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. 2025 Aug 25;20(8):e0330420. doi: 10.1371/journal.pone.0330420

Integrated economic and sexual and reproductive health programming among married and unmarried adolescent girls in Nigeria: Results from a quasi-experimental cohort study

Mary Phillips 1,*, Roselyn Odeh 2, Meghan Cutherell 1, Abednego Musau 3, Claire W Rothschild 1, Albert Tele 4, Jenna Grzeslo 5, Alexis Coppola 1, Yusuf H Wada 2, Noel Tonka 2, Alhaji Alhassan Bulama 2, Kehinde Atoloye 6, Olusesan A Makinde 6
Editor: Ibrahim Jahun7
PMCID: PMC12440252  PMID: 40853909

Abstract

Adolescent girls in sub-Saharan Africa are disadvantaged in nearly every measure of well-being when compared to their male peers, resulting in worse health outcomes and lower economic activity. Economically empowering adolescent girls is one approach to improving girls’ wellbeing. Community-based groups that offer girls holistic support, such as increasing income generating capacity, fostering critical thinking, and building support for economic activity among their influencers, have been shown to improve economic and psychosocial assets. This paper describes the results of integrating economic empowerment programming into an existing sexual and reproductive health program for adolescent girls aged 15–19 in Kaduna and Ogun states in Nigeria. Outcomes of interest included increases in income generation and asset purchasing, improved decision-making around use of income and savings, and greater contribution to household expenditures as well as increases in contraceptive use and intention to use contraception in the future. The study was a quasi-experimental design consisting of an intervention group receiving the combined SRH and economic empowerment intervention and a concurrent comparison group receiving only the SRH intervention. Data was collected concurrently in both groups before participants were involved in the intervention (baseline) and nine months after (endline) for the same participants. Results varied by state, with exposure to the intervention associated with increases in the proportion of participants earning money (35pp increase in Kaduna, 58pp increase in Ogun) and almost equal increases in contributions to household expenses. Exposure to the intervention was associated with a significant increase in contraceptive use in Kaduna. Further, exposure to the intervention in Ogun was associated with significant increases in purchasing of assets and intent to use contraception in the future which were not observed in Kaduna. The findings suggest that layered economic empowerment programs can have positive outcomes for diverse cohorts of adolescent girls.

Introduction

Background

Adolescent girls in sub-Saharan Africa are disadvantaged in nearly every measure of well-being when compared to their male peers: girls are less likely to complete secondary school; more likely to be restricted in their movements; at higher risk for intimate partner violence; and experience lower perceptions of their own self-worth [1]. For instance, in Nigeria, more girls than boys drop out of junior and senior secondary school, 31% of girls are married prior to their 18th birthday while 37% have had a live birth before age 20 [24]. Higher rates of school dropout, and early marriage and childbearing occur in northern Nigeria than the national average. In Kaduna state, the median age at marriage is 16.6 years and age at first birth is under 19 years. In southern Nigeria, rates of child marriage and school dropouts are lower than in the north, but adolescent girls are at high risk for violence and face restrictions from negative gender and social norms. Consequently, more than 1 in 2 women in Ogun state have experienced physical violence [5]. School dropout and early marriage and childbearing contribute to higher fertility, worse health, and lower incomes [6]. Additionally, the children born to these women tend to experience low birth weight, lower rates of immunization, and higher risk of under-five mortality [79]. The consequences of harmful norms and practices, while dire for adolescent girls, are also detrimental to the communities and countries in which they live. Geographies where inequality is the greatest also experience the worst poverty and highest rates of conflict [10]. Gender inequalities limit women’s participation in the labor force, reducing potential economic gains. Investments that keep girls in school and equip them for entry into the workforce in equal numbers to men could add USD 7 trillion to the global economy [11].

One approach for addressing gender inequity is to economically empower women and girls [12]. Economic empowerment can be understood as a process ‘whereby women and girls experience transformation in power, agency, and economic advancement’ [12]. Economic empowerment should encompass individual-level efforts that improve incomes and systematic changes made in partnership with women and girls to improve their capacity to exercise their economic power in ways that matter to them [13,14]. Economic empowerment interventions for girls can be categorized by those that offer direct economic training and support, such as vocational training, financial education, or employment programs; combined programs that layer in additional components such as life skills or sexual and reproductive health (SRH) information to compliment the financial component; and community-based girls’ groups [15]. There is limited evidence on the effectiveness of vocational skills training specific to adolescents in low- and middle-income countries (LMICs). A systematic review conducted in 2017 established small positive effects of vocational and business training on employment, including formal employment. However, the effects increased when programs included a gender component, and increases in earnings were greater if the program included life skills or an internship [16].

Life skills are a set of competencies derived from skills, knowledge, and attitudes that allow young people to thrive [17] by improving their ability to navigate psycho-social challenges and increasing resilience [18]. Valuable life skills include decision-making, negotiation, and communication skills [1921]. Combining livelihood or vocational training with life skills is promising for increasing income, and contraceptive use [22]. Community-based girl groups (sometimes called safe spaces or girls’ clubs) constitute girl-only environments enhanced with supportive mentors aiming to build girls’ protective assets and improve outcomes in a range of domains [23]. Community-based girls’ groups from LMICs have been established to result in positive effects on individual-level outcomes such as improvements in attitudes and beliefs about gender and health, improvements in economic and psychosocial assets, and increases in knowledge and awareness. However, outcomes that depend on external factors, such as behavior and health status, show mixed effects, with inconsistent improvements in contraceptive uptake or reductions in child marriage [24]. Complementary programming that works with girls’ influencers to shift social norms is required to address the restrictions that preclude the attainment of intervention effects [24]. An example of such a program is the ENGINE program in Nigeria whose evaluation suggested that participation resulted in higher self-esteem, lower acceptance of violence, improved incomes, higher levels of engagement in income generating activities, and increased use of savings accounts, although results varied due to regional heterogeneity [25]. Despite the promising evidence, significant gaps exist in the understanding of what is effective, including the role of group dynamics on outcomes, the effect of savings on economic outcomes, differences in approaches for different cohorts of girls, and the optimal dosage of programming [24]. However, the current body of research suggests economic empowerment requires holistic investment in adolescent girls, with a focus on building their income generating capacity, as well as fostering critical thinking and building support for economic activity among their influencers.

In this paper we describe the results of integrating economic empowerment programming on top of an existing SRH program for adolescent girls aged 15–19 in two Nigerian states. We hypothesized that the combined intervention would lead to improvements in economic activity among girls, particularly increases in income generation and asset purchasing, improved decision-making around use of income and savings, and greater contribution to household expenditures as well as increase in the likelihood of contraceptive use and intention to use contraception in the future.

Materials and methods

Intervention background

This study was undertaken as part of the Adolescents 360 project, which aims to increase demand for, and voluntary use of modern contraception among adolescent girls aged 15–19 years [26]. The economic empowerment intervention was implemented between 2022–2023 in Kaduna in northern and Ogun in southern Nigeria. In each geography, girls in the intervention group participated in a four-session program designed to increase voluntary uptake of modern contraception and then a longer business skill development curriculum and vocational skills training. Participants in Kaduna were exclusively married girls while those in Ogun were primarily unmarried girls. Participants’ first contact with the program was through the SRH intervention. In southern Nigeria this included classes for girls focused on menstrual hygiene, pregnancy, sexual health and rights, negotiation skills, decision-making and goal setting. In northern Nigeria, the curriculum also included personal hygiene and sexual health as well as improving family nutrition, interpersonal skills, and effective communication. Both interventions offered girls one-on-one sessions with health providers to discuss individual contraceptive preferences and provision of contraceptive services for those who chose to take up a method. The economic empowerment intervention included five business upskilling group sessions of approximately 90 minutes each where girls identified their strengths, set goals for the future, and received basic business training. Girls then chose up to two vocational skills, one that was quick to master, such as soap-making, and one that required more time, such as tailoring or catering, to learn through an apprenticeship (Ogun) or through vocational training centers (Kaduna). Vocational training lasted four to five weeks depending on the skill selected. Girls opted to learn a variety of trades including catering, hair and make-up, poultry and fish farming, shoemaking and photography. During and after the vocational training, adolescent girls were provided with a mentor who offered support in developing and executing a business plan. The program culminated in a large, public graduation that doubled as a marketplace for adolescent girls to display products and services from their newly gained skills. Additional information on each program, including a comparison of what the standalone SRH intervention offered versus the layered economic empowerment intervention is described in Table 1.

Table 1. Program elements by geography.

Geography Northern Nigeria – SRH Northern Nigeria – SRH + EE Southern Nigeria – SRH Southern Nigeria – SRH + EE
Target Audience
Sub-Geography State: Kaduna State: Ogun
Marital Status Married Primarily unmarried
Target Age 15-19 15-19
Location Peri-urban/ Rural Urban
School Status Out-of-school/ In-school Out-of-school/ In-school
Program Dosage
Group Size (number of participants per session)
SRH Only; Economic Empowerment
12 12; 24 12 12; 20
Meeting Frequency 2x weekly 2x weekly 2x weekly 2x weekly
Session Duration 90 minutes 90 minutes 90 minutes 90 minutes
Program Duration 2 weeks 12 weeks 2 weeks 12 weeks
Program Elements
Life Skills Yes Yes No Yes
Mentorship/ Coaching No Yes No Yes
Social/ Girls’ Group Yes Yes No Yes
Influencer outreach Yes Yes Yes Yes
Vocational Training Yesa Yes No Yes
Business Training No Yes No Yes
Financial Education No Yes No Yes
Savings No Yes No Yes
Linkage to Markets No Yes No Yes
SRH knowledge (contraception) Yes Yes Yes Yes
SRH access (contraception) Yes Yes Yes Yes

a Light-touch approach of one 90-minute sessions on quick-to-learn skills such as beading and soap-making.

Research design

This study was conducted from June 2022 to April 2023. We employed a quasi-experimental design consisting of an intervention and a concurrent comparison group. For the intervention group, participants were adolescent girls aged 15–19 who received the combined SRH and economic empowerment intervention. A similarly sized cohort of adolescent girls of the same age group who only received an SRH intervention constituted the comparison group. Data was collected concurrently in both groups before participants were involved in the intervention (baseline) and nine months after (endline) for the same participants. Intervention clusters were the same locations where the intervention design was being implemented while comparison clusters were conveniently selected from the same state for easy accessibility by the research team but geographically distant from the intervention clusters to reduce spillover effects.

Participants and sampling

Recruitment.

Study participants were recruited by female program mobilizers promoting the SRH intervention using recruitment scripts. In Ogun, recruitment took place from May 24, 2022, to June 30, 2022. In Kaduna, recruitment took place from May 23, 2022, to June 30, 2022. Recruitment could take place in participants’ homes, community or public spaces, or at the health facility. The female mobilizers originated from the communities where the SRH intervention was ongoing and were familiar with households where adolescents aged 15–19 years lived. At the initial contact with the adolescent girls, mobilisers requested to speak to them in private and administered the screening questions, which were built on the recruitment scripts. The inclusion criteria required that all participants be adolescent girls between the ages of 15–19, living in the selected study areas, willing to participate in the baseline and endline assessments, and with no plan to migrate out during the study period. Participants in northern Nigeria had to be married or living as if married to participate. An additional criteria for the intervention group was a willingness to participate in a three-month intervention, although specific details of the program content were not shared. During the recruitment, girls who were eligible but declined to participate in the study were still able to participate in the intervention activities. Eligible adolescent girls who expressed interest to participate in the study provided their phone contact details or physical addresses which were recorded in a confidential recruitment sheet and relayed to a trained female data collector. Female data collectors then contacted the individuals and scheduled an in-person meeting at the study site. Potential participants were informed by interviewers about the study objectives, time commitment, confidentiality, and any potential risks that could result from the study before they were asked to provide their consent to participate. Recruitment was continuous until the sample size was attained. The estimated sample size in each geography was 400 participants for each group which had been projected to be adequate to detect a modest average treatment effect of 10% difference-in-the-difference in the primary outcome variable (currently earning money) across the study groups between the two time points assuming 50% of participants in both groups were earning money at baseline at the 95% confidence level with 80% power. The sample was adjusted upwards to account for a 10% attrition rate for each group.

Data collection.

The same structured questionnaire was used at baseline and endline. At endline, additional questions were included to document participants’ exposure to economic empowerment programming. Trained female data collectors and supervisors were deployed to manage the field data collection. Data was collected using the Computer Assisted Personal Interview (CAPI) approach using the offline android application of the Open Data Kit (ODK) platform. All survey tools were translated from English into local languages (Hausa and Yoruba) and back-translated to ensure accuracy. Surveys were pre-tested with program participants in non-survey areas before data collection commenced to screen for survey programming errors and verify quality of data collectors. Scheduling for the endline surveys were conducted through phone calls or physical tracing through the female mobilisers who had recruited the participants. Interviews were conducted in-person except for Ogun where phone surveys were conducted in an attempt to reduce the attrition rates. Participants also received an incentive worth two US dollars in Nigeria naira after successfully completing the endline survey.

Measures

The study examined outcomes in two domains – economic and SRH – which were measured at baseline and repeated at endline using the same questions. Both domains were measured through self-reported responses in the survey questionnaires.

  • Economic domain measures: The three measures for this domain were earning money (the study primary outcome), purchasing assets and contributing to household expenses. For earning money, all participants were asked ‘Do you earn money?’, with possible close-coded responses of ‘Yes’, ‘No’, and ‘Don’t know.’ For purchasing assets, all respondents were given a list of nine assets, asked if they purchased each one and, if so, to respond with ‘Yes’ or ‘No’ to whether they used their own money to purchase the asset. Additionally, interviewers asked ‘Have you used your own money to purchase an item that I did not list?. To measure how frequently girls contributed to their household expenditure, participants were asked, ‘In the last three months, how often did you contribute to household expenses? Possible responses included, ‘never, rarely, monthly, or weekly’. We created a dichotomous variable on contribution to household expenses, in which we coded weekly, monthly, and rarely responses as 1 (yes) while never, refused, and don’t know responses were coded as 0 (no).

  • SRH domain measures: The two measures for this domain were current contraceptive use and intent to use contraceptive in the future. To measure current contraceptive use, a slightly different approach was used for participants in Kaduna and Ogun. In Kaduna, since all participants were married, we assumed they had a potential need for modern contraception. To better understand the contraceptive needs of the participants in Ogun where girls were predominantly not married, we asked: ‘Have you ever had sex?’. All respondents in Kaduna and respondents from Ogun who had ever had sex were asked, ‘Are you or your partner currently using any method to avoid pregnancy?’ To assess intention to use contraceptives in the future, current non-users of contraception irrespective of sexual activity were asked, ‘Do you intend to use any method to avoid pregnancy in the next year?’. Those who responded with a “No” were then asked, ‘Do you intend to use any method to avoid pregnancy in the future?’. A binary outcome referred to as intent to use contraception any time in the future was computed from the responses to these two questions for all current non-users.

In addition to the measures in the two domains, at endline, intervention group participants were asked six questions about their participation in the different intervention components. For components that took place over multiple sessions, responses were gathered on whether participants participated in none, some, or all sessions or replied with the specific number of sessions attended. For the comparison group, participants were asked, ‘In the last nine months, have you participated in a program to help you reach your economic goals such as an apprenticeship program, vocational training, etc.?’ and the name of the program. For the specific questions asked, see S1 File.

Ethical considerations

Approval for this study was received from the National Health Research Ethics Committee of Nigeria (Approval Number: NHREC/01/01/2007-06/05/2023B) and the Population Services International Research Ethics Board (09.2022). All participants 18 years and older and emancipated minors under 18 (married adolescents) provided written informed consent. Unmarried minors provided written informed assent in lieu of consent (southern Nigeria only).

Data confidentiality and security

Password protected electronic devices were employed to capture survey responses using CAPI. Survey records were submitted to a secure institutional server daily or immediately if internet connection was available. Data was encrypted during transmission and the server was only accessible to authorized members of the research team.

Inclusivity in global research

Additional information regarding the ethical, cultural, and scientific considerations specific to inclusivity in global research is included in the supporting information (S2 File).

Statistical analyses

We used frequencies to describe participants’ background characteristics and program dosage. Chi-square tests were conducted to identify variables where there were statistically significant differences between the intervention and comparison groups at baseline. Generalized Estimating Equation (GEE) models were fitted for the binary outcomes using the gaussian family distribution and identity link function, employing an exchangeable covariance structure using robust standard errors. Linear models, also referred as linear probability models, can be used to assess absolute, rather than relative, changes in binary outcomes, providing valid inference with the use of robust standard errors even with known misspecification of the outcome distribution [27]. The GEE model included independent variables for study group (coded as a binary variable equal to 0 for the comparison group and 1 for the intervention group), time (coded as 0 for baseline and 1 for endline) and a group-time interaction term as the difference-in-differences (DiD) estimator. Model based estimates of the changes from baseline, standard errors (SE) and corresponding 95% confidence intervals (CIs) are provided along with p-values for documenting statistical significance. See S1 Table for the full model. We report results from the adjusted models that include covariates for baseline measures parameterized as follows: age (15–17 = 0; 18–19 = 1), education level (no formal school = 0; primary = 1; secondary = 3; above secondary = 3), marital status (not married = 0; married = 1) and parity (none = 0; 1 = 1 and 2 or more = 2) as categorical variables. The selection of the covariates was informed by literature on the factors that influence economic capabilities as well as variables that showed group differences at the baseline survey. Results of the analysis of the adjusted vs. unadjusted DiD are summarized in S2 Table.

Results

Sample characteristics

In Kaduna, 1,052 girls were mobilized to participate in the study (559 for the intervention group and 493 for the comparison group). Among these 1,049 (556 intervention, 492 comparison) were enrolled and surveyed at baseline, with three participants deemed ineligible in the intervention cohort due to being outside the target age range. At endline, 841 were interviewed (474 intervention, 367 comparison) resulting in follow-up rates of 85.3% and 74.4%, respectively. In Ogun, 927 girls were recruited (501 for the intervention group and 426 for the comparison group) and all enrolled and surveyed at baseline. At endline, 664 were interviewed (406 intervention, 258 comparison) resulting in follow-up rates of 81.0% and 60.6%, respectively. See Fig 1.

Fig 1. Study flow diagrams for Kaduna and Ogun states.

Fig 1

Table 2 shows the participant characteristics between intervention and control groups within geographies. In Kaduna, girls in the intervention group were significantly older than those in the comparison group, while in Ogun, girls in the intervention group were significantly younger. School-going rates and school achievement were high in both Nigerian geographies, although girls in the comparison group in Kaduna were significantly more likely to have no education than those in the intervention group. As designed, in Kaduna, all participants were married and in Ogun most participants were unmarried. Child-bearing rates followed the trend in marital status. Notable differences were observed within the geographies for parity, with the intervention group being significantly more likely to have given birth than the comparison group in Kaduna, but less likely in Ogun.

Table 2. Participant socio-demographic characteristics for the intervention and comparison groups by geography.

Characteristic (at endline) Ogun p-value Kaduna p-value
Intervention Control Intervention Control
n (%) n (%) n (%) n (%)
Age
Age 15–17 222 (54.7%) 112 (43.4%) 0.005 29 (6.1%) 59 (16.1%) <0.001
Age 18–19 184 (45.3%) 146 (56.6%) 445 (93.9%) 308 (83.9%)
School Status
Out-of-school 248 (61.4%) 159 (61.6%) 0.950 128 (27.2%) 119 (34.5%) 0.026
Highest Level of Education
No formal education 1 (0.2%) 0 (0.0%) 0.838 11 (2.3%) 91 (24.8%) <0.001
Primary 12 (3.0%) 7 (2.7%) 9 (1.9%) 57 (15.5%)
Secondary 367 (90.6%) 237(91.9%) 368 (77.6%) 193 (52.6%)
Above Secondary 25 (6.2%) 14 (5.4%) 86 (18.1%) 26 (7.1%)
Married/ Living as Married
Yes 17 (4.2%) 21 (8.2%) 0.032 474 (100.0%) 367 (100.0%) n/a
Parity
0 308 (75.9%) 159 (61.6%) <0.001 32 (6.8%) 52 (14.2%) <0.001
1 31 (7.6%) 32 (12.4%) 206 (43.5%) 92 (25.1%)
≥2 67 (16.5%) 67 (26.0%) 236 (49.8%) 223 (60.8%)

Analysis of differential attrition

We conducted additional analysis to understand if there were significant differences on the primary outcomes at baseline between participants lost to follow-up (LTFU) and those who were not. In Kaduna, there were no significant differences across all outcomes. However, in Ogun there were significant differences between participants LTFU and those who were not in purchasing assets (p = .013) and earning money (p < .001) in the intervention group. Participants LTFU had higher rates of purchasing assets than those who were not (70.5% vs. 57.1%) and for earning money (42.1% vs. 19.5%). Baseline values for these two variables were incorporated as covariates in the adjusted DiD models, if they did not serve as an outcome variable. The full results of the differential analysis are presented in S3 Table.

Program exposure

Overall, self-reported attendance across all key elements of the intervention was over 90% for participants in the intervention groups (see Table 3). A quarter of girls in the comparison group (28.3%) in Ogun reported that they had participated in any economic empowerment activity. Rates were higher in the Kaduna comparison group, where over half (59.1%) reported participating in some sort of economic empowerment activity (see Table 3). In Kaduna, 174 (80.1%) of among the 217 girls participating in an apprenticeship program reported that the source was A360’s SRH program, which contains low-dosage skills training.

Table 3. Exposure to intervention activities among intervention group and any economic empowerment intervention among comparison group at endline.

Intervention Group Ogun Kaduna
Participated in the life mapping/ goal setting Yes 398 (98.0%) 466 (98.3%)
Participated in the primary package sessions (SRH) All sessions 350 (86.2%) 431 (90.9%)
Participated in secondary package sessions (ES skills) All sessions 369 (90.9%) 437 (92.2%)
Participated in vocational skills sessions Yes 397 (97.8%) 463 (97.7%)
Number of one-on-one coaching sessions attended None 0 6 (1.3%)
1-2 287 (70.7%) 133 (28.1%)
>2 94 (23.2%) 303 (63.9%)
Refused 25 (5.2%) 32 (6.8%)
Number of group coaching sessions attended 1-2 198 (48.8%) 37 (7.8%)
>2 187 (46.1%) 434 (91.6%)
Refused 21 (5.2%) 3 (0.6%)
Comparison Group
Participated in an apprenticeship program, vocational training, etc., in the last nine months Yes 73 (28.3%) 217 (59.1%)

Economic outcomes

Earns money.

In both geographies, the intervention group was significantly more likely to report earning money at endline than the comparison group as depicted in Figs 2 and 3. In Kaduna, exposure to the program was associated with a 35pp greater likelihood of self-reported earning money (95% CI [0.28; 0.43], p < 0.001). Table 4 illustrates results for the three economic outcomes in both geographies. In Ogun, exposure to the program was associated with 58pp greater likelihood of self-reported earning money (95% CI [0.50; 0.67], p < 0.001).

Fig 2. Baseline and endline economic and SRH outcomes in Kaduna.

Fig 2

Fig 3. Baseline and endline economic and SRH outcomes in Ogun.

Fig 3

Table 4. Adjusted difference-in-difference estimates for economic outcomes.
Kaduna Ogun
Baseline Endline Diff Baseline Endline Diff
Earns Money Earns Money
Baseline: Intervention: (n = 556) Comparison (n = 493) Baseline: Intervention: (n = 406) Comparison (n = 258)
Endline: Intervention: (n = 474) Comparison (n = 367) Endline: Intervention: (n = 405) Comparison (n = 255)
Comparison 60.85 70.57 9.72 Comparison 24.81 45.1 20.29
Intervention 53.6 99.37 45.77 Intervention 19.46 95.06 75.6
Adjusted DiD 0.35(0.28; 0.43) p < 0.001 Adjusted DiD 0.58 (0.50; 0.67)*** p < 0.001
Purchases Assets Purchases Assets
Baseline: Intervention: (n = 554) Comparison (n = 493) Baseline: Intervention: (n = 405) Comparison (n = 258)
Endline: Intervention: (n = 474) Comparison (n = 367) Endline: Intervention: (n = 406) Comparison (n = 258)
Comparison 76.06 87.19 11.13 Comparison 82.56 95.35 12.79
Intervention 72.56 91.14 18.58 Intervention 57.28 97.54 40.26
Adjusted DiD 0.06(−0.01; 0.13) p = 0.103 Adjusted DiD 0.31 (0.23; 0.38)*** p < 0.001
Contributes to household expenses Contributes to household expenses
Baseline: Intervention: (n = 298) Comparison (n = 300) Baseline: Intervention: (n = 79) Comparison (n = 64)
Endline: Intervention: (n = 472) Comparison (n = 297) Endline: Intervention: (n = 402) Comparison (n = 187)
Comparison 79 73.74 −5.26 Comparison 48.44 17.65 −30.79
Intervention 58.72 71.82 13.1 Intervention 36.71 29.6 −7.11
Adjusted DiD 0.29(0.21; 0.36)*** p < 0.001 Adjusted DiD 0.28 (0.11; 0.45)** p = 0.002

Purchases assets.

In Kaduna, exposure to the intervention was not associated with a significant change in the proportion of adolescent girls who reported purchasing at least one asset with their own money in the preceding 12 months. Exposure to the program was associated with a non-significant 6pp increase in reporting the purchase of an asset (95% CI [−0.01; 0.13], p = 0.103). In Ogun, exposure to the intervention was associated with a significant change in the proportion of participants reporting the purchase of an asset in the twelve months preceding the survey. Exposure was associated with a 31pp increase in reporting the purchase of an asset (95% CI [0.23; 0.38], p < 0.001).

As a secondary outcome, we tracked the specific assets purchased to understand the types of items participants were spending their money on. In Kaduna at endline, a greater share of the intervention group had purchased livestock, kitchen utensils and home furniture than in the comparison group. At endline more participants in the comparison group reported the purchase of wrappers (hollandis) than those in the intervention group. Purchasing patterns were different in Ogun, where more participants in the intervention group reported purchases of phones, watches, and work tools at endline than in the comparison group. At endline more participants in the comparison group reported purchase of jewelry compared to the intervention group (results not shown).

Contributes to household expenses.

In Kaduna, the intervention was associated with a statistically significant increase in contributing to household expenses probably due to decreases in contributions in the comparison group. Exposure to the program was associated with a 29pp greater likelihood of self-reported contribution to household expenses (95% CI [0.21; 0.36], p < 0.001). Since this outcome included only participants who were earning money, it’s worthwhile to consider the overall shifts in the total number of participants contributing to household expenses, as well as the proportions. Among the comparison group, 276 participants were contributing to household expenses at baseline and 271 were contributing at endline. Among the intervention group, 266 participants were contributing at baseline and 454 were contributing at endline. In Ogun, exposure to the intervention was associated with a statistically significant increase in contribution to household expenses. There was a decline in the percentage of participants contributing to household expenses at endline, but the drop was relatively moderate in the intervention group. Exposure to the program was associated with a 28pp greater likelihood of contribution to household expenses among those earning money (95% CI [0.11; 0.45], p = 0.002). In Ogun, there was a notable increase in the proportion of overall participants contributing to household expenses at endline in the intervention group. At baseline 31 participants from the comparison group reported contributing to household expenses, compared to 33 at endline, 12.0% and 12.9% of all comparison group participants, respectively. Among the intervention group 29 participants reported contributing to household expenses at baseline and 119 reported contributing at endline, 7.1% and 29.4% of all intervention group participants, respectively.

Reproductive health outcomes

Sexual activity in Ogun.

In Ogun at baseline, about half of participants (49.8%) in the comparison group had ever had sex. At endline, this increased to 65.1%. Sexual activity rates were lower in the intervention group. Only 23.2% of participants reported ever having sex at baseline and this percentage increased only marginally at endline to 26.8%.

Modern contraceptive use.

In Ogun at baseline, among participants who had ever had sex, 80.2% in the comparison group and 63.5% in the intervention group reported currently using a method of contraception. In both groups, current contraceptive use dropped at endline although the decline was less dramatic in the intervention group. At endline, current contraceptive use among participants who had ever had sex was 48.5% in the comparison group and 50.5% in the intervention group. Exposure to the program was associated with a non-significant 17.9pp (95% CI [−0.01; 0.37], p = 0.060) greater likelihood of current contraceptive use among participants who had ever had sex. In Kaduna at baseline 39.7% of participants in the comparison group and 35.9% of participants in the intervention group reported currently using contraception. At endline, 55.4% of participants in the comparison group and 84.9% of participants in the intervention group reported current contraceptive use. Exposure to the program was associated with a 207pp increase in contraception use (95% CI [0.67; 3.48], p = 0.004).

Intent to use modern contraception.

In Kaduna at baseline 55.4% and 84.9% of participants not currently using a contraceptive method in the comparison and intervention groups, respectively, reported an intent to use contraception in the future. At endline, 60.5% and 87.5% of participants not currently using a method in the comparison groups and intervention groups, respectively, reported the same. Exposure to the program was not associated with an increase in intent to use contraception. In Ogun at baseline, 36.0% of participants in the comparison group and 50.5% of participants in the intervention group not currently using contraception reported an intent to use contraception in the future. At endline, these figures increased so that 41.0% of current non-users in the comparison group and 73.9% of current non-users in the intervention group were intending to use contraception in the future. Exposure to the program was associated with a 48pp increase in intent to use contraception in the future among current non-users (95% CI [0.21; 0.75], p = 0.001).

For all reproductive health outcomes, see Table 5.

Table 5. Adjusted difference-in-difference estimates for SRH outcomes.
Kaduna Ogun
Baseline Endline Diff Baseline Endline Diff
Contraceptive use Contraceptive use
Baseline: Intervention: (n = 543); Comparison (n = 484) Baseline: Intervention: (n = 74); Comparison (n = 121)
Endline: Intervention: (n = 474); Comparison (n = 366) Endline: Intervention: (n = 109); Comparison (n = 167)
Comparison 39.67 52.73 13.06 Comparison 80.17 48.5 −31.67
Intervention 35.91 89.87 53.96 Intervention 63.51 50.46 −13.05
Adjusted DiD 2.07(0.67; 3.48) p = 0.004 Adjusted DiD 0.18 (−0.01; 0.37) p = 0.600
Intends to use contraception Intends to use contraception
Baseline: Intervention: (n = 344); Comparison (n = 280) Baseline: Intervention: (n = 356); Comparison (n = 111)
Endline: Intervention: (n = 48); Comparison (n = 172) Endline: Intervention: (n = 351); Comparison (n = 173)
Comparison 55.36 60.47 5.11 Comparison 36.04 41.04 5
Intervention 84.88 87.5 2.62 Intervention 23.88 72.93 49.05
Adjusted DiD 0.00(−0.14; 0.14) p = 0.891 Adjusted DiD 0.48 (0.21; 0.75) p = 0.001

Discussion

The findings suggest that the layered economic empowerment intervention led to statistically significant, positive outcomes for adolescent girls in both geographies. Results were especially pronounced for the outcome on earning money in both Kaduna and Ogun. Our findings align with previous assessments on the potential to improve earnings through interventions that promote financial education or vocational and/or business skills interventions [22,28]. While earning is an important first step on the pathway to economic empowerment, it is necessary to understand how this money is being used and resulting changes in behavior or power at the household and community level. In Kaduna, exposure to the intervention had no effect on purchasing assets, while in Ogun exposure led to a 31pp increase in purchasing assets. Although there was no significant effect in Kaduna, over 90% of girls in the intervention group had purchased an asset in the 12 months preceding endline. The intervention effect detected in Ogun was attributable to a larger change in the intervention group of the proportion of girls who had purchased an asset between baseline and endline. Notably, the intervention group in Ogun constituted relatively younger girls who might not have had opportunities to purchase assets prior to the intervention because of weak economic capabilities. Interestingly, program participation was associated with higher likelihood of buying assets that support income generating activities – such as livestock in Kaduna and “work tools” in Ogun. These findings suggest a cycle of economic empowerment, in which early earnings are successfully invested in growing the income generating activity. This use of income is encouraging, given previous research that suggests women often face more pressure to spend money on urgent family needs, leaving less for investments in business growth [29]. The authors speculate that the work done on goal setting and sharing goals with key influencers (husbands and parents) may have given girls the tools (persuasion, planning, and confidence) required to negotiate use of their earnings.

In both geographies, exposure to the intervention was associated with increased contributions to household expenses. For girls and young women, contributing to household expenditure may be an important way to gain status and reduce instances of interpersonal violence [30]. The proportion of girls contributing to household expenses in the previous three months in both the intervention and comparison groups was much higher in Kaduna than in Ogun, which probably reflects their status as married women who have a responsibility to contribute to overall household well-being versus unmarried girls who may face fewer obligations to support the household. In Ogun contributions dropped from baseline to endline in both the comparison and intervention group, but the magnitude of the change was much smaller in the intervention group, resulting in a positive estimate of program impact. This may suggest that the intervention offered some protective properties that enabled girls to keep contributing to their household, despite external factors that made it harder to do so. For instance, economic contributions among unmarried girls may have been affected by the restart of the school year and limited opportunities to engage in income generation.

Findings on SRH outcomes are mixed, which aligns with findings from other multi-component programs [31]. In this study, all participants (intervention and comparison) received the SRH intervention and so the study was designed to measure the incremental effect of layering on the economic empowerment component. The clearest benefits were in Kaduna, where exposure to the intervention was associated with a 200pp increase in self-reported contraception use, and nearly 90% of intervention group respondents reported using a method of contraception at endline. Kaduna state, in general, has low rates of contraceptive use among married adolescents and high birth rates [5]. These results show the potential of combined economic and health programming that helps girls understand the connection between health seeking behaviors (in this case contraceptive uptake) in pursuit of larger life goals, such as income generation. In Ogun, exposure to the program was not associated with increases in contraceptive use among sexually active girls. For many girls in the south, contraceptive use may not be a relevant practice: only 1 in 4 girls in the intervention group and 1 in 2 girls in the comparison group reported they had ever had sex at endline. Given that we did not capture information on frequency and recency of sexual activity, our measurement approach may overestimate the proportion of girls who are at risk of pregnancy. As has been discussed extensively elsewhere, contraceptive uptake among unmarried girls, who often have infrequent, covert sex is a challenge for public health programming [32]. Furthermore, evidence suggests that younger and unmarried girls are less likely to benefit from the SRH components for combined interventions because of a limited understanding of sexuality and reproduction but also because session facilitators might face personal discomfort and technical difficulties covering SRH content [28]. There is a need to support girls who have intermittent sex and therefore inconsistent need for contraception in a way that is in line with their preferences and to develop metrics that better respond to patterns of intermittent need. In Kaduna, there was no associated effect of program exposure on intent to use contraception, as intent to use stayed relatively high (over 85%) among the intervention group between baseline and endline. In Ogun, however, exposure to the program resulted in a 48pp increase in reported intent to use contraception. The integrated intervention provided girls additional contact with mentors to learn more about SRH, to discuss their concerns and to receive positive reinforcement about the role of contraception as a tool for pursuing their self-defined goals, motivating their willingness to use contraception in the future. Contrastingly, for the girls from Kaduna who were married contraception was relevant and those who desired to use contraception might already have adopted a method leaving only those pursuing motherhood to respond to this question. While intent does not guarantee future contraceptive use, it is a promising signal that girls in the combined program model see the relevance of contraception for attaining their goals and may be primed to choose to take up a method in the future when they do determine that they are in need.

There are several limitations that should be considered when interpreting the results of this study. First, because allocation of intervention sites had already been determined at the time of study design, we used a quasi-experimental, non-randomized evaluation design. Further, the use of program mobilizers for participant recruitment could have introduced a selection bias specifically for adolescent girls joining the intervention group. For instance, mobilisers could have preferred to recruit relatives, daughters of their friends or girls of specific religious, ethnic or clan affiliations. To mitigate the effects of this bias, we examined group differences using baseline data and employed any demographic variables where there was a difference as covariates in our DiD analysis. While our DiD approach accounts for time-invariant confounding (both measured and unmeasured), there is a possibility of unmeasured confounding by time-varying factors differentially impacting the intervention and comparison groups. In our study there were only nine months between the baseline and endline studies, which is a short period of time to show the sustainability of the observed changes in economic empowerment and SRH outcomes. A longer time period may have allowed us to show stronger intervention effects or provided more confidence about the long-term durability of the effects seen initially. The attrition at endline, especially in Ogun state, may have biased our final results towards girls who had more need for the program and were therefore faster to show initial results. We addressed this limitation by including baseline values of the factors that showed significant differences between the intervention and comparison groups and those retained and LTFU in our analysis.

Conclusion

Our findings provide relevant insights to guide economic empowerment programming that addresses the needs of different girls in diverse settings. While the study populations were drawn from the same age cohort and country they represent important differences within sub-populations of adolescent girls. A key contribution of this study is its inclusion of diverse sub-groups of adolescent girls – a population that is often, inaccurately, considered to be homogenous across sub-Saharan Africa. The study assessed program effectiveness among married and unmarried girls, differing levels of education attainment, urban and rural, with children and without, and in different cultural contexts. What is notable is the consistency of positive impacts in the key dimensions measured, despite these differences. As discussed above, given their differences in marital status, the social role placed on the girls in Kaduna and the girls in Ogun is likely quite different. In Kaduna, married girls may be viewed socially as women, with responsibility to care for their children and home. They are also greatly constrained by gender norms and lack the freedom to leave the home or seek work without permission from their husbands. The program addressed this barrier by engaging with community leaders who showed support of the girls’ economic activities and provided an enabling environment for their participation in income generation. Given their status as adults with responsibility, once there was general social approval, girls were highly motivated to contribute to their own households. In Ogun, by contrast, unmarried girls are likely still viewed as children, with limited capacity to contribute economically and under the restrictions of their parents. Again, by working with key influencers in the community the program was able to generate support for these girls and help shift perspectives about their social role. Many girls in Ogun chose to contribute their money earned to school expenses, a goal supported by unmarried girls’ influencers. Understanding the specific barriers in place for girls in each context and incorporating thoughtful program elements to address those barriers can mean the difference between success and failure.

Supporting information

S1 File. Program exposure questions.

(DOCX)

pone.0330420.s001.docx (29.3KB, docx)
S1 Table. GEE model.

(XLSX)

pone.0330420.s002.xlsx (18.2KB, xlsx)
S2 Table. Comparison of unadjusted and adjusted DiD.

(DOCX)

pone.0330420.s003.docx (22.5KB, docx)
S3 Table. Differential attrition analysis table.

(DOCX)

pone.0330420.s004.docx (28.4KB, docx)
S2 File. Questionnaire on inclusivity in global research.

(DOCX)

pone.0330420.s005.docx (74.4KB, docx)

Acknowledgments

The authors are grateful to the staff of the Royal Heritage Health Foundation (RHHF) and Society for Women Development and Empowerment in Nigeria (SWODEN) who were implementation partners for this program. We acknowledge the contributions of the members of the Society for Family Health Nigeria who oversaw delivery of this program and the contributions of the Nigerian-based research team Viable Knowledge Masters. We acknowledge the adolescent girls who took the time to participate in the survey and appreciate their willingness to contribute to this work.

Data Availability

The data supporting the findings in this study are publicly available in Figshare under a CC BY 4.0 license under the title “A360 Economic Strengthening Pilot Evaluation Dat Sets” and DOI: https://doi.org/10.6084/m9.figshare.29390573.v1.

Funding Statement

Individual authors did not receive specific awards. This work was supported by the Bill & Melinda Gates Foundation (https://www.gatesfoundation.org/) INV-004274 and the Children’s Investment Fund Foundation (https://ciff.org/) R-1911-04245. Awards were given to Population Services International to support the overall program design, operations, and study. The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.

References

Decision Letter 0

Ibrahim Jahun

3 Dec 2024

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  • This section is too long. Even though no word limit provided in author’s guide, there is need to be concise and direct to the points relating to the objectives of the paper. The section now spans to about 5 pages and will be better if the section is concisely reduced to 2.5 pages. This will enable readers not to be lost regarding the study objectives.

  • The section will also benefit from basic statistics about reproductive health indicators among young girls globally and in Nigeria as well as statistics about poverty in this population (when compared to young men counterparts). The section should read like a scientific paper with facts (data) and not like a book.

Methods:

  • Recruitment: It is confusing how 400 participants relate to Table 1, whereby 12 groups and 24 upskills were reported. Please make this clearer or reconcile.

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  • Please split the section into “Discussion” and “Conclusion and Recommendation”.

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Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

Reviewer #1: Yes

Reviewer #2: Partly

**********

2. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #1: Yes

Reviewer #2: Yes

**********

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Reviewer #1: Yes

Reviewer #2: Yes

**********

Reviewer #1: The study addresses an important gap by examining the effects of integrated economic empowerment and sexual and reproductive health (SRH) interventions on adolescent girls in Nigeria. This is particularly valuable given the unique challenges faced by this demographic.

However there are some improvements I would recommend:

1. Abstract Clarity: The abstract is dense, especially in terms of results. It would be beneficial to streamline the findings to highlight the most impactful outcomes.

2. Introduction - Background Context: The background is comprehensive but could benefit from a more focused framing of the economic and SRH challenges specifically faced by adolescent girls in Nigeria. Additionally, contextualizing this intervention in the broader scope of Sub-Saharan Africa would help readers unfamiliar with the region.

3. Methodological Details:

• Sampling and Recruitment: More details about the sampling process, including any potential biases, would enhance the transparency and replicability of the study.

• Covariates and Confounding: The manuscript mentions adjustments for certain covariates. It would be helpful to clarify why specific variables (e.g., age, education) were chosen and to justify their relevance in the analysis.

4. Discussion and Implications:

• Interpretation of Findings: The discussion could benefit from more critical reflection on why certain outcomes varied significantly between Kaduna and Ogun, particularly regarding SRH outcomes. Exploring cultural, social, or structural factors could provide readers with a more nuanced understanding.

• Program Duration and Sustainability: The study was conducted over a nine-month period, which limits long-term outcome assessment. Discussing the sustainability of these outcomes beyond the study period would be valuable.

5. Typographical Errors: A thorough proofreading would help eliminate minor typographical errors and improve readability.

Reviewer #2: 1. Expand the Timeline

• The study observed changes over nine months, which might not fully capture the long-term effects of the intervention. Extending the study period would provide more robust insights into sustained outcomes, particularly in economic empowerment and contraceptive use.

2. Address Attrition Issues

• Attrition rates were high, especially in Ogun. Future studies could employ strategies such as incentivizing participation, increasing community engagement, or using mobile follow-ups to reduce loss to follow-up and ensure a more representative sample at endline.

3. Enhance Measurement of SRH Outcomes

• Include detailed questions on sexual activity (e.g., frequency and recency) to better estimate contraceptive needs among participants. Additionally, qualitative methods like focus group discussions could uncover deeper reasons for changes in SRH behaviors.

4. Explore Regional Variability

• The study noted significant differences in outcomes between Kaduna and Ogun. Future research should delve into the contextual factors, such as cultural norms and economic conditions, to tailor interventions more effectively for each region.

5. Incorporate Broader Indicators of Empowerment

• While economic empowerment was assessed through earnings, asset purchases, and contributions to household expenses, consider adding measures like financial independence, agency in decision-making, and changes in social norms as broader indicators.

6. Strengthen Comparisons

• In non-randomized designs, controlling for potential confounding variables is critical. Future studies could implement propensity score matching or more sophisticated econometric techniques to reduce bias in comparisons between intervention and control groups.

7. Consider Mixed Methods

• Quantitative surveys provide key outcome measures, but qualitative data can enrich the understanding of barriers, motivators, and participants' perceptions. Adding interviews or focus groups could offer deeper insights into program impacts.

8. Diversify Economic Empowerment Activities

• Tailor vocational training to include more high-demand, scalable skills, and expand mentorship duration to ensure participants gain practical, sustainable income-generating capabilities.

9. Engage Influencers More Effectively

• The study showed promising results from engaging community leaders. Future interventions could expand this engagement to include more extensive workshops for parents, husbands, and community gatekeepers to amplify support for girls' empowerment.

10. Consider Scalability

• Evaluate cost-effectiveness and scalability of the combined intervention, ensuring that successful elements can be adapted and expanded to other regions or country

**********

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Reviewer #1: Yes:  AMOS M'YISA MAKELELE

Reviewer #2: No

**********

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PLoS One. 2025 Aug 25;20(8):e0330420. doi: 10.1371/journal.pone.0330420.r002

Author response to Decision Letter 1


29 Jan 2025

Editorial Review

When submitting your revision, we need you to address these additional requirements.

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The revised manuscript has been formatted aligning with the PLOS ONE style guidance

2. Please include a complete copy of PLOS’ questionnaire on inclusivity in global research in your revised manuscript. Our policy for research in this area aims to improve transparency in the reporting of research performed outside of researchers’ own country or community. The policy applies to researchers who have travelled to a different country to conduct research, research with Indigenous populations or their lands, and research on cultural artefacts. The questionnaire can also be requested at the journal’s discretion for any other submissions, even if these conditions are not met.  

Please find more information on the policy and a link to download a blank copy of the questionnaire here: https://journals.plos.org/plosone/s/best-practices-in-research-reporting

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The completed inclusivity in global research questionnaire has been submitted as a supporting information file (S7 File)

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This section has been deleted from the revised manuscript

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The caption for Fig 1 has been included in the revised manuscript

5. We are unable to open your Supporting Information file [S5 Dataset.dta, S6 Dataset.dta]. Please kindly revise as necessary and re-upload.

We thank the editorial team for catching this oversight. We have resubmitted the data files as CSV files (S5 File and S6 File) which should be able to open with the Microsoft suite

Additional Editor Comments:

Financial disclosure:

Please add “findings are discussion are the opinions of the authors and do not reflect the position of the sponsors”.

This has been updated in the submission platform as recommended

Introduction:

This section is too long. Even though no word limit provided in author’s guide, there is need to be concise and direct to the points relating to the objectives of the paper. The section now spans to about 5 pages and will be better if the section is concisely reduced to 2.5 pages. This will enable readers not to be lost regarding the study objectives.

Thank you for this suggestion. We have reduced the introduction section to fit into two and half pages.

The section will also benefit from basic statistics about reproductive health indicators among young girls globally and in Nigeria as well as statistics about poverty in this population (when compared to young men counterparts). The section should read like a scientific paper with facts (data) and not like a book.

We have enriched the introduction with more statistics citing the most recent Multiple Integrated Cluster Surveys of 2021 and the Nigeria Demographic Health Survey 2023/2024 on page 3.

Methods:

Recruitment: It is confusing how 400 participants relate to Table 1, whereby 12 groups and 24 upskills were reported. Please make this clearer or reconcile.

We thank the reviewer for the need to clarify this point. The SRH sessions for both the comparison (SRH only) group and the intervention (SRH and Economic Empowerment) group in both states consisted of a group of 12 adolescent girls. The economic empowerment sessions were nearly twice large in Ogun (sessions of 20 participants each) or equal to two times as large in Kaduna (sessions of 24 participants each). This clarification has been provided in Table 1 on page 8.

Sample size: it is unclear how the sample size of 400 was reached. Please elaborate.

We thank the editor for raising this important point. We estimated the sample size to detect a 10% difference in difference in the primary outcome variable (currently earning money) between the intervention and comparison groups and between the two study time points at the 95% confidence level assuming 50% in both groups were earning money at baseline with 80% power and a 10% attrition rate. This statement has been added in the sub-section on participant recruitment and sampling on page 10.

Measures: it will be good to clearly list and define all variables that were collected. Please group these variables into baseline and endline to enable proper comprehension.

We regret the lack of clarity on the study measures. Both baseline and endline included the same measures. Broadly, the measures were categorized into two domains (a) economic and (b) sexual and reproductive health. There were three measures for the economic domain, and all were binary variables - earning money, purchasing an asset using one's own money and contributing to household expenses. There were two measures for the SRH domain - current use of contraception and intention to use contraception in the future which were also binary variables. We have made revisions on page 11 and 12 to respond to this feedback.

Data confidentiality and security: this subsection is missing. Please provide the subsection.

We have included statements on this on page 13 starting on line 242.

Results:

Failure to clearly define variables of interests in the methods makes it difficult to follow and understand the results. There is abundant data and information that should be strategically presented. Consider reducing the length of the results section by referring the readers to appropriate tables for details. Lengthy results make it difficult to follow and link it to discussion and conclusion sections. Also consider using appropriate visuals to show comparison of key findings to enable comparison. This may also reduce the length of the results.

We regret the confusion the lack of clarity on the study measures affected the ease of following the results. We have addressed this concern in two ways. First, we have specified the measures in the methods section. Second, we have reduced the amount of text in the results section, allowing the reader to engage with the bulk of the results in the tables. We have added Fig 2 and Fig 3 to depict the changes that occurred for the measures in the two domains between baseline and endline. We have added the captions to these figures on page 18

Discussion and conclusion:

Please split the section into “Discussion” and “Conclusion and Recommendation”.

We appreciate this thoughtful suggestion. We have adopted this recommendation in the revised manuscript.

Will be good to be concise and to ensure discussion is within the scope and findings of this study.

This recommendation has been adopted.

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Is the manuscript technically sound, and do the data support the conclusions?

The manuscript must describe a technically sound piece of scientific research with data that supports the conclusions. Experiments must have been conducted rigorously, with appropriate controls, replication, and sample sizes. The conclusions must be drawn appropriately based on the data presented.

Reviewer #1: Yes

Reviewer #2: Partly

Shape

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

Shape

3. Have the authors made all data underlying the findings in their manuscript fully available?

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Reviewer #1: Yes

Reviewer #2: Yes

Shape

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Reviewer #1: Yes

Reviewer #2: Yes

Shape

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: The study addresses an important gap by examining the effects of integrated economic empowerment and sexual and reproductive health (SRH) interventions on adolescent girls in Nigeria. This is particularly valuable given the unique challenges faced by this demographic.

However there are some improvements I would recommend:

Abstract Clarity: The abstract is dense, especially in terms of results. It would be beneficial to streamline the findings to highlight the most impactful outcomes.

We have revised the abstract on page 2 by removing most of the numbers and rewording the results to reduce redundancy.

Introduction - Background Context: The background is comprehensive but could benefit from a more focused framing of the economic and SRH challenges specifically faced by adolescent girls in Nigeria. Additionally, contextualizing this intervention in the broader scope of Sub-Saharan Africa would help readers unfamiliar with the region.

We appreciate this feedback. We have been able to contextualize the background information to the context where the study was conducted and to the sub-Saharan Africa Context on page 3.

Methodological Details:

• Sampling and Recruitment: More details about the sampling process, including any potential biases, would enhance the transparency and replicability of the study

We are grateful for this thoughtful suggestion. We have reorganized the participant recruitment sub-section on page 9 and 10 to improve the flow and provided statements to clarify the sampling procedures. Selection bias could have occurred with the intervention group, because mobilisers might have preferred to select girls who were relatives, daughters of their friends or from the same religious group, ethnicity or clan with a motivation to ensure that the intervention reached those closer to them. We conducted a differential analysis comparing baseline characteristics between participants in the intervention and comparison group and found some differences (Table 2). To mitigate the influence of these differences in the analysis models, we included these variables as covariates in the difference-in-difference models. We have included a statement about selection bias under the study limitations on page 27.

• Covariates and Confounding: The manuscript mentions adjustments for certain covariates. It would be helpful to clarify why specific variables (e.g., age, education) were chosen and to justify their relevance in the analysis.

Under the sub-section on statistical analysis, we have included a statement on page 14 explaining how the covariates were selected. Briefly, evidence such as that from the synthesis by Stavropoulou M., (2018) identified age, parity and marital status as crucial determinants of the success of economic empowerment programs involving adolescent girls. We also considered variables as covariates if there were baseline group differences for this variable between the intervention and comparison group and this has been cited in the statement we have added.

Discussion and Implications:

Interpretation of Findings: The discussion could benefit from more critical reflection on why certain outcomes varied significantly between Kaduna and Ogun, particularly regarding SRH outcomes. Exploring cultural, social, or structural factors could provide readers with a more nuanced understanding.

Under the discussion section, we have included statements to illustrate why for some outcomes, intervention effects were detected in Kaduna or Ogun and not in both states such as line 413-416. We believe that differences in the age groups of the participants and marital status might account for the observed differences. Furthermore, our intention was not to compare outcomes between these groups because they are uniquely different and how the interventions were implemented was also contextualized to their life circumstances.

Program Duration and Sustainability: The study was conducted over a nine-month period, which limits long-term outcome assessment. Discussing the sustainability of these outcomes beyond the study period would be valuable.

We acknowledge that the sustainability of the intervention effects is a challenge with our evaluation. This program was designed to be implemented in a short time to demonstrate the feasibility of implementation and to illustrate potential for showing positive outcomes in the short-term. The program could not be continued for a long term because the investment by the financial partners was not availed. We have cited our inability to show the legacy of these outcomes as a limitation of our study under study limitations on lines 485-489 page 27.

Typographical Errors: A thorough proofreading would help eliminate minor typographical errors and improve readability.

We regret this error. We have rigorously reviewed the draft to increase accuracy and reduced wordiness to increase readability.

Reviewer #2: 

Expand the Timeline

The study observed changes over nine months, which might not fully capture the long-term effects of the intervention. Extending the study period would provide more robust insights into sustained outcomes, particularly in economic empowerment and contraceptive use.

We acknowledge this feedback. The long-term sustainability of the outcomes observed for economic empowerment interventions is a predominant concern for players in this sector. As we have responded to the second reviewer, we have cited the study’s inability to demonstrate the durability of the detected intervention effects as a limitation of our study. Our study was limited to nine months because of lack of financial resources to continue the investment beyond that. We take this as a missed opportunity because it is probable that our intervention contributed to larger and sustained outcomes in the medium and long-term as documented in unpublished data from qualitative interviews conducted with participants, mentors and session facilitators and husbands which affirmed the observed findings through increased involvement income generating activities and transformation of the girl’s decision-making power, agency and self efficacy. This is an important consideration that warrants additional research.

Address Attrition Issues

• Attrition rates were high, especially in Ogun. Future studies could employ strategies such as incentivizing participation, increasing community engagement, or using mobile follow-ups to reduce loss to follow-up and ensure a more representative sample at endline.

We appreciate the suggestions about how we could have mitigated the high attrition rates in Ogun. We explored some of these interventi

Attachment

Submitted filename: Responses to Reviewers.docx

pone.0330420.s007.docx (49KB, docx)

Decision Letter 1

Ibrahim Jahun

1 Aug 2025

Integrated economic and sexual and reproductive health programming among married and unmarried adolescent girls in Nigeria: results from a quasi-experimental cohort study

PONE-D-24-34510R1

Dear Dr. Philps,

We’re pleased to inform you that your manuscript has been judged scientifically suitable for publication and will be formally accepted for publication once it meets all outstanding technical requirements. Please disregard comments from reviewer #3. 

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Additional Editor Comments (optional):

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

Reviewer #3: All comments have been addressed

Reviewer #4: All comments have been addressed

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2. Is the manuscript technically sound, and do the data support the conclusions??>

Reviewer #3: Partly

Reviewer #4: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously? -->?>

Reviewer #3: Yes

Reviewer #4: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available??>

The PLOS Data policy

Reviewer #3: Yes

Reviewer #4: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English??>

Reviewer #3: Yes

Reviewer #4: Yes

**********

Reviewer #3: • The figures and tables are informative—ensure consistent labeling and that all are referenced in the text.

• Double-check all acronyms (e.g., SRH, EE) are spelled out on first use in each section.

• Carefully proofread again for minor grammatical inconsistencies (some still present in the revised version).

Final Assessment

thoroughly to reviewer comments.

• Well-structured, methodologically sound, policy-relevant.

• Minor issues:

• Results remain text-heavy.

• Slight inconsistencies in data interpretation across sections (e.g., Ogun attrition vs effect size).

Recommendation:

• Suitable for publication after minor textual refinements and attention to figure/table integration.

Reviewer #4: The title of the paper needs to be fine-tuned. You may change it to 'Integrated Economic and Sexual & Reproductive Health Programming for Married and Unmarried Adolescent Girls in Nigeria: Findings from a Quasi-Experimental Cohort Study'

**********

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Reviewer #3: No

Reviewer #4: Yes:  Mukhtar Liman Ahmed

**********

Acceptance letter

Ibrahim Jahun

PONE-D-24-34510R1

PLOS ONE

Dear Dr. Phillips,

I'm pleased to inform you that your manuscript has been deemed suitable for publication in PLOS ONE. Congratulations! Your manuscript is now being handed over to our production team.

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on behalf of

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Academic Editor

PLOS ONE

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 File. Program exposure questions.

    (DOCX)

    pone.0330420.s001.docx (29.3KB, docx)
    S1 Table. GEE model.

    (XLSX)

    pone.0330420.s002.xlsx (18.2KB, xlsx)
    S2 Table. Comparison of unadjusted and adjusted DiD.

    (DOCX)

    pone.0330420.s003.docx (22.5KB, docx)
    S3 Table. Differential attrition analysis table.

    (DOCX)

    pone.0330420.s004.docx (28.4KB, docx)
    S2 File. Questionnaire on inclusivity in global research.

    (DOCX)

    pone.0330420.s005.docx (74.4KB, docx)
    Attachment

    Submitted filename: Responses to Reviewers.docx

    pone.0330420.s007.docx (49KB, docx)

    Data Availability Statement

    The data supporting the findings in this study are publicly available in Figshare under a CC BY 4.0 license under the title “A360 Economic Strengthening Pilot Evaluation Dat Sets” and DOI: https://doi.org/10.6084/m9.figshare.29390573.v1.


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