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. 1988 Oct;160:145–155.

Response of intraventricular macrophages after a penetrant cerebral lesion.

W L Maxwell 1, J McGadey 1
PMCID: PMC1262057  PMID: 3253252

Abstract

The response of epiplexus and supraependymal cells to extravasated blood after a penetrant cerebral lesion was investigated. Epiplexus cells respond more actively than supraependymal cells. The epiplexus cells tend to aggregate near areas of extravasation of erythrocytes, this being most marked 6 hours after injury. Epiplexus cells lose their smooth surface appearance, retract their filopodia and adopt a more spherical form, with short microvilli or blebs. Numerous inclusion vesicles develop; some contain disrupted erythrocytes 6-12 hours after injury and these are still present 24-30 hours after injury. By 8-16 days after injury epiplexus cells resume a smooth surface appearance and the number of inclusion vesicles is much reduced. This suggests reversion to a quiescent state, from an earlier active state.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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