Abstract
Enteric infection with an attaching and effacing Escherichia coli was diagnosed in a puppy with protracted diarrhea. Extensive colonization of the small intestinal mucosa was observed by light and scanning electron microscopy and characteristic lesions of bacterial attachment of the brush border of the enterocytes were demonstrated by transmission electron microscopy. The E. coli strain isolated from the small intestine belonged to serotype O49:H10, did not produce any known E. coli enterotoxin or cytotoxin, was not invasive, and was negative for the known fimbrial colonization factors produced by animal and human enterotoxigenic E. coli. A positive immunoperoxidase reaction was obtained on the bacteria attached to the enterocytes with an anti-E. coli O49 antiserum.
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- Broes A., Fairbrother J. M., Larivière S., Jacques M., Johnson W. M. Virulence properties of enterotoxigenic Escherichia coli O8: KX105 strains isolated from diarrheic piglets. Infect Immun. 1988 Jan;56(1):241–246. doi: 10.1128/iai.56.1.241-246.1988. [DOI] [PMC free article] [PubMed] [Google Scholar]
- FOX I. W., HOAG W. G., STROUT J. BREED SUSCEPTIBILITY, PATHOGENICITY AND EPIDEMIOLOGY OF ENDEMIC COLIFORM ENTERITIS IN THE DOG. Lab Anim Care. 1965 Jun;15:194–200. [PubMed] [Google Scholar]
- Fairbrother J. M., Larivière S., Lallier R. New fimbrial antigen F165 from Escherichia coli serogroup O115 strains isolated from piglets with diarrhea. Infect Immun. 1986 Jan;51(1):10–15. doi: 10.1128/iai.51.1.10-15.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Levine M. M. Escherichia coli that cause diarrhea: enterotoxigenic, enteropathogenic, enteroinvasive, enterohemorrhagic, and enteroadherent. J Infect Dis. 1987 Mar;155(3):377–389. doi: 10.1093/infdis/155.3.377. [DOI] [PubMed] [Google Scholar]
- Moon H. W., Whipp S. C., Argenzio R. A., Levine M. M., Giannella R. A. Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines. Infect Immun. 1983 Sep;41(3):1340–1351. doi: 10.1128/iai.41.3.1340-1351.1983. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Moxley R. A., Francis D. H. Natural and experimental infection with an attaching and effacing strain of Escherichia coli in calves. Infect Immun. 1986 Aug;53(2):339–346. doi: 10.1128/iai.53.2.339-346.1986. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Peeters J. E., Charlier G. J., Halen P. H. Pathogenicity of attaching effacing enteropathogenic Escherichia coli isolated from diarrheic suckling and weanling rabbits for newborn rabbits. Infect Immun. 1984 Dec;46(3):690–696. doi: 10.1128/iai.46.3.690-696.1984. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Pospischil A., Mainil J. G., Baljer G., Moon H. W. Attaching and effacing bacteria in the intestines of calves and cats with diarrhea. Vet Pathol. 1987 Jul;24(4):330–334. doi: 10.1177/030098588702400407. [DOI] [PubMed] [Google Scholar]
- Rothbaum R. J., Partin J. C., Saalfield K., McAdams A. J. An ultrastructural study of enteropathogenic Escherichia coli infection in human infants. Ultrastruct Pathol. 1983 Jun;4(4):291–304. doi: 10.3109/01913128309140582. [DOI] [PubMed] [Google Scholar]
- SERENY B. Experimental keratoconjunctivitis shigellosa. Acta Microbiol Acad Sci Hung. 1957;4(4):367–376. [PubMed] [Google Scholar]