doi: 10.1177/15330338251377135

Retraction: “Mir-452-3p: A Potential Tumor Promoter That Targets the CPEB3/EGFR Axis in Human Hepatocellular Carcinoma”

PMCID: PMC12420964  PMID: 40924819

At the request of Sage and the Editors, the following article has been retracted:

Tang H, Zhang J, Yu Z, et al. Mir-452-3p: A Potential Tumor Promoter That Targets the CPEB3/EGFR Axis in Human Hepatocellular Carcinoma. Technology in Cancer Research & Treatment. 2017;16(6):1136-1149. doi:10.1177/1533034617735931

The Executive Editor was notified of concerns raised on PubPeer regarding this article:

A) Concerns were raised that the β-actin row in Figure 9B appears highly similar to

The GAPDH row in Figure 1D of Chen et al.1

The GAPDH row in Figure 1D of Yin et al.2

B) The β-actin row in Figure 9A appears highly similar to

The GAPDH row in Figure 8C of Wu et al.3

The GAPDH row in Figure 6B of Wu et al.4

C) Figure 2B NC mimic panel and the Mimic panel of the Huh-7 group appear highly similar to Figure 6F’s PcDNA3.1 panel of the HepG2 group.

D) Figure 6F PcDNA3.1-CPEB3 panel of the HepG2 group appears highly similar to the control panel of the Huh-7 group.

The authors did not provide their raw data and could not explain the anomalies in these figures.

Due to the unexplained anomalies in the figures and data in this research, that call into question the overall integrity of the research, the article has been retracted.

The authors did not respond when notified of this retraction decision.

Works Cited

1. Retraction in: Biosci Rep. 2023 Mar 31;43(3): PMID: 28487475; PMCID: PMC5463266.Chen X, Yue B, Zhang C, Qi M, Qiu J, Wang Y, Chen J. MiR-130a-3p inhibits the viability, proliferation, invasion, and cell cycle, and promotes apoptosis of nasopharyngeal carcinoma cells by suppressing BACH2 expression. Biosci Rep. 2017 Jun 8;37(3):BSR20160576. doi: 10.1042/BSR20160576.

2. Yin Q, Wang J, Fu Q, Gu S, Rui Y.CircRUNX2 through has-miR-203 regulates RUNX2 toprevent osteoporosis.J Cell Mol Med. 2018;22:6112–6121.https://doi.org/10.1111/jcmm.13888YINET AL.|6121

3. Wu, Z., Huang, W., Wang, X. et al. Circular RNA CEP128 acts as a sponge of miR-145-5p in promoting the bladder cancer progression via regulating SOX11. Mol Med 24, 40 (2018). https://doi.org/10.1186/s10020-018-0039-0

4. RETRACTED: Wu D-M, Wang S, Wen X, et al.MircoRNA-1275 promotes proliferation, invasion andmigration of glioma cells via SERPINE1.J Cell Mol Med.2018;22:4963–4974.https://doi.org/10.1111/jcmm.137604974


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