NEUROBIOLOGY. For the article “Coupling asymmetry of heterotypic connexin 45/connexin 43-EGFP gap junctions: Properties of fast and slow gating mechanisms,” by Feliksas F. Bukauskas, A. Bukauskiene Angele, Vytas K. Verselis, and Michael V. L. Bennett, which appeared in number 10, May 14, 2002, of Proc. Natl. Acad. Sci. USA (99, 7113–7118), Fig. 2 appeared incorrectly. The correct figure and its legend appear below. In addition, the author name A. Bukauskiene Angele should read Angele Bukauskiene. The author's name has been corrected in the online journal.
Figure 2.
Vj gating of single Cx45 channels. (A) A negative and then a positive step of 60 mV were applied. At the beginning of the negative step a single channel was open (solid line) that showed closure to a substate of ≈4 pS (dashed lines), as well as a burst of apparently partial closings that were not well resolved. The closures were fast compared with the sampling interval of 2 ms. (B) Successive ramps repeated at 1/s showed fast gating to the residual state (first two ramps, dashed lines) and slow gating to the fully closed state (second two ramps, arrows). The channel was typically open at the onset of the ramp, closed at short latency, and then reopened (solid lines) at Vj approaching near zero.