Abstract
Endometrial biopsies were taken for histological assessment from 97 cows which calved in a commercial dairy herd between April and August 1984. The main objectives of this study were to analyze the interrelationships among histological criteria and to identify a shortlist of histological parameters to be included in subsequent analysis of associations with results of bacteriological culture, clinical findings and reproductive performance. Epithelial height and segmented cell counts were highly correlated within biopsy, between horns and between days. Subjective assessment of inflammation in the epithelium and/or stratum compactum generally identified biopsies which had any inflammation present. Cows which had inflammation in a biopsy from day 26 were likely to show inflammatory changes at day 40. Quantitative and subjective assessments of gland number, dilation and fibrosis were highly correlated. There was a positive association between the number of cross sections and the diameter of glands, and both of these criteria were negatively correlated with fibrosis and inflammatory changes. There may be different functional significance of the same histological finding at a different number of days postpartum.
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- Bonnett B. N., Etherington W. G., Martin S. W., Johnson W. H. The effect of prostaglandin administration to Holstein-Friesian cows at Day 26 postpartum on clinical findings, and histological and bacteriological results of endometrial biopsies at Day 40. Theriogenology. 1990 Apr;33(4):877–890. doi: 10.1016/0093-691x(90)90823-c. [DOI] [PubMed] [Google Scholar]
- Bonnett B. N., Martin S. W., Gannon V. P., Miller R. B., Etherington W. G. Endometrial biopsy in Holstein-Friesian dairy cows. III. Bacteriological analysis and correlations with histological findings. Can J Vet Res. 1991 Apr;55(2):168–173. [PMC free article] [PubMed] [Google Scholar]
- Bonnett B. N., Miller R. B., Etherington W. G., Martin S. W., Johnson W. H. Endometrial biopsy in Holstein-Friesian dairy cows. I. Technique, histological criteria and results. Can J Vet Res. 1991 Apr;55(2):155–161. [PMC free article] [PubMed] [Google Scholar]
- Etherington W. G., Martin S. W., Bonnett B., Johnson W. H., Miller R. B., Savage N. C., Walton J. S., Montgomery M. E. Reproductive performance of dairy cows following treatment with cloprostenol 26 and/or 40 days postpartum: a field trial. Theriogenology. 1988;29(3):565–575. doi: 10.1016/s0093-691x(88)80005-0. [DOI] [PubMed] [Google Scholar]
- Gier H. T., Marion G. B. Uterus of the cow after parturition: involutional changes. Am J Vet Res. 1968 Jan;29(1):83–96. [PubMed] [Google Scholar]
- Studer E., Morrow D. A. Postpartum evaluation of bovine reproductive potential: comparison of findings from genital tract examination per rectum, uterine culture, and endometrial biopsy. J Am Vet Med Assoc. 1978 Feb 15;172(4):489–494. [PubMed] [Google Scholar]
- Thomas D. C., Siemiatycki J., Dewar R., Robins J., Goldberg M., Armstrong B. G. The problem of multiple inference in studies designed to generate hypotheses. Am J Epidemiol. 1985 Dec;122(6):1080–1095. doi: 10.1093/oxfordjournals.aje.a114189. [DOI] [PubMed] [Google Scholar]