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. 1965 Dec;97(3):766–768. doi: 10.1042/bj0970766

Isolation of a naphthaquinone with partly hydrogenated side chain from Corynebacterium diphtheriae

P B Scholes 1, H K King 1
PMCID: PMC1264757  PMID: 4956562

Abstract

1. Corynebacterium diphtheriae contains relatively large amounts (6·6μmoles/g. dry wt.) of a naphthaquinone whose ultraviolet-absorption spectrum is that of a typical menaquinone (vitamin K2), the E1%1 cm. value corresponding with that of MK-8, but on reversed-phase paper chromatograms it runs with MK-9. 2. In the presence of Adams catalyst hydrogen uptake is 2 atoms/mol. less than that calculated for MK-8. 3. Hydrogenated samples of the Corynebacterium quinone and the hydrogenation product of authentic MK-8 ran together on reversed-phase chromatograms. 4. Infrared-absorption spectra indicated close relationship with the menaquinone series, and nuclear-magnetic-resonance measurements show that one, non-terminal, double bond of the side chain has been saturated. 5. The compound is thus designated MK-8(2H), indicating a menaquinone with eight isoprene units but only seven double bonds in the side chain.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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