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. 1966 Nov;101(2):328–337. doi: 10.1042/bj1010328

The phosphatidylinositol kinase of rat brain

M Kai 1, G L White 1, J N Hawthorne 1
PMCID: PMC1270113  PMID: 4290722

Abstract

1. The presence of a phosphatidylinositol kinase in homogenates of adult rat brain was shown by using labelled ATP or labelled phosphatidylinositol. 2. The kinase was activated by Mg2+ or Mn2+ and inhibited by Ca2+, Cu2+, K+, Na+ and F−. 3. The detergents sodium deoxycholate, Cutscum and Triton X-100 markedly stimulated the reaction; sodium taurocholate, Tween-20 and cetyltrimethyl-ammonium bromide were less effective. 4. The activity of the enzyme was dependent on SH groups. 5. The subcellular distribution of the kinase in brain resembled that of Na+-plus-K+-stimulated adenosine triphosphatase and 5′-nucleotidase.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

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