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. 1993 Jan;217(1):64–71. doi: 10.1097/00000658-199301000-00011

Endorectal ultrasound for control of preoperative radiotherapy of rectal cancer.

F Glaser 1, C Kuntz 1, P Schlag 1, C Herfarth 1
PMCID: PMC1242735  PMID: 8424703

Abstract

Endorectal ultrasound (EUS) is known to be a reliable method for preoperative staging of rectal tumors. In this study, EUS was used to select patients with rectal cancer suitable for preoperative radiation therapy. By performing EUS before and after radiation, the aim of the study was to evaluate the role of EUS in monitoring the effects of preoperative radiation therapy. In 17 patients with large T3 or T4 rectal tumors, a complete staging by EUS was done before and after radiation therapy. Beside a shrinkage of the tumor, there was a change of echopattern to more hyperechoic gray levels to be observed in the irradiated tumor. The rectal wall lost its normal architecture, and lymph nodes disappeared or changed their echopattern from echopoor to echorich. There was no down-staging of a tumor seen by EUS. Complete preoperative staging was correct in 13 of 17 patients because of endosonographic examination before and after preoperative radiation therapy. New interpretation criteria are given for evaluation of patients with rectal cancer treated by radiation therapy.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Beynon J. An evaluation of the role of rectal endosonography in rectal cancer. Ann R Coll Surg Engl. 1989 Mar;71(2):131–139. [PMC free article] [PubMed] [Google Scholar]
  2. Beynon J., Mortensen N. J., Foy D. M., Channer J. L., Rigby H., Virjee J. Preoperative assessment of mesorectal lymph node involvement in rectal cancer. Br J Surg. 1989 Mar;76(3):276–279. doi: 10.1002/bjs.1800760320. [DOI] [PubMed] [Google Scholar]
  3. Boscaini M., Masoni L., Montori A. Transrectal ultrasonography: three years' experience. Int J Colorectal Dis. 1986 Oct;1(4):208–211. doi: 10.1007/BF01648338. [DOI] [PubMed] [Google Scholar]
  4. Cohen A. M. Has preoperative radiation therapy for resectable rectal cancer been proven effective? J Surg Oncol. 1990 Oct;45(2):69–71. doi: 10.1002/jso.2930450203. [DOI] [PubMed] [Google Scholar]
  5. Feifel G., Hildebrandt U., Dhom G. Die endorectale Sonographie beim Rectumcarcinom. Chirurg. 1985 Jun;56(6):398–402. [PubMed] [Google Scholar]
  6. Glaser F., Friedl P., von Ditfurth B., Schlag P., Herfarth C. Influence of endorectal ultrasound on surgical treatment of rectal cancer. Eur J Surg Oncol. 1990 Aug;16(4):304–311. [PubMed] [Google Scholar]
  7. Glaser F., Kleikamp G., Schlag P., Möller P., Herfarth C. Die Endosonographie in der präoperativen Beurteilung rectaler Tumoren. Chirurg. 1989 Dec;60(12):856–861. [PubMed] [Google Scholar]
  8. Glaser F., Layer G., Zuna I., van Kaick G., Schlag P., Herfarth C. Präoperative Beurteilung pararectaler Lymphknoten durch Ultraschall. Chirurg. 1990 Aug;61(8):587–591. [PubMed] [Google Scholar]
  9. Glaser F., Schlag P., Herfarth C. Endorectal ultrasonography for the assessment of invasion of rectal tumours and lymph node involvement. Br J Surg. 1990 Aug;77(8):883–887. doi: 10.1002/bjs.1800770813. [DOI] [PubMed] [Google Scholar]
  10. Gérard A., Buyse M., Nordlinger B., Loygue J., Pène F., Kempf P., Bosset J. F., Gignoux M., Arnaud J. P., Desaive C. Preoperative radiotherapy as adjuvant treatment in rectal cancer. Final results of a randomized study of the European Organization for Research and Treatment of Cancer (EORTC). Ann Surg. 1988 Nov;208(5):606–614. doi: 10.1097/00000658-198811000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. Horn A., Halvorsen J. F., Dahl O. Preoperative radiotherapy in operable rectal cancer. Dis Colon Rectum. 1990 Oct;33(10):823–828. doi: 10.1007/BF02051916. [DOI] [PubMed] [Google Scholar]
  12. Horn A., Morild I., Dahl O. Tumour shrinkage and down staging after preoperative radiation of rectal adenocarcinomas. Radiother Oncol. 1990 May;18(1):19–28. doi: 10.1016/0167-8140(90)90019-s. [DOI] [PubMed] [Google Scholar]
  13. Napoleon B., Pujol B., Berger F., Valette P. J., Gerard J. P., Souquet J. C. Accuracy of endosonography in the staging of rectal cancer treated by radiotherapy. Br J Surg. 1991 Jul;78(7):785–788. doi: 10.1002/bjs.1800780707. [DOI] [PubMed] [Google Scholar]
  14. Påhlman L., Glimelius B. Pre- or postoperative radiotherapy in rectal and rectosigmoid carcinoma. Report from a randomized multicenter trial. Ann Surg. 1990 Feb;211(2):187–195. doi: 10.1097/00000658-199002000-00011. [DOI] [PMC free article] [PubMed] [Google Scholar]
  15. Rifkin M. D., Ehrlich S. M., Marks G. Staging of rectal carcinoma: prospective comparison of endorectal US and CT. Radiology. 1989 Feb;170(2):319–322. doi: 10.1148/radiology.170.2.2643135. [DOI] [PubMed] [Google Scholar]
  16. Sarashina H., Inoue I., Saitoh N., Nunomura M., Nakayama H., Okui K. Untersuchung zur präoperativen Strahlentherapie beim Rektumkarzinom. Teil 2: Einfluss der Bestrahlung auf den Lymphknotenbefall. Strahlenther Onkol. 1991 Jun;167(6):361–365. [PubMed] [Google Scholar]

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