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. 1965 Nov;97(2):569–572. doi: 10.1042/bj0970569

The disulphide bonds of human and rabbit γ-globulins

R Cecil 1, G T Stevenson 1,*
PMCID: PMC1264677  PMID: 16749166

Abstract

1. The reaction of the disulphide bonds of the predominant species of human and rabbit γ-globulins (the 7s γ-globulins) with sulphite was studied in the presence and absence of denaturing agents and heavy-metal reagents. 2. The total number of bonds reacting/mol. of mol.wt. 160000 was approx. 18 for human and 20 for rabbit γ-globulin. 3. Six S·S bonds/mol. of human and 6·5 S·S bonds/mol. of rabbit γ-globulin reacted with sulphite alone at pH6. These appeared to include all the interchain S·S bonds. 4. The number of free SH groups was less than 0·2/mol. of human and less than 0·3/mol. of rabbit γ-globulin.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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