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. 1981;320:187–192. doi: 10.1113/jphysiol.1981.sp013943

Healing-over in rat crystalline lens.

G Bernardini, C Peracchia, R A Venosa
PMCID: PMC1244041  PMID: 7320935

Abstract

1. 42K efflux has been studied in normal and injured rat crystalline lenses to test their ability to heal over. Following injury, a sizeable, but transient, increase in fractional loss of 42K takes place. 2. The lens healing-over is Ca-dependent and cannot be accounted for by membrane resealing. This is excluded by the fact that Procion Yellow gains access to damaged fibres even 2 hr after injury (when the healing-over is completed). 3. The occlusion of the junctional channels is the basic mechanism of healing-over. This is supported by the observation that Procion Yellow does not diffuse from damaged to intact fibres and by the Ca dependency of the phenomenon.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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