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. 1966 Jan;98(1):100–104. doi: 10.1042/bj0980100

The inhibition of phosphoglucomutase by beryllium

W N Aldridge 1, Molly Thomas 1
PMCID: PMC1264800  PMID: 5938629

Abstract

1. The inhibition of phosphoglucomutase by beryllium has been examined. 2. Inhibition by beryllium does not occur unless a complex-forming agent such as cysteine or imidazole is present. It is therefore similar to activation by magnesium. 3. The inhibition is progressive and the rate follows first-order kinetics, which may be defined by a bimolecular rate constant. 4. In the presence of magnesium the rate of inhibition is less. By using a fixed time for inhibition competition between beryllium and magnesium may be demonstrated. After inhibition has taken place, the addition of magnesium does not reverse it.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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