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. Author manuscript; available in PMC: 2025 Sep 30.
Published in final edited form as: Cell Metab. 2025 Aug 28;37(10):2093–2095. doi: 10.1016/j.cmet.2025.08.007

NANOG Metabolically Reprograms Tumor-Initiating Stem-like Cells through Tumorigenic Changes in Oxidative Phosphorylation and Fatty Acid Metabolism

Chia-Lin Chen, Dinesh Babu Uthaya Kumar, Vasu Punj, Jun Xu, Linda Sher, Stanley M Tahara, Sonja Hess, Keigo Machida *
PMCID: PMC12477616  NIHMSID: NIHMS2109241  PMID: 40876450

The authors of this study have noticed errors in the β-ACTIN immunoblot in Figures 1D, 2G, and 3E; IP: TAK1, followed by TAK1 western blot, in Figure 2F; the NANOG western blot in Figure 3E; and cytochrome c in Figure 7F. A different H&E-stained image of HCC of NS5A transgenic mice was incorporated into Figure 1E during figure preparation; these errors are not a correct representation of the data. These errors do not alter the results or conclusions of this study. The authors apologize that these errors were not detected earlier.

Figures 1D and 1E.

Figures 1D and 1E.

NANOG Plays a Critical Role in Liver Oncogenesis (corrected)

Figure 2.

Figure 2.

The Tumor Incidence in Several HCC Mouse Models Is TLR4-Dependent (corrected)

Figure 3E.

Figure 3E.

TLR4 Signaling Transactivates Nanog Promoter through E2F1 Binding Sites (corrected)

Figure 7F.

Figure 7F.

NANOG Orchestrated TIC Oncogenic and Therapeutic Resistance Mechanisms via Mitochondrial Metabolic Reprogramming (corrected)

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