Abstract
Cortico-cortical connections of motor cortex in the marsupial brushtailed possum were traced by making injections of horseradish peroxidase (HRP) into two parts of motor cortex: the rostral agranular part which does not overlap somatosensory cortex, and the caudal part which does. Following injections in motor cortex, labelled neurons were observed on the same side of the brain within somatosensory areas 1 and 2 and in parietal cortex just caudal to S1, with most neurons in cortical Layers 2-4. Commissural connections were found in half of the experiments, with many labelled neurons in cortical Layer 5. We have compared the pattern of cortico-cortical connections in the possum with those seen in some other mammals, which appear generally similar.
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- Adams J. C. Stabilizing and rapid thionin staining of TMB-based HRP reaction product. Neurosci Lett. 1980 Apr;17(1-2):7–9. doi: 10.1016/0304-3940(80)90052-x. [DOI] [PubMed] [Google Scholar]
- Aitkin L. M., Gates G. R. Connections of the auditory cortex of the brush-tailed possum, Trichosurus vulpecula. Brain Behav Evol. 1983;22(2-3):75–88. doi: 10.1159/000121509. [DOI] [PubMed] [Google Scholar]
- Crewther D. P., Crewther S. G., Sanderson K. J. Primary visual cortex in the brushtailed possum: receptive field properties and corticocortical connections. Brain Behav Evol. 1984;24(4):184–197. doi: 10.1159/000121316. [DOI] [PubMed] [Google Scholar]
- Donoghue J. P., Parham C. Afferent connections of the lateral agranular field of the rat motor cortex. J Comp Neurol. 1983 Jul 10;217(4):390–404. doi: 10.1002/cne.902170404. [DOI] [PubMed] [Google Scholar]
- Donoghue J. P., Wise S. P. The motor cortex of the rat: cytoarchitecture and microstimulation mapping. J Comp Neurol. 1982 Nov 20;212(1):76–88. doi: 10.1002/cne.902120106. [DOI] [PubMed] [Google Scholar]
- Ebner F. F. Afferent connections to neocortex in the opossum (Didelphis virginiana). J Comp Neurol. 1967 Mar;129(3):241–268. doi: 10.1002/cne.901290303. [DOI] [PubMed] [Google Scholar]
- Foster R. E., Donoghue J. P., Ebner F. F. Laminar organization of efferent cells in the parietal cortex of the Virginia opossum. Exp Brain Res. 1981;43(3-4):330–336. doi: 10.1007/BF00238375. [DOI] [PubMed] [Google Scholar]
- Gates G. R., Aitkin L. M. Auditory cortex in the marsupial possum Trichosurus vulpecula. Hear Res. 1982 May;7(1):1–11. doi: 10.1016/0378-5955(82)90078-8. [DOI] [PubMed] [Google Scholar]
- Goldby F. An experimental investigation of the motor cortex and its connexions in the phalanger, Trichosurus vulpecula. J Anat. 1939 Oct;74(Pt 1):12–33. [PMC free article] [PubMed] [Google Scholar]
- Haight J. R., Neylon L. An analysis of some thalamic projections to parietofrontal neocortex in the marsupial native cat, Dasyurus viverrinus (Dasyuridae). Brain Behav Evol. 1981;19(3-4):193–204. doi: 10.1159/000121642. [DOI] [PubMed] [Google Scholar]
- Haight J. R., Neylon L. The organization of neocortical projections from the ventrolateral thalamic nucleus in the brush-tailed possum, Trichosurus vulpecula, and the problem of motor and somatic sensory convergence within the mammalian brain. J Anat. 1979 Dec;129(Pt 4):673–694. [PMC free article] [PubMed] [Google Scholar]
- Haight J. R., Neylon L. The organization of neocortical projections from the ventroposterior thalamic complex in the marsupial brush-tailed possum, Trichosurus vulpecula: a horseradish peroxidase study. J Anat. 1978 Aug;126(Pt 3):459–485. [PMC free article] [PubMed] [Google Scholar]
- Heath C. J., Jones E. G. Interhemispheric pathways in the absence of a corpus callosum. An experimental study of commissural connexions in the marsupial phalanger. J Anat. 1971 Jul;109(Pt 2):253–270. [PMC free article] [PubMed] [Google Scholar]
- Jenny A. B. Commissural projections of the cortical hand motor area in monkeys. J Comp Neurol. 1979 Nov 1;188(1):137–145. doi: 10.1002/cne.901880111. [DOI] [PubMed] [Google Scholar]
- Jones E. G., Coulter J. D., Hendry S. H. Intracortical connectivity of architectonic fields in the somatic sensory, motor and parietal cortex of monkeys. J Comp Neurol. 1978 Sep 15;181(2):291–347. doi: 10.1002/cne.901810206. [DOI] [PubMed] [Google Scholar]
- Jones E. G., Wise S. P. Size, laminar and columnar distribution of efferent cells in the sensory-motor cortex of monkeys. J Comp Neurol. 1977 Oct 15;175(4):391–438. doi: 10.1002/cne.901750403. [DOI] [PubMed] [Google Scholar]
- Jürgens U. The efferent and afferent connections of the supplementary motor area. Brain Res. 1984 May 21;300(1):63–81. doi: 10.1016/0006-8993(84)91341-6. [DOI] [PubMed] [Google Scholar]
- Kaas J. H., Nelson R. J., Sur M., Lin C. S., Merzenich M. M. Multiple representations of the body within the primary somatosensory cortex of primates. Science. 1979 May 4;204(4392):521–523. doi: 10.1126/science.107591. [DOI] [PubMed] [Google Scholar]
- LENDE R. A. MOTOR REPRESENTATION IN THE CEREBRAL CORTEX OF THE OPOSSUM (DIDELPHIS VIRGINIANA). J Comp Neurol. 1963 Dec;121:405–415. doi: 10.1002/cne.901210308. [DOI] [PubMed] [Google Scholar]
- LENDE R. A. SENSORY REPRESENTATION IN THE CEREBRAL CORTEX OF THE OPOSSUM (DIDELPHIS VIRGINIANA). J Comp Neurol. 1963 Dec;121:395–403. doi: 10.1002/cne.901210307. [DOI] [PubMed] [Google Scholar]
- Martin G. F., Bresnahan J. C., Henkel C. K., Megirian D. Corticobulbar fibres in the North American opossum (Didelphis marsupialis virginiana) with notes on the Tasmanian brust-tailed possum (Trichosurus vulpecula) and other marsupials. J Anat. 1975 Dec;120(Pt 3):439–484. [PMC free article] [PubMed] [Google Scholar]
- Martin G. F., Megirian D. Corticobulbar projections of the marsupial phalanger (Trichosurus vulpecula). II. Projections to the mesencephalon. J Comp Neurol. 1972 Feb;144(2):165–192. doi: 10.1002/cne.901440203. [DOI] [PubMed] [Google Scholar]
- Martin G. F., Megirian D., Roebuck A. Corticobulbar projections of the marsupial phalanger (Trichosurus vulpecula). I. Projections to the pons and medulla oblongata. J Comp Neurol. 1971 Jul;142(3):275–295. doi: 10.1002/cne.901420303. [DOI] [PubMed] [Google Scholar]
- Matelli M., Camarda R., Glickstein M., Rizzolatti G. Interconnections within the postarcuate cortex (area 6) of the macaque monkey. Brain Res. 1984 Sep 24;310(2):388–392. doi: 10.1016/0006-8993(84)90167-7. [DOI] [PubMed] [Google Scholar]
- Mesulam M. M. Tetramethyl benzidine for horseradish peroxidase neurohistochemistry: a non-carcinogenic blue reaction product with superior sensitivity for visualizing neural afferents and efferents. J Histochem Cytochem. 1978 Feb;26(2):106–117. doi: 10.1177/26.2.24068. [DOI] [PubMed] [Google Scholar]
- Miller M. W., Vogt B. A. Direct connections of rat visual cortex with sensory, motor, and association cortices. J Comp Neurol. 1984 Jun 20;226(2):184–202. doi: 10.1002/cne.902260204. [DOI] [PubMed] [Google Scholar]
- Neylon L., Haight J. R. Neocortical projections of the suprageniculate and posterior thalamic nuclei in the marsupial brush-tailed possum, Trichosurus vulpecula (Phalangeridae), with a comparative commentary on the organization of the posterior thalamus in marsupial and placental mammals. J Comp Neurol. 1983 Jul 10;217(4):357–375. doi: 10.1002/cne.902170402. [DOI] [PubMed] [Google Scholar]
- Porter L. L., White E. L. Afferent and efferent pathways of the vibrissal region of primary motor cortex in the mouse. J Comp Neurol. 1983 Mar 1;214(3):279–289. doi: 10.1002/cne.902140306. [DOI] [PubMed] [Google Scholar]
- Rees S., Hore J. The motor cortex of the brush-tailed possum (Trichosurus vulpecula): motor representation, motor function and the pyramidal tract. Brain Res. 1970 Jun 15;20(3):439–451. doi: 10.1016/0006-8993(70)90173-3. [DOI] [PubMed] [Google Scholar]
- Robinson C. J., Burton H. Organization of somatosensory receptive fields in cortical areas 7b, retroinsula, postauditory and granular insula of M. fascicularis. J Comp Neurol. 1980 Jul 1;192(1):69–92. doi: 10.1002/cne.901920105. [DOI] [PubMed] [Google Scholar]
- Sanderson K. J., Welker W., Shambes G. M. Reevaluation of motor cortex and of sensorimotor overlap in cerebral cortex of albino rats. Brain Res. 1984 Feb 6;292(2):251–260. doi: 10.1016/0006-8993(84)90761-3. [DOI] [PubMed] [Google Scholar]
- Strick P. L., Preston J. B. Two representations of the hand in area 4 of a primate. I. Motor output organization. J Neurophysiol. 1982 Jul;48(1):139–149. doi: 10.1152/jn.1982.48.1.139. [DOI] [PubMed] [Google Scholar]
- Welker C. Microelectrode delineation of fine grain somatotopic organization of (SmI) cerebral neocortex in albino rat. Brain Res. 1971 Mar 5;26(2):259–275. [PubMed] [Google Scholar]