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Biochemical Journal logoLink to Biochemical Journal
. 1966 Mar;98(3):669–677. doi: 10.1042/bj0980669

The dietary-regulated biosynthesis of high-sulphur wool proteins

J M Gillespie 1,2, P J Reis 1,2
PMCID: PMC1264905  PMID: 5911515

Abstract

1. When the diet of sheep is supplemented by the abomasal infusion of sulphur-containing amino acids or casein, a special group of proteins, with a very high content of sulphur (about 8·3%), is incorporated into the high-sulphur proteins of wool. These special proteins cannot be detected in control wool from the same sheep. 2. This is a naturally occurring process, as these special proteins are found in wool from sheep on a high level of nutrition under ordinary conditions of feeding, and in wool of an inherently high sulphur content. 3. This represents a control mechanism in protein synthesis that has not previously been observed, and may be further evidence that the high-sulphur proteins of wool are produced by an unusual synthetic route.

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