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Frontiers in Immunology logoLink to Frontiers in Immunology
. 2025 Nov 7;16:1727580. doi: 10.3389/fimmu.2025.1727580

Correction: Emerging strategies in colorectal cancer immunotherapy: enhancing efficacy and survival

Yu Zhang 1, Haixia Guan 1, Xixuan Feng 1, Mengyan Liu 1, Jinhuan Shao 1, Mengchi Liu 1, Jialei He 1, Yahui Jin 1,*, Jinglin Zhu 1,*, Chunli Zheng 1,*
PMCID: PMC12634591  PMID: 41280928

There was a mistake in Table 7 as published. The phases corresponding to NCT06751966 and NCT06751914 were omitted. The corrected Table 7 appears below.

Table 7.

Clinical trials based on neoantigen vaccines for the treatment of colorectal cancer.

ClinicalTrials.Gov identifier Combinatorial agent(s) Phase Primary endpoint Status
NCT03948763 Pembrolizumab Phase 1 DLTs Terminated
NCT06195384 Phase 1 Safety Recruiting
NCT06496373 Phase 1 Reaction of antigen-specific T cells Recruiting
NCT05359354 Not Applicable MTD,DLTs Recruiting
NCT05916248 Pembrolizumab Phase 1 MTD,DLTs,ORR,DCR Recruiting
NCT05940181 Sintilimab Interventional MTD,DLTs,Safety Recruiting
NCT06497010 Phase 1 RP2D Recruiting
NCT03639714 Nivolumab;Ipilimumab Phase 1,2 TEAEs,DLTs,ORR, RP2D Completed
NCT06751966 Not Applicable ORR,DCR,Safety Recruiting
NCT06751914 Not Applicable ORR,DCR,Safety Recruiting
NCT04147078 Phase 1 DFS Recruiting
NCT04117087 Nivolumab;Ipilimumab Phase 1 Safety,Fold change in CD8 and CD4 T cells Recruiting
NCT02600949 Phase 1 Feasibility,TEAEs Recruiting
NCT03552718 Phase 1 Safety,RP2D Active
NCT04041310 Pembrolizumab Phase 1,2 DLTs,ORR,Safety,
Tolerability
Active
NCT03953235 Nivolumab;Ipilimumab Phase 1,2 TEAEs,DLTs,
ORR, RP2D
Completed
NCT04912765 Nivolumab Phase 2 PFS Recruiting
NCT06522919 Pembrolizumab Phase 2 ORR,PFS Recruiting
NCT05141721 Atezolizumab;Fluoropyrimidine;Bevacizumab;Ipilimumab Phase 2,3 ctDNA,PFS Active

The original version of this article has been updated.

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