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. 1962 Apr;83(1):52–63. doi: 10.1042/bj0830052

Behaviour of some derivatives of 7-aminocephalosporanic acid and 6-aminopenicillanic acid as substrates, inhibitors and inducers of penicillinases

Brenda Crompton 1, Margaret Jago 1, Kathleen Crawford 1, G G F Newton 1, E P Abraham 1
PMCID: PMC1243507  PMID: 13882319

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ABRAHAM E. P., NEWTON G. G. A comparison of the action of penicillinase on benzylpenicillin and cephalosporin N and the competitive inhibition of penicillinase by cephalosporin C. Biochem J. 1956 Aug;63(4):628–634. doi: 10.1042/bj0630628. [DOI] [PMC free article] [PubMed] [Google Scholar]
  2. ABRAHAM E. P., NEWTON G. G. New penicillins, cephalosporin C, and penicillinase. Endeavour. 1961 Apr;20:92–100. [PubMed] [Google Scholar]
  3. ABRAHAM E. P., NEWTON G. G. The structure of cephalesporin C. Biochem J. 1961 May;79:377–393. doi: 10.1042/bj0790377. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. BATCHELOR F. R., DOYLE F. P., NAYLER J. H., ROLINSON G. N. Synthesis of penicillin: 6-aminopenicillanic acid in penicillin fermentations. Nature. 1959 Jan 24;183(4656):257–258. doi: 10.1038/183257b0. [DOI] [PubMed] [Google Scholar]
  5. CRAWFORD K., ABRAHAM E. P. The synergistic action of cephalosporin C and benzylpenicillin against a penicillinase-producing strain of Staphylococcus aureus. J Gen Microbiol. 1957 Jun;16(3):604–613. doi: 10.1099/00221287-16-3-604. [DOI] [PubMed] [Google Scholar]
  6. HALE C. W., NEWTON G. G., ABRAHAM E. P. Derivatives of cephalosporin C formed with certain heterocyclic tertiary bases. The cephalosporin C-A family. Biochem J. 1961 May;79:403–408. doi: 10.1042/bj0790403. [DOI] [PMC free article] [PubMed] [Google Scholar]
  7. HOFSTEE B. H. Non-inverted versus inverted plots in enzyme kinetics. Nature. 1959 Oct 24;184:1296–1298. doi: 10.1038/1841296b0. [DOI] [PubMed] [Google Scholar]
  8. JEFFERY J. D., ABRAHAM E. P., NEWTON G. G. Deacetylcephalosporin C. Biochem J. 1961 Dec;81:591–596. doi: 10.1042/bj0810591. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. KAY D., FILDES P. The calcium requirement of a typhoid bacteriophage. Br J Exp Pathol. 1950 Jun;31(3):338–348. [PMC free article] [PubMed] [Google Scholar]
  10. KOGUT M., POLLOCK M. R., TRIDGELL E. J. Purification of penicillin-induced penicillinase of Bacillus cereus NRRL 569: a comparison of its properties with those of a similarly purified penicillinase produced spontaneously by a constitutive mutant strain. Biochem J. 1956 Mar;62(3):391–401. doi: 10.1042/bj0620391. [DOI] [PMC free article] [PubMed] [Google Scholar]
  11. LODER B., NEWTON G. G., ABRAHAM E. P. The cephalosporin C nucleus (7-aminocephalosporanic acid) and some of its derivatives. Biochem J. 1961 May;79:408–416. doi: 10.1042/bj0790408. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. MOAT A. G., CECI L. N., BONDI A. Effect of cephalosporin C and various penicillin derivatives on staphylococcal penicillinase and penicillinase-producing Staphylococci. Proc Soc Exp Biol Med. 1961 Jul;107:675–677. doi: 10.3181/00379727-107-26725. [DOI] [PubMed] [Google Scholar]
  13. POLLOCK M. R. Penicillinase adaptation in B. cereus; adaptive enzyme formation in the absence of free substrate. Br J Exp Pathol. 1950 Dec;31(6):739–753. [PMC free article] [PubMed] [Google Scholar]
  14. POLLOCK M. R. Penicillinase adaptation in Bacillus cereus; an analysis of three phases in the response of logarithmically growing cultures to induction of penicillinase formation by penicillin. Br J Exp Pathol. 1952 Dec;33(6):587–600. [PMC free article] [PubMed] [Google Scholar]
  15. POLLOCK M. R., TORRIANI A. M. Purification et caractéristiques physicochimiques de la pénicillinase de Bacillus cereus. C R Hebd Seances Acad Sci. 1953 Jul 20;237(3):276–278. [PubMed] [Google Scholar]
  16. POLLOCK M. R. The activity and specificity of inducers of penicillinase production in Bacillus cereus, strain NRRL 569. Biochem J. 1957 Jul;66(3):419–428. doi: 10.1042/bj0660419. [DOI] [PMC free article] [PubMed] [Google Scholar]
  17. ROGERS H. J. Variant populations within a hyaluronidase-producing culture of Staphylococcus aureus. J Pathol Bacteriol. 1953 Oct;66(2):545–551. doi: 10.1002/path.1700660226. [DOI] [PubMed] [Google Scholar]
  18. ROLINSON G. N., STEVENS S., BATCHELOR F. R., WOOD J. C., CHAIN E. B. Bacteriological studies on a new penicillin-BRL. 1241. Lancet. 1960 Sep 10;2(7150):564–567. doi: 10.1016/s0140-6736(60)91642-1. [DOI] [PubMed] [Google Scholar]

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