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. 1992 Oct;181(Pt 2):259–264.

Growth of the ribs at the costochondral junction in the rat.

T Peltomäki 1, L Häkkinen 1
PMCID: PMC1259721  PMID: 1295864

Abstract

The in situ growth of the ribs at the costochondral junction was examined by 2 methods. In the first, 3 threads were tied around the 5th, 6th or 7th ribs of 20-d-old rats. The first thread was located around the bony part of the rib close to the costochondral junction, the second around the cartilaginous part the same distance away from the junction, and the third also around the cartilaginous part but further away. The distances between the threads were measured at 20 and 40 d and were found to have increased considerably. In the second part, an immunohistochemical method using bromodeoxyuridine was employed to detect proliferating cells at the costochondral junction. The most active cell proliferation was observed in the proliferative zone, but mitoses were also noticed in the germinative zone. The results provide further evidence that the growth potential of costochondral grafts used in reconstructive surgery is related to the length of their cartilaginous portion.

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260Fig. 1
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262Fig. 2 (cont.)
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263Fig. 2
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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Agadir M., Sevastik B., Reinholt F. P., Perbeck L., Sevastik J. Vascular changes in the chest wall after unilateral resection of the intercostal nerves in the growing rabbit. J Orthop Res. 1990 Mar;8(2):283–290. doi: 10.1002/jor.1100080218. [DOI] [PubMed] [Google Scholar]
  2. Agadir M., Sevastik B., Sevastik J. A., Svensson L. Effects of intercostal nerve resection on the longitudinal rib growth in the growing rabbit. J Orthop Res. 1989;7(5):690–695. doi: 10.1002/jor.1100070509. [DOI] [PubMed] [Google Scholar]
  3. Apte S. S. Validation of bromodeoxyuridine immunohistochemistry for localization of S-phase cells in decalcified tissues. A comparative study with tritiated thymidine autoradiography. Histochem J. 1990 Aug;22(8):401–408. doi: 10.1007/BF01003459. [DOI] [PubMed] [Google Scholar]
  4. Copray J. C., Jansen H. W., Duterloo H. S. Growth and growth pressure of mandibular condylar and some primary cartilages of the rat in vitro. Am J Orthod Dentofacial Orthop. 1986 Jul;90(1):19–28. doi: 10.1016/0889-5406(86)90023-5. [DOI] [PubMed] [Google Scholar]
  5. Daniels S., Ellis E., 3rd, Carlson D. S. Histologic analysis of costochondral and sternoclavicular grafts in the TMJ of the juvenile monkey. J Oral Maxillofac Surg. 1987 Aug;45(8):675–683. doi: 10.1016/0278-2391(87)90306-5. [DOI] [PubMed] [Google Scholar]
  6. HARRIS W. R., MARTIN R., TILE M. TRANSPLANTATION OF EPIPHYSEAL PLATES. AN EXPERIMENTAL STUDY. J Bone Joint Surg Am. 1965 Jul;47:897–914. [PubMed] [Google Scholar]
  7. Heffez L., Doku H. C. The Goldenhar syndrome: diagnosis and early surgical management. Oral Surg Oral Med Oral Pathol. 1984 Jul;58(1):2–9. doi: 10.1016/0030-4220(84)90355-4. [DOI] [PubMed] [Google Scholar]
  8. Hunziker E. B., Schenk R. K., Cruz-Orive L. M. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. J Bone Joint Surg Am. 1987 Feb;69(2):162–173. [PubMed] [Google Scholar]
  9. Ippolito E., Mickelson M. R., Ponseti I. V. A histochemical study of slipped capital femoral epiphysis. J Bone Joint Surg Am. 1981 Sep;63(7):1109–1113. [PubMed] [Google Scholar]
  10. Kember N. F. Cell kinetics and the control of growth in long bones. Cell Tissue Kinet. 1978 Sep;11(5):477–485. doi: 10.1111/j.1365-2184.1978.tb00820.x. [DOI] [PubMed] [Google Scholar]
  11. Kuijpers-Jagtman A. M., Maltha J. C., Bex J. H., Daggers J. G. The influence of vascular and periosteal interferences on the histological structure of the growth plates of long bones. Anat Anz. 1987;164(4):245–254. [PubMed] [Google Scholar]
  12. Moss-Salentijn L., Moss M. L., Shinozuka M., Skalak R. Morphological analysis and computer-aided, three dimensional reconstruction of chondrocytic columns in rabbit growth plates. J Anat. 1987 Apr;151:157–167. [PMC free article] [PubMed] [Google Scholar]
  13. Peltomäki T. Growth of a costochondral graft in the rat temporomandibular joint. J Oral Maxillofac Surg. 1992 Aug;50(8):851–858. doi: 10.1016/0278-2391(92)90278-8. [DOI] [PubMed] [Google Scholar]
  14. Peltomäki T., Isotupa K. The costochondral graft: a solution or a source of facial asymmetry in growing children. A case report. Proc Finn Dent Soc. 1991;87(1):167–176. [PubMed] [Google Scholar]
  15. Peltomäki T., Rönning O. Interrelationship between size and tissue-separating potential of costochondral transplants. Eur J Orthod. 1991 Dec;13(6):459–465. doi: 10.1093/ejo/13.6.459. [DOI] [PubMed] [Google Scholar]
  16. Politis C., Fossion E., Bossuyt M. The use of costochondral grafts in arthroplasty of the temporomandibular joint. J Craniomaxillofac Surg. 1987 Dec;15(6):345–354. doi: 10.1016/s1010-5182(87)80081-1. [DOI] [PubMed] [Google Scholar]
  17. Poswillo D. E. Biological reconstruction of the mandibular condyle. Br J Oral Maxillofac Surg. 1987 Apr;25(2):100–104. doi: 10.1016/0266-4356(87)90003-9. [DOI] [PubMed] [Google Scholar]
  18. Poswillo D. Experimental reconstruction of the mandibular joint. Int J Oral Surg. 1974;3(6):400–411. doi: 10.1016/s0300-9785(74)80005-0. [DOI] [PubMed] [Google Scholar]
  19. RING P. A. The effects of partial or complete excision of the epiphyseal cartilage of the rabbit. J Anat. 1955 Jan;89(1):79–91. [PMC free article] [PubMed] [Google Scholar]
  20. ROY E. W., SARNAT B. G. Growth in length of rabbit ribs at the costochondral junction. Surg Gynecol Obstet. 1956 Oct;103(4):481–486. [PubMed] [Google Scholar]
  21. Robertson W. W., Jr Newest knowledge of the growth plate. Clin Orthop Relat Res. 1990 Apr;(253):270–278. [PubMed] [Google Scholar]
  22. SCHATTEN W. E., BERGENSTAL D. M., KRAMER W. M., SWARM R. L., SIEGEL S. Biological survival and growth of cartilage grafts. Plast Reconstr Surg Transplant Bull. 1958 Jul;22(1):11–28. doi: 10.1097/00006534-195807000-00002. [DOI] [PubMed] [Google Scholar]
  23. Seinsheimer F., 3rd, Sledge C. B. Parameters of longitudinal growth rate in rabbit epiphyseal growth plates. J Bone Joint Surg Am. 1981 Apr;63(4):627–630. [PubMed] [Google Scholar]
  24. Shimomura Y., Wezeman F. H., Ray R. D. The growth cartilage plate of the rat rib: cellular differentiation. Clin Orthop Relat Res. 1973 Jan-Feb;(90):246–254. [PubMed] [Google Scholar]
  25. Ware W. H., Brown S. L. Growth centre transplantation to replace mandibular condyles. J Maxillofac Surg. 1981 Feb;9(1):50–58. doi: 10.1016/s0301-0503(81)80012-4. [DOI] [PubMed] [Google Scholar]
  26. Ware W. H., Taylor R. C. Cartilaginous growth centers transplanted to replace mandibular condyles in monkeys. J Oral Surg. 1966 Jan;24(1):33–43. [PubMed] [Google Scholar]
  27. deFazio A., Leary J. A., Hedley D. W., Tattersall M. H. Immunohistochemical detection of proliferating cells in vivo. J Histochem Cytochem. 1987 May;35(5):571–577. doi: 10.1177/35.5.3549891. [DOI] [PubMed] [Google Scholar]

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