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. 1987 Jul;51(3):363–366.

Immune response in skunks to a vaccinia virus recombinant expressing the rabies virus glycoprotein.

N D Tolson 1, K M Charlton 1, R B Stewart 1, J B Campbell 1, T J Wiktor 1
PMCID: PMC1255338  PMID: 3651890

Abstract

Striped skunks (Mephitis mephitis) were vaccinated with a vaccinia virus recombinant expressing the rabies virus glycoprotein. Virus neutralizing antibodies to rabies virus were present at 14 days postvaccination by the following routes: scarification (6/6), intramuscular (4/4) and intestinal (5/8). Six out of seven skunks that ate vaccine filled baits had virus neutralizing antibodies at 28 days. When challenged intramuscularly with street virus, the survival rates were 5/7 for the bait-fed group, 4/8 for the intestinal group, 3/4 for the intramuscular group, 5/6 for the animals that were scarified, and 0/8 for controls. This is the first report of a high rate of immunization of skunks with a rabies vaccine administered orally.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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