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. 1962 Aug;84(2):394–406. doi: 10.1042/bj0840394

Effects of ouabain on cerebral metabolism and transport mechanisms in vitro

O Gonda 1, J H Quastel 1
PMCID: PMC1243682  PMID: 13900139

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. ACS G. Y., BALAZS R., STRAUB F. B. Adenozintrifoszfát szintézis agykéregszeletekben. Kiserl Orvostud. 1953 Nov;5(6):466–472. [PubMed] [Google Scholar]
  2. BELL J. L., MCILWAIN H., THOMAS J. The composition of isolated cerebral tissues; ascorbic acid and cozymase. Biochem J. 1956 Oct;64(2):332–335. doi: 10.1042/bj0640332. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. BIEBER L. L., BROOKES V. J., CHELDELIN V. H., NEWBURGH R. W. The isolation of a methylcholine containing phospholipid from Phormia regina larvae. Biochem Biophys Res Commun. 1961 Nov 29;6:237–240. doi: 10.1016/0006-291x(61)90369-2. [DOI] [PubMed] [Google Scholar]
  4. CRANE R. K., LIPMANN F. The effect of arsenate on aerobic phosphorylation. J Biol Chem. 1953 Mar;201(1):235–243. [PubMed] [Google Scholar]
  5. DUNHAM E. T., GLYNN I. M. Adenosinetriphosphatase activity and the active movements of alkali metal ions. J Physiol. 1961 Apr;156:274–293. doi: 10.1113/jphysiol.1961.sp006675. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. ELLIOTT K. A., PAPPIUS H. M. Factors affecting the potassium content of incubated brain slices. Can J Biochem Physiol. 1956 Sep;34(5):1053–1067. [PubMed] [Google Scholar]
  7. ELLIOTT K. A., VAN GELDER N. M. Occlusion and metabolism of gamma-aminobutyric acid by brain tissue. J Neurochem. 1958 Oct;3(1):28–40. doi: 10.1111/j.1471-4159.1958.tb12606.x. [DOI] [PubMed] [Google Scholar]
  8. ELLIOTT W. H. Studies on the enzymic synthesis of glutamine. Biochem J. 1951 Jun;49(1):106–112. doi: 10.1042/bj0490106. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. FURCHGOTT R. F., DE GUBAREFF T. The high energy phosphate content of cardiac muscle under various experimental conditions which alter contractile strength. J Pharmacol Exp Ther. 1958 Nov;124(3):203–218. [PubMed] [Google Scholar]
  10. GARDOS G. Potassium accumulation in guinea pig brain cortex slices. J Neurochem. 1960 Feb;5:199–201. doi: 10.1111/j.1471-4159.1960.tb13354.x. [DOI] [PubMed] [Google Scholar]
  11. GLYNN I. M. The action of cardiac glycosides on sodium and potassium movements in human red cells. J Physiol. 1957 Apr 3;136(1):148–173. doi: 10.1113/jphysiol.1957.sp005749. [DOI] [PMC free article] [PubMed] [Google Scholar]
  12. GORE M. B. R., MCILWAIN H. Effects of some inorganic salts on the metabolic response of sections of mammalian cerebral cortex to electrical stimulation. J Physiol. 1952 Aug;117(4):471–483. doi: 10.1113/jphysiol.1952.sp004761. [DOI] [PMC free article] [PubMed] [Google Scholar]
  13. GUROFF G., KING W., UNDENFRIEND S. The uptake of tyrosine by rat brain in vitro. J Biol Chem. 1961 Jun;236:1773–1777. [PubMed] [Google Scholar]
  14. HEALD P. J. Rapid changes in creatine phosphate level in cerebral cortex slices. Biochem J. 1954 Aug;57(4):673–679. [PMC free article] [PubMed] [Google Scholar]
  15. KAHN J. B., Jr, ACHESON G. H. Effects of cardiac glyosides and other lactones, and of certain other compounds, on cation transfer in human erythrocytes. J Pharmacol Exp Ther. 1955 Nov;115(3):305–318. [PubMed] [Google Scholar]
  16. KINI M. M., QUASTEL J. H. Carbohydrate--amino-acid inter-relations in brain cortex in vitro. Nature. 1959 Jul 25;184:252–256. doi: 10.1038/184252a0. [DOI] [PubMed] [Google Scholar]
  17. KRATZING C. C., NARAYANASWAMI A. The enzymic determination of energy-rich phosphates in brain. Biochem J. 1953 May;54(2):317–323. doi: 10.1042/bj0540317. [DOI] [PMC free article] [PubMed] [Google Scholar]
  18. KREBS H. A., EGGLESTON L. V., TERNER C. In vitro measurements of the turnover rate of potassium in brain and retina. Biochem J. 1951 May;48(5):530–537. doi: 10.1042/bj0480530. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. KUNZ H. A., SULSER F. Uber die Hemmung des aktiven Kationentransportes durch Herzglykoside. Experientia. 1957 Sep 15;13(9):365–367. doi: 10.1007/BF02179170. [DOI] [PubMed] [Google Scholar]
  20. LEE K. S., SCHWARTZ A., BURSTEIN R. An effect of cardiac glycosides on oxidative phosphorylation by heart mitochondria. J Pharmacol Exp Ther. 1960 Jun;129:123–127. [PubMed] [Google Scholar]
  21. MAIZELS M., REMINGTON M., TRUSCOE R. The effects of certain physical factors and of the cardiac glycosides on sodium transfer by mouse ascites tumour cells. J Physiol. 1958 Jan 23;140(1):61–79. doi: 10.1113/jphysiol.1958.sp005916. [DOI] [PMC free article] [PubMed] [Google Scholar]
  22. MCILWAIN H. Phosphates of brain during in vitro metabolism: effects of oxygen, glucose, glutamate, glutamine, and calcium and potassium salts. Biochem J. 1952 Oct;52(2):289–295. doi: 10.1042/bj0520289. [DOI] [PMC free article] [PubMed] [Google Scholar]
  23. MOORE S., STEIN W. H. Procedures for the chromatographic determination of amino acids on four per cent cross-linked sulfonated polystyrene resins. J Biol Chem. 1954 Dec;211(2):893–906. [PubMed] [Google Scholar]
  24. NARAYANASWAMI A. Creatine phosphokinase in mammalian brain. Biochem J. 1952 Oct;52(2):295–301. doi: 10.1042/bj0520295. [DOI] [PMC free article] [PubMed] [Google Scholar]
  25. POST R. L., MERRITT C. R., KINSOLVING C. R., ALBRIGHT C. D. Membrane adenosine triphosphatase as a participant in the active transport of sodium and potassium in the human erythrocyte. J Biol Chem. 1960 Jun;235:1796–1802. [PubMed] [Google Scholar]
  26. SCHANBERG S., GIARMAN N. J. Uptake of 5-hydroxytryptophan by rat brain. Biochim Biophys Acta. 1960 Jul 15;41:556–558. doi: 10.1016/0006-3002(60)90066-4. [DOI] [PubMed] [Google Scholar]
  27. SCHATZMANN H. J. Herzglykoside als Hemmstoffe für den aktiven Kalium- und Natriumtransport durch die Erythrocytenmembran. Helv Physiol Pharmacol Acta. 1953;11(4):346–354. [PubMed] [Google Scholar]
  28. SKOU J. C. The influence of some cations on an adenosine triphosphatase from peripheral nerves. Biochim Biophys Acta. 1957 Feb;23(2):394–401. doi: 10.1016/0006-3002(57)90343-8. [DOI] [PubMed] [Google Scholar]
  29. Stern J. R., Eggleston L. V., Hems R., Krebs H. A. Accumulation of glutamic acid in isolated brain tissue. Biochem J. 1949;44(4):410–418. [PMC free article] [PubMed] [Google Scholar]
  30. TAKAGAKI G., HIRANO S., NAGATA Y. Some observations on the effect of D-glutamate on the glucose metabolism and the accumulation of potassium ions in brain cortex slices. J Neurochem. 1959 Jun;4(2):124–134. doi: 10.1111/j.1471-4159.1959.tb13181.x. [DOI] [PubMed] [Google Scholar]
  31. TERNER C., EGGLESTON L. V., KREBS H. A. The role of glutamic acid in the transport of potassium in brain and retina. Biochem J. 1950 Aug;47(2):139–149. doi: 10.1042/bj0470139. [DOI] [PMC free article] [PubMed] [Google Scholar]
  32. TSUKADA Y., NAGATA Y., HIRANO S. Active transport of gamma-aminobutyric acid in brain cortex slices, with special reference to phosphorus-32 turnover of phospholipids in cytoplasmic particulates. Nature. 1960 May 7;186:474–475. doi: 10.1038/186474a0. [DOI] [PubMed] [Google Scholar]
  33. VARDANIS A., QUASTEL J. H. The effects of lead and tin organometallic compounds on the metabolism of rat brain cortex slices. Can J Biochem Physiol. 1961 Dec;39:1811–1827. doi: 10.1139/o61-202. [DOI] [PubMed] [Google Scholar]
  34. WEINER N., PERKINS M., SIDMAN R. L. Effect of reserpine on noradrenaline content of innervated and denervated brown adipose tissue of the rat. Nature. 1962 Jan 13;193:137–138. doi: 10.1038/193137a0. [DOI] [PubMed] [Google Scholar]
  35. WHITTAM R. Active cation transport as a pace-maker of respiration. Nature. 1961 Aug 5;191:603–604. doi: 10.1038/191603a0. [DOI] [PubMed] [Google Scholar]
  36. WOODMAN R. J., McILWAIN H. Glutamic acid, other amino acids and related compounds as substrates for cerebral tissues: their effects on tissue phosphates. Biochem J. 1961 Oct;81:83–93. doi: 10.1042/bj0810083. [DOI] [PMC free article] [PubMed] [Google Scholar]
  37. Weil-Malherbe H. Observations on tissue glycolysis. Biochem J. 1938 Dec;32(12):2257–2275. doi: 10.1042/bj0322257. [DOI] [PMC free article] [PubMed] [Google Scholar]
  38. Weil-Malherbe H. Studies on brain metabolism: The metabolism of glutamic acid in brain. Biochem J. 1936 Apr;30(4):665–676. doi: 10.1042/bj0300665. [DOI] [PMC free article] [PubMed] [Google Scholar]
  39. YOSHIDA H., NUKADA T., FUJISAWA H. Effect of ouabain on ion transport and metabolic turnover of phospholipid of brain slices. Biochim Biophys Acta. 1961 Apr 15;48:614–615. doi: 10.1016/0006-3002(61)90068-3. [DOI] [PubMed] [Google Scholar]

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