To the Editor We have read with great interest the case of caffeine intoxication reported by Yoshimine et al., in which the theophylline level served as an indicator of treatment, and the caffeine level was measured (1). Based on our reading, we found that it is important to consider the clinical management of caffeine intoxication.
With reference to the findings reported in this paper, we feel we can make several contributions to the discussion. The literature indicates a growing body of evidence pointing to an increase in the consumption of caffeinated drinks among two specific categories of subjects: young people, particularly athletes, and healthcare workers (2,3). This trend suggests that young individuals, possibly motivated by factors such as energy enhancement and performance improvement, consume more caffeinated beverages than others (2). The literature also suggests an increase in the consumption of caffeinated drinks among healthcare workers, a trend that could be influenced by the demanding nature of healthcare professionals with long and irregular work hours (2,3).
Although moderate caffeine consumption is generally considered safe for most individuals, excessive intake can have adverse health effects (2,4,5).
In clinical practice, the management of caffeine intoxication involves addressing symptoms and, in severe cases, providing supportive care. There is no specific antidote for caffeine intoxication; therefore, treatment generally focuses on symptom relief.
The specific dosage of caffeine that leads to intoxication can vary from person to person, based on factors such as individual sensitivity and tolerance (1).
If caffeine intoxication is suspected, it is crucial to consider the severity of the symptoms and the amount of caffeine ingested. Common symptoms of caffeine intoxication include restlessness, insomnia, increased heart rate, muscle twitching, gastrointestinal disturbances, and more severe symptoms, such as seizures in extreme cases.
We appreciate Yoshimine et al., who highlighted in their manuscript the usefulness of the dosage of theophylline and caffeine in the management of subjects in whom intoxication is suspected (1).
The dosage of theophylline and caffeine is a very useful tool for the management and therapy of patients with intoxication to verify the effectiveness of the treatment. When caffeine intoxication is suspected, it is crucial to consider the severity of symptoms and amount of caffeine ingested.
We agree with Yoshimine et al. that the use of serial dosages can make treatment more effective by preventing the appearance of important and dangerous cardiovascular side effects, such as arrhythmias.
The authors state that they have no Conflict of Interest (COI).
References
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