Abstract
General and vascular surgeons are consulted occasionally to evaluate young adults with ischemia of the lower extremity. Between 1975 and 1985, 51 adults under 40 years of age who had arterial occlusive disease of the lower limb were managed. Although premature atherosclerosis was the most common problem (50%), claudication or limb-threatening ischemia also resulted from other sources (thromboembolism, popliteal artery entrapment, Buerger's disease, collagen vascular disease, and Takayasu's arteritis). Identifying the exact cause was sometimes difficult. The authors were impressed with the number of young adults who had delay in diagnosis and treatment (30 patients, 59%) before referral for a surgical opinion. In this paper, the attempt has been made to uncover the reasons for delayed diagnosis and to suggest a systematic approach that should lead to early recognition of lower extremity ischemia in this age group.
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- DEBAKEY M. E., CRAWFORD E. S., GARRETT H. E., COOLEY D. A., MORRIS G. C., Jr, ABBOTT J. P. OCCLUSIVE DISEASE OF THE LOWER EXTREMITIES IN PATIENTS 16 TO 37 YEARS OF AGE. Ann Surg. 1964 Jun;159:873–890. doi: 10.1097/00000658-196406000-00005. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Darling R. C., Buckley C. J., Abbott W. M., Raines J. K. Intermittent claudication in young athletes: Popliteal artery entrapment syndrome. J Trauma. 1974 Jul;14(7):543–552. doi: 10.1097/00005373-197407000-00001. [DOI] [PubMed] [Google Scholar]
- Karl R., Garlick I., Zarins C., Cheng E., Chediak J. Surgical implications of antithrombin III deficiency. Surgery. 1981 Apr;89(4):429–433. [PubMed] [Google Scholar]
- McCready R. A., Vincent A. E., Schwartz R. W., Hyde G. L., Mattingly S. S., Griffen W. O., Jr Atherosclerosis in the young: a virulent disease. Surgery. 1984 Nov;96(5):863–869. [PubMed] [Google Scholar]
- Müller N., Morris D. C., Nichols D. M. Popliteal artery entrapment demonstrated by CT. Radiology. 1984 Apr;151(1):157–158. doi: 10.1148/radiology.151.1.6701307. [DOI] [PubMed] [Google Scholar]
- Nunn D. B. Symptomatic peripheral arteriosclerosis of patients under age 40. Am Surg. 1973 Apr;39(4):224–228. [PubMed] [Google Scholar]
- O'Donnell T. F., Jr, Carvalho A. C., Colman R. W., Clowes G. H., Jr Platelet function abnormalities in a family with recurrent arterial thrombosis. Surgery. 1978 Feb;83(2):144–150. [PubMed] [Google Scholar]
- Pairolero P. C., Joyce J. W., Skinner C. R., Hollier L. H., Cherry K. J., Jr Lower limb ischemia in young adults: prognostic implications. J Vasc Surg. 1984 May;1(3):459–464. [PubMed] [Google Scholar]
- Rich N. M. Popliteal entrapment and adventitial cystic disease. Surg Clin North Am. 1982 Jun;62(3):449–465. doi: 10.1016/s0039-6109(16)42737-4. [DOI] [PubMed] [Google Scholar]
- Towne J. B., Bandyk D. F., Hussey C. V., Tollack V. T. Abnormal plasminogen: a genetically determined cause of hypercoagulability. J Vasc Surg. 1984 Nov;1(6):896–902. [PubMed] [Google Scholar]
- Towne J. B., Bernhard V. M., Hussey C., Garancis J. C. Antithrombin deficiency--a cause of unexplained thrombosis in vascular surgery. Surgery. 1981 Jun;89(6):735–742. [PubMed] [Google Scholar]
- Van Vroonhoven T. J. Intermittent claudication in premenopausal women. A correlation with the long-term use of oral contraceptives? J Cardiovasc Surg (Torino) 1977 May-Jun;18(3):291–295. [PubMed] [Google Scholar]

