Author Correction: cuteFC: regenotyping structural variants through an accurate and efficient force-calling method

Author Correction: Genome Biol 26, 166 (2025)

https://doi.org/10.1186/s13059-025-03642-2

Following publication of the original article [1], the authors identified three errors in Methods and Funding, and Fig. 2D.

1. In the original version, the total number of simulated structural variations was incorrectly stated as 3,668 in the Process the benchmarking datasets part of Methods section. The correct sum of the simulated SVs: 2,191 insertions, 1,333 deletions, 450 inversions, 450 duplications, and 250 inter-chromosomal translocations, should be 4,674.

The original version was: “For the simulation datasets, we first simulated 3668 structural variations on chromosomes 1 and 2, including 2191 insertions, 1333 deletions, 450 inversions, 450 duplications, and 250 inter-chromosomal translocations, and reconstructed the reference genome GRCh38 with these SVs for the donor genome.”

The corrected version was: “For the simulation datasets, we first simulated 4674 structural variations on chromosomes 1 and 2, including 2191 insertions, 1333 deletions, 450 inversions, 450 duplications, and 250 inter-chromosomal translocations, and reconstructed the reference genome GRCh38 with these SVs for the donor genome”. The change was marked as bold. This correction does not affect the study’s results or conclusions.

2. In the Funding section, there contained redundant text, with the same grant details repeated in two separate paragraphs. We removed the duplicated paragraph and preserved the original content in the first paragraph.

The original version was: “This work has been supported by the National Key R&D Program of China (Grant number 2022YFF1202101, 2024YFC3406303, 2017YFC0907503), the National Natural Science Foundation of China (Grant number 62472120, 62331012), China Postdoctoral Science Foundation (Grant Number 2022M720965), and Heilongjiang Postdoctoral Foundation (Grant Number LBH-Z22174).

National Key Research and Development Program of China, 2024YFC3406303, 2022YFF1202101, 2017YFC0907503, National Natural Science Foundation of China, 62472120, 62331012, China Postdoctoral Science Foundation, 2022M720965, Heilongjiang Postdoctoral Science Foundation, LBH-Z22174”.

The corrected version was: “This work has been supported by the National Key R&D Program of China (Grant number 2022YFF1202101, 2024YFC3406303, 2017YFC0907503), the National Natural Science Foundation of China (Grant number 62472120, 62331012), China Postdoctoral Science Foundation (Grant Number 2022M720965), and Heilongjiang Postdoctoral Foundation (Grant Number LBH-Z22174)”.

The deleted paragraph was marked as bold. This correction only removes the duplicated funding, and does not alter the funding sources or their attribution.

3. In the left portion of Fig. 2D, the proportion of simulated reads for alternative alleles to simulated reads for reference alleles was incorrectly reversed. In the original version, the proportions were listed as “10:0, 9:1, 8:2, …, 2:8, 1:9, 0:10” from top to bottom. However, as described in the figure legend, the top zygosity corresponds to homozygous reference alleles, while the bottom zygosity represents homozygous alternative alleles. Therefore, the proportions should instead be listed in reverse order as “0:10, 1:9, 2:8, …, 8:2, 9:1, 10:0”. This correction ensures consistency in the presentation of allele proportions throughout the manuscript. The reverse of these values does not affect any other data in the figure or its conclusions.

The original Fig. 2 was:

The corrected Fig. 2 is:

The original article [1] has been corrected.